Results 151 to 160 of about 170,743 (345)

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Molecular Imprinted Polymers for Penicillins and Tetracyclines

Антибиотики и Химиотерапия, 2020
The molecular imprinted polymers (MIPs) for penicillins and tetracyclines described in the literature were analysed with a purpose of evaluating their possible use for the antibiotic sorption isolation.
M. I. Yakhkind, K. R. Tarantseva, M. A. Marynova, P. A. Storozhenko, M. M. Rasulov   +4 more
doaj  

Hydrolysis of 6-alkyl penicillins catalysed by ?-lactamase I from Bacillus cereus and by hydroxide ion

, 1988
Second-order rate constants for the hydroxide ion-catalysed hydrolysis of 6-alkyl penicillins are independent of the length of the alkyl side-chain and replacement of the amido by an amino group decreases the susceptibility to nuclephilic attack on 6 ...
Page, Michael I., Longridge, Jethro L., Buckwell, Stephen C.   +2 more
core   +1 more source

Streptococcus faecium mutants that are temperature sensitive for cell growth and show alterations in penicillin-binding proteins

, 1987
Pietro Canepari, Maria M. Lleò, Roberta Fontana, G Satta   +3 more
openalex   +2 more sources

Molecular Analysis of the Genetic Variation among Penicillin‐Susceptible and Penicillin‐ResistantStreptococcus pneumoniaeSerotypes in Canada [PDF]

, 1999
Marie Louie, Lisa Louie, Giuseppe Papia, James Talbot, Marguerite Lovgren, A. E. Simor   +5 more
openalex   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Improvements in the Cylinder-Plate Method for Penicillin Assay [PDF]

, 1945
G. W. Beadle, Herschel K. Mitchell, David M. Bonner   +2 more
openalex   +1 more source

Incorporation of Selenium into Sol–Gel‐Derived Bioactive Glass: Influence on Glass Structure, Bioactivity, and its Selective Cytotoxicity

Advanced Engineering Materials, EarlyView.
Selenium was incorporated into a sol–gel‐derived bioactive glass to enable sustained therapeutic ion release. The selenium‐containing glass preserved bioactivity while selectively inducing cytotoxicity in osteosarcoma cells and maintaining osteoblastic viability.
Breno Rocha Barrioni, Thalita Marcolan Valverde, Talita Martins, Guilherme Mattos Jardim Costa, Alfredo Miranda de Goes, Marcello Rosa Dumont, Eduardo Henrique Martins Nunes, Marivalda de Magalhães Pereira   +7 more
wiley   +1 more source

Penicillin Hypersensitivity: Detection by Basophil Response to Challenge**From the Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.

, 1965
Sorrel S. Resnik, Walter B. Shelley
openalex   +1 more source

Direct Metal Deposition of Graphene–Ti28Nb35.4Zr Matrix Composites With Enhanced Mechanical, Corrosion, and Biocompatibility Properties for Bone Implants

Advanced Engineering Materials, EarlyView.
Graphene nanoplatelet (0.1 wt.%) reinforcement significantly enhances the performance of β Ti‐28Nb‐35.4Zr alloy. Grain refinement, reduced water contact angle, and improved surface characteristics promote osteoblast adhesion and complete surface coverage after 7 days.
Khurram Munir, Jixing Lin, Yuncang Li, Li Zhu, Paul F. A. Wright, Cuie Wen   +5 more
wiley   +1 more source