Results 21 to 30 of about 5,122,965 (164)

Nanochanneled Device and Related Methods [PDF]

open access: yes, 2013
A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device.
Ferrari, Mauro   +7 more
core   +5 more sources

Mercury speciation, transformation, and transportation in soils, atmospheric flux, and implications for risk management : a critical review [PDF]

open access: yes, 2019
Mercury (Hg) is a potentially harmful trace element in the environment and one of the World Health Organization's foremost chemicals of concern. The threat posed by Hg contaminated soils to humans is pervasive, with an estimated 86 Gg of anthropogenic Hg
Duan, Lei   +8 more
core   +2 more sources

Octreotide [PDF]

open access: yes, 1996
A peptide inhibiting the release of growth hormone was originally detected accidentally during studies of the distribution of growth hormone–releasing factor in the hypothalamus of rats.
Herder, W.W. (Wouter) de   +3 more
core   +1 more source

Structural characterization of the family GH115 alpha-glucuronidase from Amphibacillus xylanus yields insight into its coordinated action with alpha-arabinofuranosidases [PDF]

open access: yes, 2021
The coordinated action of carbohydrate-active enzymes has mainly been evaluated for the purpose of complete saccharification of plant biomass (lignocellulose) to sugars. By contrast, the coordinated action of accessory hemicellulases on xylan debranching
Di Leo, Rosa   +10 more
core   +2 more sources

Can gadolinium contrast agents be replaced with saline for direct MR arthrography of the hip? A pilot study with arthroscopic comparison. [PDF]

open access: yes, 2023
OBJECTIVE To compare image quality and diagnostic performance of preoperative direct hip magnetic resonance arthrography (MRA) performed with gadolinium contrast agent and saline solution.
Brunner, Alexander   +7 more
core   +1 more source

In vivo anticancer evaluation of the hyperthermic efficacy of anti-human epidermal growth factor receptor-targeted PEG-based nanocarrier containing magnetic nanoparticles [PDF]

open access: yes, 2014
Polymeric nanoparticles with targeting moieties containing magnetic nanoparticles as theranostic agents have considerable potential for the treatment of cancer. Here we report the chemical synthesis and characterization of a poly(D,L-lactide-co-glycolide)
Claudia Innocenti   +11 more
core   +2 more sources

Exploiting cyanine dye J-aggregates/monomer equilibrium in hydrophobic protein pockets for efficient multi-step phototherapy: An innovative concept for smart nanotheranostics [PDF]

open access: yes, 2021
After several decades of development in the field of near-infrared (NIR) dyes for photothermal therapy (PTT), indocyanine green (ICG) still remains the only FDA-approved NIR contrast agent. However, upon NIR light irradiation ICG can react with molecular
Alvarez Igarzabal, Cecilia Ines   +7 more
core   +1 more source

Combined use of UV and MS data for ICH Stability-Indication Method: Quantification and isoforms identification of intact nivolumab [PDF]

open access: yes, 2022
Nivolumab (Opdivo®) is a fully human immunoglobulin G4 isotype approved for the treatment of many cancers. It acts as an immune checkpoint inhibitor by blocking the interaction between PD-1 (Programmed Cell Death Protein 1) – an inhibitory receptor ...
Cabeza, José   +5 more
core   +1 more source

Soft Null Hypotheses: A Case Study of Image Enhancement Detection in Brain Lesions [PDF]

open access: yes, 2013
This work is motivated by a study of a population of multiple sclerosis (MS) patients using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to identify active brain lesions.
Crainiceanu, Ciprian M.   +4 more
core   +2 more sources

Chemistry of Antimony in Radiopharmaceutical Development: Unlocking the Theranostic Potential of Sb Isotopes

open access: yesChemPlusChem, Volume 89, Issue 12, December 2024.
Antimony‐119 for radiopharmaceutical therapy: Antimony‐119 (119Sb, t1/2=38.19 h) is a promising candidate for radiopharmaceutical therapy using Auger electrons. Available literature on 119Sb is scarce, with only one successful case of chelation, and no reported in vivo applications.
Aivija Grundmane   +2 more
wiley   +1 more source

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