Results 91 to 100 of about 170,743 (345)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
, 2008 This chapter outlines selected recent developments, together with some reminders of traditional methods, in the chemistry of penams A (4-thia-1-azabicyclo[3.2.0]heptan-7-one) and penems B (4-thia-1-azabicyclo[3.2.0]hept-2-en-7-one).
Brulé, Cédric +1 more
core
FAST ATOM BOMBARDMENT MASS SPECTROMETRY OF 14 PENICILLINS [PDF]
, 1991 Fast atom bombardment (FAB) mass spectra of 14 penicillins have been presented and their fragmentation pathways have been analyzed in both positive and negative modes.
Iwata, Masaya +5 more
core
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Revista Científica, 2014 Â One of the main problems concerning the determination of residues of penicillins (PENs) in complex matrix, as milk samples of animal origin, is the sample treatment. The aim of this work was to evaluate the influence of different background electrolyte
María Ysabel Piñero +4 more
doaj
Penicillin Allergy: The Impact of a False Diagnosis
Acta Médica Portuguesa, 2019 N/a.
Bárbara Kong Cardoso +5 more
doaj +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Population-level transition of capsular polysaccharide types among sequence type 1 group B Streptococcus isolates with reduced penicillin susceptibility during a long-term hospital epidemic [PDF]
, 2018 Noriyuki Nagano +9 more
openalex +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source