Total Synthesis of Sacrolide A and Cytotoxic Evaluation
European Journal of Organic Chemistry, Volume 29, Issue 27, 17 July 2026.Isolated from the edible cyanobacterium Aphanothece sacrum, sacrolide A is a highly potent antimicrobial and cytotoxic metabolite. Its total synthesis via a convergent strategy enabled accurate assessment of its effects on liver and colon cells, offering new insights into its bioactivity and potential health risks.
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