Results 91 to 100 of about 36,910 (309)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

A Basic Overview of Penicillins and Their Use in Small Animal Medicine [PDF]

open access: yes, 1985
There are many factors to consider when deciding upon antimicrobial therapy. Some of them are suspected etiology, host status, organ system affected, and the properties of the drug being considered. Microbicidal drugs, such as penicillin, are superior to
Ames, Janel
core   +1 more source

Ionisation Constants of Some Penicillins and of their Alkaline and Penicillinase Hydrolysis Products [PDF]

open access: yes, 1963
Ionisation constants of several penicillins and of 6-aminopenicillanic acid in water at 25°, and approximate ionisation constants of the products of alkaline and penicillinase hydrolysis of some penicillins, are presented.
A E Bird, H D C Rapson
core   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

FAST ATOM BOMBARDMENT MASS SPECTROMETRY OF 14 PENICILLINS [PDF]

open access: yes, 1991
Fast atom bombardment (FAB) mass spectra of 14 penicillins have been presented and their fragmentation pathways have been analyzed in both positive and negative modes.
Iwata, Masaya   +5 more
core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

THE CONCENTRATIONS OF PENICILLINS IN THE CEREBROSPINAL FLUID AND BRAIN OF RABBITS WITH EXPERIMENTAL MENINGITIS [PDF]

open access: yes, 1965
The selection of an antibiotic to treat purulent meningitis is based upon the minimal inhibitory concentration of the drug for the infecting organism and the concentration of the antibiotic in the blood and cerebrospinal fluid following systemic ...
John Ruedy
core   +1 more source

Penicillin Allergy: The Impact of a False Diagnosis

open access: yesActa Médica Portuguesa, 2019
N/a.
Bárbara Kong Cardoso   +5 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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