Results 161 to 170 of about 349,677 (327)

Association of bi‐parametric MRI measures with continence after robot‐assisted radical prostatectomy

open access: yesBJU International, Volume 135, Issue 4, Page 603-610, April 2025.
Objective To investigate the association between pre‐ and postoperative magnetic resonance imaging (MRI) measurements of the membranous urethra and the prostate volume and continence following robot‐assisted radical prostatectomy (RARP). Patients and Methods From December 2018 to June 2022, 100 continent patients undergoing unilateral nerve‐sparing or ...
Alexander B. Nolsøe   +8 more
wiley   +1 more source

Intracardiac metastasis of squamous cell carcinoma of the penis

open access: yesAutopsy and Case Reports, 2013
Penile cancer shows variable incidence in different countries with a higher prevalence in developing countries. Squamous cell carcinoma represents the most common histologic type.
Sheila Aparecida Coelho Siqueira   +1 more
doaj  

Dysmorphic neurons express markers of inhibitory glycinergic signaling in focal cortical dysplasia IIb

open access: yesBrain Pathology, EarlyView.
Deep learning tissue mapping can guide region of interest selection for spatial transcriptomic analyses. Using this method, a transcriptional catalogue of focal cortical dysplasia type IIb was generated, revealing enrichment for markers of inhibitory glycinergic signaling in cytomegalic dysmorphic neurons.
Ameesha Paliwal   +8 more
wiley   +1 more source

A complex network perspective on brain disease

open access: yesBiological Reviews, EarlyView.
ABSTRACT If brain anatomy and dynamics have a complex network structure as it has become standard to posit, it is reasonable to assume that such a structure should play a key role not only in brain function but also in brain dysfunction. However, exactly how network structure is implicated in brain damage and whether at least some pathologies can be ...
David Papo, Javier M. Buldú
wiley   +1 more source

Fraternal cooperation of hierarchical cancer parallels metazoan multicellularity and eusociality

open access: yesBiological Reviews, EarlyView.
ABSTRACT Metazoan multicellularity and eusociality — both outcomes of the fraternal major transitions — have numerous features in common such as uneven distribution of group‐establishing potential. In addition to this framework, I argue herein that the group‐forming principles of metazoan multicellularity and eusociality are analogous to hierarchical ...
Jibeom Choi
wiley   +1 more source

Mixed Gonadal Dysgenesis: A Comprehensive Review of Clinical Spectrum, Diagnostic Strategies, and Management Approaches

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Background Mixed gonadal dysgenesis (MGD) is a rare form of differences in sex development (DSD) typically associated with 45,X/46,XY mosaicism. The phenotypic presentation of MGD varies from atypical genitalia to typical male or female appearances often associated with Turner stigmata.
Dinesh Giri   +6 more
wiley   +1 more source

Prevalence and Associated Factors of Olfactory and Gustatory Loss in Patients With Nasal Septal Deviation

open access: yesClinical Otolaryngology, EarlyView.
ABSTRACT Objectives This study aimed to evaluate the olfactory and gustatory functions of patients with nasal septal deviation (NSD) and identify the factors associated with olfactory loss (OL) and gustatory loss (GL). Design and Setting Retrospective data analysis of cohort group. Participants Two‐hundred fourteen adult patients with NSD at a tertiary
Ja‐Yoon Kim   +3 more
wiley   +1 more source

Synergistic associations of metformin and GLP‐1 receptor agonist use with adiposity‐related cancer incidence in people living with type 2 diabetes

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Background Metformin and glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) may reduce the risk of adiposity‐related cancers in patients with type 2 diabetes (T2D). The potential synergistic effects of these treatments on cancer incidence remain unclear, considering their distinct biological mechanisms and their associated effects on body ...
Alex E. Henney   +6 more
wiley   +1 more source

Safety and efficacy of the therapy with CD4 + CD25highCD127‐T regulatory cells: When paediatric patient becomes adult

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aim CD4 + CD25highCD127‐T regulatory cells (Tregs) remain a drug candidate for immunotherapy of type 1 diabetes. We completed three trials testing Tregs in recently diagnosed type 1 diabetes children. Here, we looked for long‐term safety and efficacy aspects important in the authorisation of this therapy.
Marta Bandura   +18 more
wiley   +1 more source

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