Results 261 to 270 of about 43,593 (360)

Compressive Forces Induce Epigenetic Activation of Aged Human Dermal Fibroblasts Through ERK Signaling Pathway

open access: yesAging Cell, EarlyView.
Direct activation and rejuvenation of aged fibroblasts through the application of mechanical forces in a 3D spheroid culture model. The ERK signaling pathway was revealed as a key underlying mechanism. ABSTRACT Age‐related changes in human dermal fibroblasts (HDFs) contribute to impaired wound healing and skin aging.
Hui Liu   +4 more
wiley   +1 more source

Epidemiology of penile cancer in Poland compared to other European countries. [PDF]

open access: yesCancer Med
Wnętrzak I   +6 more
europepmc   +1 more source

Age‐Dependent Regulation of Hippocampal Inflammation by the Mitochondrial Translocator Protein in Mice

open access: yesAging Cell, EarlyView.
The role of mitochondrial translocator protein (TSPO) in hippocampal inflammation is age‐dependent, with TSPO deletion drastically exacerbating inflammation in aged mice, while dampening it in young mice. This TSPO–aging interaction was linked to NF‐kβ and interferon regulatory transcriptional networks. TSPO deletion exacerbated age‐dependent depletion
Kei Onn Lai   +7 more
wiley   +1 more source

Human papillomavirus (HPV) and Epstein-Barr virus (EBV) in Penile Cancer in Thailand. [PDF]

open access: yesAsian Pac J Cancer Prev
Sangkhamanon S   +7 more
europepmc   +1 more source

Local and Systemic Effects of Chronic Intracavernous Injection of Papaverine, Prostaglandine E1 and Saline in Primates [PDF]

open access: yes, 1989
Aboseif, Sherif R.   +7 more
core  

Detection of lymph node metastases in penile cancer [PDF]

open access: green, 2018
Jonathan Bloom   +4 more
openalex   +1 more source

Identifying Age‐Modulating Compounds Using a Novel Computational Framework for Evaluating Transcriptional Age

open access: yesAging Cell, EarlyView.
RNAge is a transcriptional based computational approach to measure changes in cellular age upon experimental manipulation. In silico screening of a database of transcriptional changes from drug perturbations identified a novel aging agent that was applied to an hPSC model of neurodegenerative disease to trigger a late‐onset phenotype.
Chao Zhang   +8 more
wiley   +1 more source

Exploring the Multifactorial Landscape of Penile Cancer: A Comprehensive Analysis of Risk Factors. [PDF]

open access: yesDiagnostics (Basel)
Amicuzi U   +26 more
europepmc   +1 more source

Regulation of the MAPK/ERK Pathway by miRNA‐27b in Gastric Cancer: Diagnostic Implications and Therapeutic Potential of Aloin

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
ABSTRACT Background Globally, gastric cancer (GC) ranks as the fourth most deadly and fifth most prevalent kind of cancer. Appropriate treatment methods, precise etiology, and molecular processes of GC are still unclear. Methods In silico and quantitative real‐time reverse transcription polymerase chain reaction (qRT‐PCR)‐based expression of miRNA‐27b ...
Yang Dehuo, Wang Ying, Cao Lin
wiley   +1 more source

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