Results 91 to 100 of about 10,406,114 (352)

Penile Mondor’s Disease: Long-Term Functional Follow-Up

open access: yesUrology Journal, 2012
No ...
Rafael Boscolo-Berto   +1 more
doaj  

Penile carcinoma: what dermatologists need to know

open access: yesRevista da Sociedade Portuguesa de Dermatologia e Venereologia, 2023
Penile cancer is a rare disease in developed countries and is frequently underrecognized by clinicians leading to delays in diagnosis and treatment. Squamous cell carcinoma (SCC) is the predominant pathological entity, representing 95% of all penile ...
Maria J. Guimarães   +3 more
doaj  

Bilateral fracture of corpora cavernosa with complete rupture of the anterior urethra: Case report and review of recent findings for surgical management

open access: yesRevista de la Facultad de Medicina, 2018
Introduction: Penile fracture is a rare urological emergency associated in up to 30% of cases with injury to the anterior urethra. Recent data suggest that early surgical intervention is the best treatment strategy.
David Andrés Castañeda-Millán   +3 more
doaj   +1 more source

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

open access: yesAdvanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang   +12 more
wiley   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

open access: yesAdvanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi   +13 more
wiley   +1 more source

Clinical Results of Penile Prosthesis Implantation for Treating Organic Erectile Dysfunction

open access: yesİstanbul Medical Journal, 2016
Introduction: This study aimed to evaluate the clinical results of penile prosthesis implantation for treating patients with organic erectile dysfunction (ED).Methods: Between January 2006 and December 2015, medical records of penile prosthesis ...
Mustafa Kadıhasanoğlu   +4 more
doaj   +1 more source

Genomic copy number variation association study in Caucasian patients with nonsyndromic cryptorchidism [PDF]

open access: yes, 2016
Copy number variation (CNV) is a potential contributing factor to many genetic diseases. Here we investigated the potential association of CNV with nonsyndromic cryptorchidism, the most common male congenital genitourinary defect, in a Caucasian ...
Abrams, Debra J.   +17 more
core   +1 more source

FASLG Derived from Fibroblasts in Hydroxyapatite‐Rich Microenvironment Induces Urothelial Anoikis to Trigger Randall's Plaque Exposure

open access: yesAdvanced Science, EarlyView.
Randall's plaques (RP) serve as the nidus for calcium oxalate (CaOx) kidney stones. The current study reveals that hydroxyapatite (HAP) crystals activate the THY1–GSK3α/β–β‐catenin axis in renal interstitial fibroblasts (hRIFs), inducing FASLG secretion.
Minghui Liu   +14 more
wiley   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

open access: yesAdvanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li   +25 more
wiley   +1 more source

Genital myiasis associated with genital piercing. Case report

open access: yesSão Paulo Medical Journal, 2017
CONTEXT: Myiasis is caused by larval infestation that usually occurs in exposed wounds. Dermatobia hominis is the most common fly species responsible for this parasitic infection. Genital piercing is an ornamental practice used in certain social circles.
Daniel Melecchi Freitas   +3 more
doaj   +1 more source

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