Results 31 to 40 of about 447,223 (260)

Treatment outcomes of acute streptococcal tonsillitis according to antibiotic treatment. A retrospective analysis of 242,366 cases treated in the community

European Journal of General Practice, 2022
Background Acute upper respiratory infections are the most common reason for primary physician visits in the community. This study investigated whether the type of antibiotic used to treat streptococcal tonsillitis can reduce the burden by affecting the ...
Mattan Bar-Yishay, Ilan Yehoshua, Avital Bilitzky, Yan Press   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Antibiotic Driven Changes in Gut Motility Suggest Direct Modulation of Enteric Nervous System

Frontiers in Neuroscience, 2017
Antibiotic-mediated changes to the intestinal microbiome have largely been assumed to be the basis of antibiotic-induced neurophysiological and behavioral changes.
Thilini Delungahawatta, Thilini Delungahawatta, Jessica Y. Amin, Andrew M. Stanisz, John Bienenstock, John Bienenstock, Paul Forsythe, Paul Forsythe, Paul Forsythe, Wolfgang A. Kunze, Wolfgang A. Kunze, Wolfgang A. Kunze   +11 more
doaj   +1 more source

Resistance of Vibrio cholera to antibiotics that inhibit cell wall synthesis: A systematic review and meta-analysis

Frontiers in Pharmacology, 2023
Objective: Cholera is a challenging ancient disease caused by Vibrio cholera (V. cholera). Antibiotics that prevent cell wall synthesis are among the first known antibiotic groups. Due to its high consumption, V.
Hossein Nateghizad, Rojina Sajadi, Ali Shivaee, Omid Shirazi, Mohadeseh Sharifian, Danyal Abbasi Tadi, Kumarss Amini   +6 more
doaj   +1 more source

Penicillin V [PDF]

BMJ, 1956
F D, HART, D, BURLEY, R, MANLEY, G, BROWN   +3 more
  +5 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

PRODUKSI PENISILIN OLEH Penicillium chrysogenum L112 DENGAN VARIASI KECEPATAN AGITASI PADA FERMENTOR 1 L

Kartika: Jurnal Ilmiah Farmasi, 2016
ABSTRAKPenisilin merupakan golongan antibiotika β-laktam yang memiliki nilai komersial tinggi karenadigunakan secara luas untuk memproduksi antibiotik semisintetik lain (amoksilin, ampisilin) sertamempunyai kemampuan mengatasi infeksi yang disebabkan ...
Saadah D Rachman, Agus Safari, Fazli Fazl, Dian S Kamara, Abubakar Sidik, Linar Z Udin, Safri Ishmayana   +6 more
doaj   +1 more source

Impact of narrow-spectrum penicillin V on the oral and faecal resistome in a young child treated for otitis media

Journal of Global Antimicrobial Resistance, 2020
Objectives: Antibiotic overuse has led to the global emergence of antimicrobial-resistant bacteria, and children are among the most frequent users of antibiotics.
Kjersti Sturød, Achal Dhariwal, Ulf R. Dahle, Didrik F. Vestrheim, Fernanda C. Petersen   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source