Results 121 to 130 of about 36,910 (309)

Theoretical study of thiolysis in penicillins and cephalosporins [PDF]

[eng] Semiempirical calculations were used to conduct a comprehensive study of the thiolysis of the fundamental core of penicillins and cephalosporins.
Garcías Llabrés, Rafael, Donoso Pardo, Josefa Laurentina, Vilanova Canet, Bartolomé, Coll, Miguel, Muñoz Izquierdo, Francisco   +4 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Induction and characterization of multianalyte antibodies against penicillins in egg yolk [PDF]

, 1997
Antibodies against penicillins were induced in eggs of laying hens after immunization with 6-aminopenicillanic acid (6-APA) coupled to keyhole limpet hemocyanin (KLH).
Petz, M., Kan, C.A., de Leuw, P., Kapa, G., Schreurs, F.J.G.   +4 more
core   +2 more sources

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Penicillin Allergy, Really?—A Cross-Sectional Mixed-Methods Study in Baden-Württemberg, Germany, to Explore General Practitioner Perspectives on Delabeling Potential in Primary Care

Antibiotics
Background: Most penicillin allergy labels are documented in early childhood and result from events of low risk for allergy. In Germany, evidence-based strategies to evaluate the likelihood of a true penicillin allergy are still lacking.
Regina Poß-Doering, Nicola A. Litke, Elham Khatamzas, Attila Altiner   +3 more
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

The Estimation of Penicillins and Penicillin Destruction [PDF]

Journal of Pharmacy and Pharmacology, 1963
J M, HAMILTON-MILLER, J T, SMITH, R, KNOX   +2 more
openaire   +2 more sources

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Molecular modelling of four penicillins: bencylpenicillin, phenoxymethylpenicillin, ampicillin and amoxicillin [PDF]

, 2009
Background:Penicillins differ structurally among themselves by the lateral chains. At the same time, they have differences in their pharmacological action that can be associated to modifications included in the betalactamic ring and/or effects localized ...
Eslhey María Sánchez Domínguez, Elso Manuel Cruz Cruz   +1 more
core   +1 more source

Antibiotic Prescribing for Cellulitis in the Absence of Penicillin‐Cephalosporin Cross‐Reactivity Alerts: A Retrospective Study

Pharmacology Research & Perspectives
Cephalosporins are often avoided in patients with penicillin adverse drug reaction (ADR) labels. In our institution's electronic medication management system, penicillin and cephalosporin ADR labels do not generate cross‐reactivity alerts.
Milan Sundermann, James A. H. Mehrtens, Nicholas M. Douglas, Sharon J. Gardiner, Matthew Doogue, Paul K. L. Chin   +5 more
doaj   +1 more source