Results 71 to 80 of about 43,593 (360)
Objective Posttraumatic osteoarthritis (PTOA) accounts for nearly 12% of osteoarthritis incidences and often occurs after anterior cruciate ligament (ACL) tear. Ensuring the uptake of preventive treatments for PTOA requires that investigators and clinicians understand factors influencing patients to seek preventive therapies.
Lily M. Waddell+10 more
wiley +1 more source
TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam+10 more
wiley +1 more source
Predictive genomics: A cancer hallmark network framework for predicting tumor clinical phenotypes using genome sequencing data [PDF]
We discuss a cancer hallmark network framework for modelling genome-sequencing data to predict cancer clonal evolution and associated clinical phenotypes. Strategies of using this framework in conjunction with genome sequencing data in an attempt to predict personalized drug targets, drug resistance, and metastasis for a cancer patient, as well as ...
arxiv +1 more source
Cell Membrane Vesicle Camouflaged Artificial Cells
Artificial cells camouflaged with a cell membrane vesicle coating are able to assemble into synthetic aggregates that exhibit rudimentary communication capabilities. Additionally, when these artificial cells are equipped with antioxidant capabilities, they are able to protect the intracellular homeostasis in HepG2 cells present in semi‐synthetic ...
Paula De Dios Andres+11 more
wiley +1 more source
Penile nodule with inguinal lymphadenopathy: Prostatic adenocarcinoma masquerading as penile cancer
Although anatomically the penis is closely related to the prostate, penile metastasis from prostate cancer is an uncommon phenomenon. These patients usually present late in the course of the disease with wide spread metastasis.
Bastab Ghosh+3 more
doaj +1 more source
Penile cancer after a tick bite: A possible association
Penile cancer is a rare cancer in Western countries, but is more common in parts of the developing world. Usually, it is associated with older uncircumcised men who have a long-term phymotic preputium.
Ognen Ivanovski+6 more
doaj +1 more source
A visible light‐responsive polyacrylamide‐azobenzene hydrogel enables safe, reversible stiffness control for studying cell mechanobiology without harmful UV exposure. This approach reveals stem cells respond rapidly to mechanical changes, showing altered shape and protein distribution within one hour.
Aafreen Ansari+11 more
wiley +1 more source
Abstract Objectives To compare national and international guidelines regarding sentinel lymph node (SLN) mapping in endometrial cancer. Methods A descriptive comparative study of the National Comprehensive Cancer Network (NCCN), the Society of Gynecologic Oncology (SGO), the European Society of Gynecological Oncology (ESGO), the British Gynecological ...
Aharon Dick+5 more
wiley +1 more source
Diagnosis and management of premalignant penile lesions
Diagnosing premalignant penile lesions from benign penile dermatoses presents a unique challenge. The rarity of these conditions and the low incidence of penile cancer mean that the majority of our knowledge is based on small, non-randomized ...
Majid Shabbir, Suks Minhas, Asif Muneer
doaj +1 more source