Results 71 to 80 of about 4,583,036 (340)

Current and Future Strategies in the Diagnosis and Management of Penile Cancer

open access: yesAdvances in Urology, 2011
Penile cancer is an uncommon malignancy that has a devastating effect on the patient while also being challenging to diagnose and treat. By implementing preventive measures, we can decrease the incidence of this disease and improve the quality of life of
Samuel M. Lawindy   +3 more
doaj   +1 more source

Penile cancer with positive nodes: A case of HPV p16-positivity and its significance, implication of data from head and neck cancer

open access: yesUrology Case Reports, 2019
Penile cancer is normally discovered in an early stage due to its visibility to the patient. This case report demonstrates a morbidly obese patient with a locally advanced penile cancer hidden by fatty tissue.
Cam Nguyen   +5 more
doaj   +1 more source

Evaluation of the Guidelines for Penile Cancer Treatment: Overview and Assessment

open access: yesSociété Internationale d’Urologie Journal, 2021
IntroductionMedical organizations have provided evidence-based guidelines for penile cancer treatment. This current review aims to compare and appraise guidelines on penile cancer treatment to provide a useful summary for clinicians.
Abdulmajeed Aydh, Shahrokh F. Shariat, Reza Sari Motlagh, Ekaterina Laukhtina, Fahad Quhal, Keiichiro Mori, Hadi Mostafaei, Andrea Necchi, Benjamin Pradere
doaj   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

open access: yesAdvanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers   +10 more
wiley   +1 more source

Prognostic value of systemic inflammatory factors NLR, LMR, PLR and LDH in penile cancer [PDF]

open access: gold, 2020
Chen Hu   +11 more
openalex   +3 more sources

A Vascularized Microphysiological System Reproducing Endochondral Ossification in Vitro to Study Ewing Sarcoma Proliferation and Migration

open access: yesAdvanced Functional Materials, EarlyView.
A biofabricated 3D in vitro model recapitulating endochondral ossification (ECO) is described, mimicking the steps from condensation to chondrogenesis and hypertrophy, culminating with vascularization of the hypertrophic construct. As a model proof of concept application, Ewing Sarcoma cells are seeded in the model, showing modifications in their ...
Maria Vittoria Colombo   +13 more
wiley   +1 more source

Human papillomavirus genotype prevalence in invasive penile cancers from a registry-based United States population

open access: yesFrontiers in Oncology, 2014
Background. Human papillomavirus (HPV) is estimated to play an etiologic role in 40%-50% of penile cancers worldwide. Estimates of HPV prevalence in U.S. penile cancer cases are limited. Methods.
Brenda Y Hernandez   +16 more
doaj   +1 more source

Neoadjuvant chemotherapy and penile conservation in the management of Buschke – Lowenstein tumor, a case report

open access: yesUrology Case Reports, 2020
Buschke-Lowenstein tumor is a rare form of low-grade penile cancer. Its low prevalence amongst the population bars the establishment of a standardized treatment algorithm.
Anthony El Khoury   +2 more
doaj   +1 more source

Plasma‐Treated Hydrogel for Combined RONS and Chemotherapy Delivery: A Proof‐of‐Concept In Ovo

open access: yesAdvanced Functional Materials, EarlyView.
This study explores plasma‐treated hydrogels (PTH) as a new way to deliver both reactive oxygen and nitrogen species and chemotherapy (Doxorubicin) directly to tumors. In ovo tests show effects after a single dose, especially in osteosarcoma tumors. Tumor weight decrease, and a resistance‐related protein is reduced.
Milica Živanić   +9 more
wiley   +1 more source

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

open access: yesHepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam   +10 more
wiley   +1 more source

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