Results 101 to 110 of about 170,743 (345)

Commonly prescribed β-lactam antibiotics induce C. trachomatis persistence/stress in culture at physiologically relevant concentrations.

Frontiers in Cellular and Infection Microbiology, 2014
Chlamydia trachomatis, the most common bacterial sexually transmitted disease agent worldwide, enters a viable, non-dividing and non-infectious state (historically termed persistence and more recently referred to as the chlamydial stress response) when ...
Jennifer eKintner, Dawn eLajoie, Jennifer eHall, Judy eWhittimore, Robert V Schoborg   +4 more
doaj   +1 more source

Two-dimensional gel electrophoresis and immunoblotting of human serum albumin modified by reaction with penicillins

, 1995
A two‐dimensional gel electrophoresis and immunoblotting procedure has been developed to assess the level of modification by penicillins in human serum albumin.
PALLINI V., MAGI B., MASSIDDA, ORIETTA, Rossolini, A., Marzocchi, Barbara, Magi, Barbara, ROSSOLINI A., Bini, Luca, Massidda, O., Pallini, V., MARZOCCHI B., Cellesi, C., BINI L., CELLESI C.   +13 more
core   +1 more source

Toxicity of the Penicillins [PDF]

Postgraduate Medical Journal, 1964
THE absence of direct toxicity is one of the most remarkable properties of the penicillin molecule; that is to say, the penicillin molecule as we know it and as we should use it. If you try hard enough, you can make it toxic by altering it or abusing it, as I shall try to show later.
openaire   +2 more sources

Hydrogen bonding and protein perturbation in β-lactam acyl-enzymes of Streptococcus pneumoniae penicillin-binding protein PBP2x [PDF]

, 1999
R. S. Chittock, Simon Ward, Alan Wilkinson, Patrick Caspers, Barbara MENSCH, Malcolm G. P. Page, Christopher W. Wharton   +6 more
openalex   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Analysis of antibacterial agents consumption in a Brazilian southeastern hospital complex from 2018 to 2021 [PDF]

Brazilian Journal of Pharmaceutical Sciences
Healthcare during the COVID-19 pandemic may have led to the inappropriate use of antimicrobial agents and contributed to elevated multidrug resistance.
Giuliana Amanda de Oliveira, Adriano Max Moreira Reis   +1 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Dephthaloylation of Phthalimido-Containing Cephalosporins and Penicillins

, 1977
Dephthaloylation of phthalimido functionalized cephalosporins and penicillins via the corresponding phthalisoimides was performed.
S. Kukolja, S. R. Lammert, A. I. Ellis, Kukolja, S., Lammert, S. R., Ellis, A. I.   +5 more
core  

Evaluation of Beta-lactam antibacterials and penicillins consumption [PDF]

, 2016
Background: The beta-lactam family of antibiotics includes the majority of the most heavily used antibacterials in clinical medicine. They are important, both historically and currently, because of their effectiveness and generally low toxicity.
Bernaz, Emilian P.
core  

Reaction of soluble penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus with β-lactams and acyclic substrates: kinetics in homogeneous solution [PDF]

, 1998
Karen Graves-Woodward, R. F. Pratt
openalex   +1 more source