Results 141 to 150 of about 170,743 (345)

Rapid Capillary Tube Method for Detecting Penicillin Resistance in Staphylococcus aureus [PDF]

, 1972
Ira G. Rosen, Julie Jacobson, Randal Rudderman   +2 more
openalex   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

SIDE-CHAIN SPECIFICITY IN THE ENZYMATIC-SYNTHESIS OF PENICILLINS

, 1990
5-Carboxynaphth-1-oyl-, 4-carboxybenxoyl-,trans-5-carboxy-3-pentenoyl- and cis-5-carboxy-3-pentenoyl-L-cysteinyl-D-valine were shown to be converted by isopenicillin N synthetase to their corresponding penicillins in yields of 90%, 12%, 40% and 5 ...
SCHOFIELD, C, Bradley D. Smith, Jack E. Baldwin, Christopher J. Schofield, BALDWIN, J, SMITH, B   +5 more
core   +1 more source

Penicillin-resistant Variants of Pneumococci [PDF]

, 1968
J. B. Gunnison, Margaret A. Fraher, Elisabeth A. Pelcher, Ernest Jawetz   +3 more
openalex   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

A systematic review and meta-analysis of randomized controlled trials of systemic antibiotics for diabetes-related foot infections

Diabetes & Vascular Disease Research
Objective Diabetes-related foot infections (DFIs) are prevalent in patients with diabetes mellitus, often leading to severe complications, including amputations.
Mei-Chuan Lee, Yi-Ming Hua, Han Siong Toh, Hui-Chen Su, Po-Jung Chen   +4 more
doaj   +1 more source

Proportional use within penicillins in hospital care among seven regions in 2014.

, 2018
Proportional use within penicillins in hospital care among seven regions in 2014.
Aitian Yin (289788), Panpan Dong (1492564), Shusheng Huang (5171663), Xiaoyuan Qu (5171666), Xihong Sun (5171660), Xiufang Lu (5171672), Chang Yin (5171669), Chaofan Li (176970), Zhuo Zhang (72795)   +8 more
core   +1 more source

PENICILLIN [PDF]

British Journal of Ophthalmology, 1945
openaire   +2 more sources

Systematic Review and Meta-analysis of the Safety of Antistaphylococcal Penicillins Compared to Cefazolin

Antimicrobial Agents and Chemotherapy, 2018
K. Eljaaly, Samah Alshehri, B. Erstad
semanticscholar   +1 more source