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Pennyroyal Oil Poisoning and Hepatotoxicity

JAMA - Journal of the American Medical Association, 1979
PENNYROYAL oil has been used in folklore medicine for many years as an abortifacient and as a means to induce menstruation.1Herbal medicine books currently in health food stores mention its use as an abortifacient and recommend its use for various minor ailments. We report two recent cases of pennyroyal oil ingestion for the purpose of abortion. One of
Barry H Rumack
exaly   +2 more sources

PENNYROYAL (MENTHA PULEGIUM) AND HART´S PENNYROYAL (MENTHA CERVINA) BIODIVERSITY IN ALENTEJO, PORTUGAL

Acta Horticulturae, 2006
Mentha pulegium and M. cervina are traditionally used in Alentejo to flavour fish and “açordas” recipes, as well as for medicinal purposes. The essential oil has also industrial applications in foods conservation. M. pulegium is still common in nature, but M. cervina has been disappearing due to excessive collection, overgrazing and habitat destruction.
Póvoa O   +7 more
openaire   +2 more sources

Pennyroyal oil toxicosis in a dog

Journal of the American Veterinary Medical Association, 1992
A dog was treated for fleas with the application of pennyroyal oil obtained by the owner at a health food store. Vomiting ensued within 2 hours, and despite emergency treatment, the dog died within 48 hours. At necropsy, pennyroyal oil was determined to be the cause of death.
M, Sudekum   +3 more
openaire   +2 more sources

Mitigation of Pennyroyal Oil Hepatotoxicity in the Mouse

Academic Emergency Medicine, 2003
Abstract Objectives: Pennyroyal oil ingestion has been associated with severe hepatotoxicity and death. The primary constituent, R‐(+)‐pulegone, is metabolized via hepatic cytochrome P450 to toxic intermediates. The purpose of this study was to assess the ability of the specific cytochrome P450 inhibitors disulfiram and cimetidine to mitigate ...
Matthew D, Sztajnkrycer   +4 more
openaire   +2 more sources

Biological activities of pennyroyal (Mentha pulegium L.) in broilers

Livestock Science, 2012
Abstract This study was conducted to determine the effects of dietary pennyroyal (Mentha pulegium L.) levels (0, 0.25 or 0.50%) on the growth performance and Escherichia coli and lactic acid bacteria count in the jejunum of broilers. A total of 150 broiler chicks (Ross 308), obtained from a commercial hatchery at 1 day of age, were allocated to 3 ...
ÜRÜŞAN ALTUN, Hilal   +2 more
openaire   +2 more sources

Quantitative Determination of Pulegone in Pennyroyal Oil by FT-IR Spectroscopy

Journal of Agricultural and Food Chemistry, 2009
Pulegone constitutes a monoterpene occurring in Mentha species and primarily in Mentha pulegium L. (pennyroyal). A major source of human exposure to pulegone is the use of pennyroyal essential oil in flavorings, confectionery and cosmetics. The rapid quantification of pulegone in hydrodistilled pennyroyal oils (which were also "spiked" to increase the ...
Eleftherios A, Petrakis   +4 more
openaire   +2 more sources

Mathematical modelling and simulation of pennyroyal essential oil supercritical extraction

Chemical Engineering Science, 2000
Abstract Pennyroyal essential oil was isolated by supercritical fluid extraction and fractional separation. Extractions were performed at three different mean particle sizes (0.3, 0.5 and 0.7 mm) and three CO 2 flow rates (0.31, 0.43, and 0.62 g/s) and at p =100 bar and T =323 K. Essential oil yield was determined as a function of time. Yield data
REISVASCO E   +4 more
exaly   +3 more sources

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