Results 51 to 60 of about 448 (148)

Contrasting Reactivity of Fluoropyridines at Palladium and Platinum:  C−F Oxidative Addition at Palladium, P−C and C−F Activation at Platinum^†

, 2016
The divergent behavior of palladium(0) and platinum(0) is revealed in the reactivity of [M(PR3)2] (M = Pd or Pt; R = Cy or iPr) toward pentafluoropyridine and 2,3,5,6-tetrafluoropyridine.
Sascha Rothfeld (2699479), Naseralla A. Jasim (2169676), Hans-Georg Stammler (1549579), Joseph Izundu (2378497), Robin N. Perutz (1305213), Thomas Braun (269597), Beate Neumann (132351), Adrian C. Whitwood (1305204)   +7 more
core   +2 more sources

A mild method for the synthesis of a novel dehydrobutyrine-containing amino acid [PDF]

, 2014
Dehydrobutyrine is an amino acid that is present in a range of peptide natural products. Reaction of pentafluoropyridine with threonine and subsequent E1cb-type elimination allowed the preparation of novel dehydrobutyrine-containing amino acids under ...
Sandford, Graham, Webster, Alexandra M., Coxon, Christopher R., Kenwright, Alan M., Cobb, Steven L.   +4 more
core   +1 more source

Mechanism of the Catalytic Hydrodefluorination of Pentafluoropyridine by Group Six Triangular Cluster Hydrides Containing Phosphines: A Combined Experimental and Theoretical Study

, 2010
[EN] The catalytic hydrodefluorination (HDF) of pentafluoropyridine in the presence of arylsilanes is catalyzed by the tungsten and molybdenum(IV) cluster hydrides of formula [M3 S4 H3(dmpe)3] ¿, W-1¿for M = W and Mo-1¿for M = Mo (dmpe = 1,2-(bis ...
Mata Martínez, Jose A, Tomás F. Beltrán, Beltran, Tomas F., Marta Feliz, Jose A. Mata, Rosa Llusar, Vicent S. Safont., Llusar, Rosa, Mata, Jose A., Safont, Vicent S., Safont Villarreal, Vicent Sixte, Feliz Rodriguez, Marta, Beltrán Álvarez, Tomás Francisco   +12 more
core   +1 more source

Perfluoroheteroaromatics as Tools for Peptide Modification [PDF]

, 2018
The use of peptides as drugs has been hampered due to, in part, poor stability in vivo. To address this issue, heteroaromatics have been investigated in an attempt to improve enzymatic stability.
MOONEY, CAITLIN,ANNE
core   +1 more source

S‐Aryl Substitution Enhances Acidity of the 1,2,4‐Triazolium Scaffold

European Journal of Organic Chemistry, Volume 27, Issue 45, December 2, 2024.
A large series of novel N,N‐dialkyl‐1,2,4‐triazolium salts with 3‐S‐aryl substituents was prepared from neutral S‐aryl triazole precursors. High protofugalities (kinetic acidities) were demonstrated for C(5)‐H highlighting the acidifying effect of the distal C(3)‐sulfur with mechanistic insight obtained from XRD‐protofugality correlations. Abstract The
Matthew S. Smith, Toby J. Blundell, Ian Hickson, AnnMarie C. O'Donoghue   +3 more
wiley   +1 more source

Enhancing cycle life of nickel-rich LiNi0.9Co0.05Mn0.05O2 via a highly fluorinated electrolyte additive - pentafluoropyridine

, 2021
A highly fluorinated additive, pentafluoropyridine (PFP), is used here to enhance the interfacial stability of the Ni-rich LiNi0.9Co0.05Mn0.05O2 (NCM90) cathode at a cut-off voltage of 4.3 V vs. Li/Li+ at 30 °C.
Zhou, Ke, Zheng, Jianming, Zou, Yue, Jiao, Tianpeng, Zhang, Xiaozhen, Wu, Qilong, Chen, Xunxin, Liu, Gaopan, Yang, Yong   +8 more
core  

Synthesis and molecular structure of a perfluorinated pyridyl carbanion

, 2012
Reaction of pentafluoropyridine with sodium nitromethanide allowed the isolation and characterisation of the first perfluorinated pyridyl carbanion system, sodium nitrobis(perfluoropyridin-4-yl)methanide, by X-ray ...
Pohl, E., Colgin, N., Cobb, S.L., Tatum, N.J., Sandford, G.   +4 more
core   +1 more source

Rapid Intermolecular Carbon−Fluorine Bond Activation of Pentafluoropyridine at Nickel(0):  Comparative Reactivity of Fluorinated Arene and Fluorinated Pyridine Derivatives

, 2016
Reaction of hexafluorobenzene with Ni(COD)2 (COD = 1,5,-cyclooctadiene) in the presence of triethylphosphine or with Ni(PEt3)4 at room temperature results in very slow formation of trans-Ni(PEt3)2(C6F5)F (1).
Catherine L. Higgitt (3084918), Ralf Karch (2414062), Leroy Cronin (538206), Robin N. Perutz (1305213)   +3 more
core   +1 more source

Experimental Study of the Reaction of a Ni(PEt₃)₂ Synthon with Polyfluorinated Pyridines: Concerted, Phosphine-Assisted, or Radical C–F Bond Activation Mechanisms?

, 2016
The mechanisms of the C–F activation reactions of 2,3,5,6-tetrafluoropyridine and pentafluoropyridine with the phenanthrene adduct (PEt3)2Ni­(η2-C14H10) and Ni­(PEt3)4 as sources of (PEt3)2Ni were investigated.
Jillian A. Hatnean (2110288), Samuel A. Johnson (1456048)   +1 more
core   +1 more source

Selective activation of the ortho C?F bond in pentafluoropyridine by zerovalent nickel:Reaction via a metallophosphorane intermediate stabilized by neighboring group assistance from the pyridyl nitrogen

, 2010
Density functional theory is used to explore the origins of the chemoselectivity and regioselectivity of activation of C?F bonds in pentafluoropyridine with [Ni(PR3)2] species.
Perutz, Robin N., Macgregor, Stuart A., McGrady, John E., Nova, Ainara, Reinhold, Meike, Nova, A, McGrady, JE, Macgregor, SA, Reinhold, M, Perutz, RN   +9 more
core   +1 more source