Nanochanneled Device and Related Methods [PDF]
A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device.
Ferrari, Mauro +7 more
core +5 more sources
Mercury speciation, transformation, and transportation in soils, atmospheric flux, and implications for risk management : a critical review [PDF]
Mercury (Hg) is a potentially harmful trace element in the environment and one of the World Health Organization's foremost chemicals of concern. The threat posed by Hg contaminated soils to humans is pervasive, with an estimated 86 Gg of anthropogenic Hg
Duan, Lei +8 more
core +2 more sources
A peptide inhibiting the release of growth hormone was originally detected accidentally during studies of the distribution of growth hormone–releasing factor in the hypothalamus of rats.
Herder, W.W. (Wouter) de +3 more
core +1 more source
Structural characterization of the family GH115 alpha-glucuronidase from Amphibacillus xylanus yields insight into its coordinated action with alpha-arabinofuranosidases [PDF]
The coordinated action of carbohydrate-active enzymes has mainly been evaluated for the purpose of complete saccharification of plant biomass (lignocellulose) to sugars. By contrast, the coordinated action of accessory hemicellulases on xylan debranching
Di Leo, Rosa +10 more
core +2 more sources
Can gadolinium contrast agents be replaced with saline for direct MR arthrography of the hip? A pilot study with arthroscopic comparison. [PDF]
OBJECTIVE To compare image quality and diagnostic performance of preoperative direct hip magnetic resonance arthrography (MRA) performed with gadolinium contrast agent and saline solution.
Brunner, Alexander +7 more
core +1 more source
In vivo anticancer evaluation of the hyperthermic efficacy of anti-human epidermal growth factor receptor-targeted PEG-based nanocarrier containing magnetic nanoparticles [PDF]
Polymeric nanoparticles with targeting moieties containing magnetic nanoparticles as theranostic agents have considerable potential for the treatment of cancer. Here we report the chemical synthesis and characterization of a poly(D,L-lactide-co-glycolide)
Claudia Innocenti +11 more
core +2 more sources
Exploiting cyanine dye J-aggregates/monomer equilibrium in hydrophobic protein pockets for efficient multi-step phototherapy: An innovative concept for smart nanotheranostics [PDF]
After several decades of development in the field of near-infrared (NIR) dyes for photothermal therapy (PTT), indocyanine green (ICG) still remains the only FDA-approved NIR contrast agent. However, upon NIR light irradiation ICG can react with molecular
Alvarez Igarzabal, Cecilia Ines +7 more
core +1 more source
Combined use of UV and MS data for ICH Stability-Indication Method: Quantification and isoforms identification of intact nivolumab [PDF]
Nivolumab (Opdivo®) is a fully human immunoglobulin G4 isotype approved for the treatment of many cancers. It acts as an immune checkpoint inhibitor by blocking the interaction between PD-1 (Programmed Cell Death Protein 1) – an inhibitory receptor ...
Cabeza, José +5 more
core +1 more source
Soft Null Hypotheses: A Case Study of Image Enhancement Detection in Brain Lesions [PDF]
This work is motivated by a study of a population of multiple sclerosis (MS) patients using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to identify active brain lesions.
Crainiceanu, Ciprian M. +4 more
core +2 more sources
Antimony‐119 for radiopharmaceutical therapy: Antimony‐119 (119Sb, t1/2=38.19 h) is a promising candidate for radiopharmaceutical therapy using Auger electrons. Available literature on 119Sb is scarce, with only one successful case of chelation, and no reported in vivo applications.
Aivija Grundmane +2 more
wiley +1 more source

