Results 121 to 130 of about 170,743 (345)

The chemical reactivity of penicillins and other b-lactam antibiotics

The rates of the acid catalysed hydrolysis of penicillins and cephalosporins are linear in Ho and, unlike other amides, show no rate maximum with increasing acidity.
Page, Michael I., Gensmantel, Nigel P., Proctor, Philip   +2 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Penicillin Allergy, Really?—A Cross-Sectional Mixed-Methods Study in Baden-Württemberg, Germany, to Explore General Practitioner Perspectives on Delabeling Potential in Primary Care

Antibiotics
Background: Most penicillin allergy labels are documented in early childhood and result from events of low risk for allergy. In Germany, evidence-based strategies to evaluate the likelihood of a true penicillin allergy are still lacking.
Regina Poß-Doering, Nicola A. Litke, Elham Khatamzas, Attila Altiner   +3 more
doaj   +1 more source

Light Emission from Ruthenium-Labeled Penicillins Signaling Their Hydrolysis by β-Lactamase

, 2016
Light Emission from Ruthenium-Labeled Penicillins Signaling Their Hydrolysis by β ...
Pam Liang (2997921), Mark T. Martin (2997924), Liwen Dong (2997927)   +2 more
core   +1 more source

Syphilis-Related Eye Disease Presenting as Bilateral Papilledema, Retinal Nerve Fiber Layer Hemorrhage, and Anterior Uveitis in a Penicillin-Allergic Patient [PDF]

, 2018
Jamie Dietze, Shane Havens
openalex   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Antibiotic Prescribing for Cellulitis in the Absence of Penicillin‐Cephalosporin Cross‐Reactivity Alerts: A Retrospective Study

Pharmacology Research & Perspectives
Cephalosporins are often avoided in patients with penicillin adverse drug reaction (ADR) labels. In our institution's electronic medication management system, penicillin and cephalosporin ADR labels do not generate cross‐reactivity alerts.
Milan Sundermann, James A. H. Mehrtens, Nicholas M. Douglas, Sharon J. Gardiner, Matthew Doogue, Paul K. L. Chin   +5 more
doaj   +1 more source

Indications and prescriptions of penicillins in a population of Colombia: A cross-sectional study

Brazilian Journal of Infectious Diseases
Inappropriate use of antibiotics plays a key role in increasing bacterial resistance. The aim was to determine the prescription patterns and approved and unapproved indications for the use of penicillins in a group of patients from Colombia.
Luis Fernando Valladales-Restrepo, Brayan Stiven Aristizábal-Carmona, Luisa María Londoño-Toro, Mariavictoria del Valle Jaramillo-Lima, Mariana Osorno-Ríos, Jorge Enrique Machado-Alba   +5 more
doaj   +1 more source

A Basic Overview of Penicillins and Their Use in Small Animal Medicine

, 1985
There are many factors to consider when deciding upon antimicrobial therapy. Some of them are suspected etiology, host status, organ system affected, and the properties of the drug being considered. Microbicidal drugs, such as penicillin, are superior to
Ames, Janel
core