Results 61 to 70 of about 448 (148)

The Application of Perfluoroheteroaromatic Reagents in the Preparation of Modified Peptide Systems [PDF]

, 2017
The perfluoroheteroaromatic reagent pentafluoropyridine has proved to be a highly reactive electrophile, undergoing SNAr arylation reactions in the presence of a range of nucleophilic peptide side chains (i.e. cysteine, tyrosine, serine and lysine) under
Dose, A, Cobb, S.L., Sandford, G, Gimenez, D, Coxon, C.R., Dose, Anica, Gimenez, Diana, Graham Sandford, Mooney, CA, Coxon, CR, Cobb, Steven L., Sandford, G., Cobb, SL, Steven L. Cobb, Sandford, Graham, Caitlin A. Mooney, Diana Gimenez, Coxon, Christopher R., Anica Dose, Mooney, Caitlin A., Mooney, C.A., Dose, A., Christopher R. Coxon, Gimenez, D.   +23 more
core   +1 more source

Synthesis of a novel tetrafluoropyridine-containing amino acid and tripeptide

, 2013
The synthesis of a novel fluoropyridine-containing amino acid from pentafluoropyridine by a nucleophilic substitution process is reported. The orthogonal protecting groups can be manipulated and the fluoropyridine amino acid incorporated into a ...
Sandford, Graham, Coxon, Christopher R., Hoose, Alex, Hudson, Alex S., Cobb, Steven L.   +4 more
core   +1 more source

Photochemical reactions of fluorinated pyridines at half-sandwich rhodium complexes: Competing pathways of reaction

, 2014
Irradiation of CpRh(PMe3)(C2H4) (1; Cp = η5-C5H5) in the presence of pentafluoropyridine in hexane solution at low temperature yields an isolable η2-C,C-coordinated pentafluoropyridine complex, CpRh(PMe3)(η2-C,C-C5NF4) (2).
Nuria Rendón (1305210), Robin J. Blagg (1305201), Procacci, Barbara, Perutz, Robin N., Rendon, Nuria, Barbara Procacci (1305207), Robin N. Perutz (1305213), Whitwood, Adrian C., Blagg, Robin J., Adrian C. Whitwood (1305204)   +9 more
core   +1 more source

Polyfunctional tetrahydropyrido[2,3-b]pyrazine scaffolds from 4-phenylsulfonyl tetrafluoropyridine

, 2005
Polyfunctional tetrahydropyrido[2,3-b]pyrazine scaffolds can be synthesized by sequential reaction of pentafluoropyridine with sodium phenylsulfinate and an appropriate diamine.
Yufit, D.S., Baron, A., Sandford, G., Slater, R., Vong, A., Howard, J.A.K.   +5 more
core   +1 more source

On pyridine chloronium cations. [PDF]

Chem Sci, 2023
Pröhm P, Berg W, Rupf SM, Müller C, Riedel S.   +4 more
europepmc   +1 more source

Polyfunctional heteroaromatic fused ring systems [PDF]

, 2005
Many current therapeutic agents are based on a core structure consisting of a fused ring heteroaromatic polycyclic system. Methodology for the synthesis of a range of these structurally diverse heteroaromatic derivatives is therefore highly desirable and
Slater, Rachel
core  

Selective Activation of the ortho C−F Bond in Pentafluoropyridine by Zerovalent Nickel: Reaction via a Metallophosphorane Intermediate Stabilized by Neighboring Group Assistance from the Pyridyl Nitrogen

, 2016
Density functional theory is used to explore the origins of the chemoselectivity and regioselectivity of activation of C−F bonds in pentafluoropyridine with [Ni(PR3)2] species.
Stuart A. Macgregor (1350846), Robin N. Perutz (1305213), Ainara Nova (1661968), Meike Reinhold (2306749), John E. McGrady (1347687)   +4 more
core   +1 more source

Au(I) Catalyzed HF Transfer: Tandem Alkyne Hydrofluorination and Perfluoroarene Functionalization. [PDF]

ACS Catal, 2022
Mulryan D, Rodwell J, Phillips NA, Crimmin MR.   +3 more
europepmc   +1 more source

Perfluoroaryl and Perfluoroheteroaryl Reagents as Emerging New Tools for Peptide Synthesis, Modification and Bioconjugation. [PDF]

Chemistry, 2022
Brittain WDG, Coxon CR.
europepmc   +1 more source

The Influence of the Halide in the Crystal Structures of 1-(2,3,5,6-Tetrafluoro-4-pyridyl)-3-benzylimidazolium Halides. [PDF]

Molecules, 2022
Acharige UAI, Saunders GC.
europepmc   +1 more source