Results 71 to 80 of about 11,733 (324)

Conditioned Media from Mechanically Stimulated Macrophages Upregulate Osteogenic Genes in Human Mesenchymal Stromal Cells

Advanced Healthcare Materials, EarlyView.
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex, Ursula Menzel, Yann Ladner, Angela R. Armiento, Martin J. Stoddart   +4 more
wiley   +1 more source

Immune checkpoint blockade with anti-programmed cell death 1 (PD-1) monoclonal antibody (mAb) cemiplimab: ongoing and future perspectives in rare genital cancers treatment

Journal for ImmunoTherapy of Cancer, 2022
Cemiplimab is a highly potent, hinge-stabilized human IgG4 monoclonal antibody (mAb) targeting programmed cell death 1 (PD-1) receptor approved for patients with locally advanced or metastatic cutaneous squamous cell carcinoma (SCC) who are not ...
Lorenzo Antonuzzo, Sara Fancelli, Maria Cristina Petrella, Elisabetta Gambale, Enrico Caliman, Laura Doni, Serena Pillozzi   +6 more
doaj   +1 more source

Penile rehabilitation for post-prostatectomy erectile dysfunction [PDF]

, 2016
The objectives are as follows: To assess the effects of penile rehabilitation interventions for post-prostatectomy erectile ...
Alemozaffar, Bolland, Burnett, Burnett, Egger, Elbourne, Fode, Fowler, Gebert, Goluboff, Guyatt, Hatzimouratidis, Heidenreich, Higgins, Higgins, Jemal, Jüni, Kacker, Kendirci, Kubin, Kundu, Lalong-Muh, Liberati, Lowrance, Mulhall, Mulhall, NIH Consensus, Penson, Rabbani, Raina, Rozet, Segal, Stanford, Steggall, Sterne, Weyne, Wood, Zippe   +37 more
core   +2 more sources

Rolling Ultrasharp Microneedle Spheres Enable Topical Delivery of Biologics Through the Skin

Advanced Healthcare Materials, EarlyView.
Rolling ultraminiaturized microneedle spheres (RUMS), created via two‐photon polymerization, unlock effective and painless topical delivery of messenger RNA (mRNA) and drugs through the skin. By gently forming thousands of microscopic pores, RUMS boost skin permeability by up to 100‐fold.
Theocharis Nikiforos Iordanidis, Argyris Spyrou, Samantha Roudi, Fredrik J. Swartling, Göran Stemme, Samir EL Andaloussi, Niclas Roxhed   +6 more
wiley   +1 more source

Reproductive tract biology: Of mice and men. [PDF]

, 2019
The study of male and female reproductive tract development requires expertise in two separate disciplines, developmental biology and endocrinology.
Baskin, Laurence S, Cao, Mei, Cunha, Gerald R, Ricke, Will A, Robboy, Stanley J, Sinclair, Adriane   +5 more
core  

Bone‐Derived dECM Hydrogels Support Tunable Microenvironments for In Vitro Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
A tunable methacrylated decellularized bone matrix hydrogel (dECM‐MA) is developed to support 3D culture of human osteoblasts. The hydrogel preserves bone‐specific ECM cues and allows precise control over mechanical properties. This system provides a customizable platform for studying osteogenic differentiation and modeling bone tissue environments for
Minne Dekker, Luke Hipwood, Akhilandeshwari Ravichandran, Dietmar W. Hutmacher, Christoph Meinert, Jacqui McGovern   +5 more
wiley   +1 more source

Interventions for sexual dysfunction following treatments for cancer in women [PDF]

, 2016
BACKGROUND: The proportion of people living with and surviving cancer is growing. This has led to increased awareness of the importance of quality of life, including sexual function, in those affected by cancer.
Candy, B, Jones, L, King, M, Tookman, A, Vickerstaff, V   +4 more
core   +1 more source

Human Endometrial Extracellular Matrix Hydrogel Facilitated Endometrial Mesenchymal Stem Cells for Endometrial Regeneration

Advanced Healthcare Materials, EarlyView.
Adequate thickness of the uterine lining is crucial for women with thin or damaged endometrium to achieve pregnancies. Endometrial mesenchymal stem cells (eMSC) can facilitate the cyclical repair and regeneration of the human endometrium. In this study, the human endometrium derived extracellular matrix hydrogel supports the growth of eMSC promoting ...
Jingwen Xu, Philip C N Chiu, Ernest H Y Ng, Sentao Hu, Zi Ye, Liaobing Xin, Lie Ma, Songying Zhang, William S B Yeung, Rachel W S Chan   +9 more
wiley   +1 more source

The Report of Two Cases of Metastasis to the Corpora Covernosa from Transitional Cell Carcinoma of the Bladder

پزشکی بالینی ابن سینا, 1999
Tow cases were studied and followed. Both of the cases were diagnosed    as   having    secondary   metastasis  of   penis  ( Primary  cancer  in  urinary    bladder).      Both  cases  were  operated  by  T.U.R  technique.  Both  patients returned   
Hooshang Bab-Al-Havaejee
doaj  

Cirugía de Mohs: Aplicación de la técnica a neoplasias del pene [PDF]

Actas Urológicas Españolas, 2007
La cirugía de Mohs es una técnica quirúrgica que permite la extirpación en capas de tumores cutáneos con los más elevados porcentajes de curación. Al mismo tiempo permite el máximo ahorro de tejido sano. Todo ello es posible gracias a la supervisión microscópica que posibilita analizar el 100% de los bordes tumorales de cada una de las capas y así ...
Cuevas, J., de Eusebio, E., Díez, E., Castiñeira, I.   +3 more
openaire   +4 more sources