Results 101 to 110 of about 4,583,036 (340)

Penile cancer: a Brazilian consensus statement for low- and middle-income countries

Journal of Cancer Research and Clinical Oncology, 2020
Penile cancer is highly prevalent in low- and middle-income countries, with significant morbidity and mortality rates. The first Brazilian consensus provides support to improve penile cancer patients’ outcomes, based on expert’s opinion and evidence from
A. Soares, Í. T. de Carvalho, A. G. da Fonseca, A. M. Alencar, Carlos Leite, D. Bastos, João Paulo Holanda Soares, K. Leite, Mário Ronalsa Brandão Filho, R. Coelho, S. Cavallero, Stênio de Cássio Zequi, José de Ribamar Rodrigues Calixto   +12 more
semanticscholar   +1 more source

Peptide Amphiphiles Hitchhike on Endogenous Biomolecules for Enhanced Cancer Imaging and Therapy

Advanced Materials, EarlyView.
Weakly assembled peptide amphiphile nanostructures disassemble in circulation and reassemble with blood biomolecules, mainly lipoproteins. Binding to blood biomolecules prolongs blood circulation and improves accumulation in solid tumors. In the tumor microenvironment, peptide amphiphiles assemble with cholesterol‐rich domains of cell membranes ...
Li Xiang, Morgan R. Stewart, Kailin Mooney, Mingchong Dai, Samuel Drennan, Samantha Holland, Arnaud Quentel, Sinan Sabuncu, Benjamin R. Kingston, Isabel J. Dengos, Karla Bonic, Florian Goncalves, Xin Yi, Michael I. Henderson, Srivathsan Ranganathan, Bruce P. Branchaud, Leslie L. Muldoon, Ramon F. Barajas Jr, Jared M. Fischer, Adem Yildirim   +19 more
wiley   +1 more source

Sustainable Liquid Metal Composites for Soft Electronics and E‐Waste Reduction

Advanced Materials, EarlyView.
Liquid metal (LM) composites embody recyclability, repairability, renewability, and resilience (4R), offering a sustainable route for soft electronics. With exceptional conductivity, stretchability, and eco‐friendly recovery, these systems enable closed‐loop lifecycles and reduce e‐waste.
Abdollah Hajalilou, Elahe Parvini, Carmel Majidi   +2 more
wiley   +1 more source

PENILE CANCER AND MULTIPLE PREPUTIAL STONE: A RARE CASE REPORT

Jurnal Urologi Indonesia
Objective: This paper aims to report a case of penile cancer with multiple prepuce stones in a 46-year-old non-circumcised male. Case Presentation: A 46-year-old male patient came to the clinic with complaints of a slowly enlarging penis since the last ...
Abdul Munawwir, Teddy Yonatha
doaj   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

FLIP: Transforming Consumer Projectors into Maskless Microscale Photopatterning Tools via Fresnel Lens Integration

Advanced Materials Technologies, EarlyView.
A low‐cost, maskless visible light photopatterning system has been developed by combining a consumer‐grade projector with a single Fresnel lens, generating the Fresnel Lens Integrated Projector (FLIP) system. FLIP enables flexible photopatterning of solid and gel films with features down to 30 µm and 135 µm, respectively.
Sridaran Rajagopal, Sofia Arshavsky‐Graham, Govind Kaigala   +2 more
wiley   +1 more source

Penile Carcinoma: Risk Factors and Molecular Alterations

The Scientific World Journal, 2011
Penile carcinoma is a rare, male cancer. Although the incidence of penile carcinoma is very low in Western countries, in some countries, the incidence is significantly greater, with penile carcinoma accounting for ≤10% of all male malignancies.
Marilia F. Calmon, Mânlio Tasso Mota, José Vassallo, Paula Rahal   +3 more
doaj   +1 more source

Minimally Invasive Chemical Biopsy Needle with Self‐Wettable Extraction Phase For In Vivo Tissue Sampling During Medical Procedures

Advanced Science, EarlyView.
A new tissue sampling device using an acupuncture needle with bio‐compatible extraction sorbents in the recessed section is developed. The coating material using self‐wettable particles doesn't require solvent activation after sterilization. This device is applied for the anti‐cancer drug concentration monitoring during the in vivo lung perfusion ...
Runshan Will Jiang, Wei Zhou, Marcelo Cypel, Todd L. Demmy, Gal Shafirstein, Guillermo Garza, Emily Gawrys, Joanna Bogusiewicz, Barbara Bojko, Janusz Pawliszyn   +9 more
wiley   +1 more source

Discovery of a Potent and Selective TEAD Degrader with Durable Degradation Activity

Advanced Science, EarlyView.
KG‐FP‐003, a highly potent TEAD‐YAP PROTAC derived from the patented inhibitor is developed. It selectively degrades endogenous TEAD proteins in HiBiT systems without IMiD‐related off‐target effects. Screening across 867 cancer cell lines revealed broad and superior anti‐tumor activity, highlighting its therapeutic potential through targeted TEAD ...
Linhui Cao, Jing Yang, Yuhang Liu, Xiaotong Chen, Yufang Shi, Yunshuo Zhao, Yong Zhang, Jian Chen, Bowen Li, Wuqiang Wen, Lu Chen, Bo Peng, Lu Huang, Yanli Sun, Lixin Zhou, Matthew G Rees, Melissa M Ronan, Jennifer A Roth, Zhixiang Guo, Jing Xing, Guangya Zhu, Yazhou Wang, Baishan Jiang, Jing Lu, Kehao Zhao, Wenchao Lu   +25 more
wiley   +1 more source

Peptide Electrostatic Modulation Directs Human Neural Cell Fate

Advanced Science, EarlyView.
This study explores the effect of charge on the bioactivity of peptide‐based supramolecular materials. The design of a peptide library with varying charges that self‐assemble into supramolecular fibers is presented, demonstrating how the surface charge of these fibers, used as artificial extracellular matrices, influences the fate of human neural ...
Laura Perez‐Chirinos, Xavier Barceló, M. Gabriella Chiariello, Irene Sanz, Amaia Iturrospe, Arantxa Arbe, J. Alberto Ortega, Siewert J. Marrink, Aitziber L. Cortajarena, Zaida Álvarez, Ivan R. Sasselli   +10 more
wiley   +1 more source