Results 51 to 60 of about 4,480,053 (377)
Impact of Examined Lymph Node Count and Lymph Node Density on Overall Survival of Penile Cancer
Background Few studies have explored the optimal examined lymph node count and lymph node density cutoff values that could be used to predict the survival of patients with penile cancer.
Pan Gao+5 more
semanticscholar +1 more source
Renal Subcapsular xenografing of human fetal external genital tissue - A new model for investigating urethral development. [PDF]
In this paper, we introduce our novel renal subcapsular xenograft model for the study of human penile urethral and clitoral development. We grafted fifteen intact fetal penes and clitorides 8-11 weeks fetal age under the renal capsules of gonadectomized ...
Baskin, Laurence+6 more
core +2 more sources
Penile cancer trends and economic burden in the Brazilian public health system
Objective: To gather information on penile cancer epidemiologic trends and its economic impact on the Brazilian Public Health System across the last 25 years.
Fernando Korkes+6 more
doaj +2 more sources
Changing Radiotherapy Paradigms in Penile Cancer
Radiation therapy (RT) has not been prominent in the treatment of penile cancer because of poorly reproducible results when used in the adjuvant setting.
Peter A.S. Johnstone+6 more
doaj
Primary prevention and vaccination for penile cancer
The outcome of penile cancer is proportional to the stage at presentation. Strategies aimed at primary prevention would have a clear advantage, both for the individual and in terms of health economics. A number of preventative measures could be employed,
Majid Shabbir+3 more
doaj +1 more source
Conducting interviews about penile cancer: A patient-conducted-interview study [PDF]
Objectives: Penile cancer is a rare but destructive condition. It has been found to be detrimental to body image, general health and sexual functioning, while increasing anxiety and social problems.
Branney, P, Eardley, I, Witty, K
core
Update in the management of penile cancer [PDF]
The management of penile cancer has evolved as less invasive techniques are applied in the treatment of the primary tumor and inguinal lymph nodes.Herein we review the literature focusing on advances in the preservation of the phallus as well as less morbid procedures to evaluate and treat the groins.Promising imaging modalities for staging are ...
Caso, Jorge R.+3 more
openaire +5 more sources
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam+10 more
wiley +1 more source
Dynamic sentinel lymph node biopsy (DSNB) and radical inguinal lymph node dissection (ILND) are important in the management of penile cancer patients, but high-level evidence for preoperative, perioperative, and postoperative management remains scarce ...
Christian D. Fankhauser+7 more
doaj