Determination of the worst case for cleaning validation of equipment used in the radiopharmaceutical production of lyophilized reagents for 99mTc labeling [PDF]
, 2016 Cleaning validation, a requirement of the current Good Manufacturing Practices (cGMP) for Drugs, consists of documented evidence that cleaning procedures are capable of removing residues to predetermined acceptance levels.
Luciana Valéria Ferrari Machado Porto +2 more
core +4 more sources
The design and preclinical evaluation of a single-label bimodal nanobody tracer for image-guided surgery [PDF]
, 2021 Intraoperative guidance using targeted fluorescent tracers can potentially provide surgeons with real-time feedback on the presence of tumor tissue in resection margins.
Bridoux, J. +10 more
core +2 more sources
Geochemistry, Geophysics, Geosystems, Volume 25, Issue 9, September 2024.Abstract Bamboo corals are promising archives of paleoceanographic conditions. Existing calibrations for element‐to‐calcium ratio (El/Ca) proxies of bamboo corals, however, are not necessarily calibrated to contemporaneous environmental parameters, thus weakening the reliability of the proxies. Here, we aim at calibrating the proxies by comparing El/Ca
Xiaoli Zhou +6 more
wiley +1 more source
Prolonged consumption of energy drinks does not affect the processes of memory, and increases the activity of transaminases, and cholesterol concentration – animal model study results [PDF]
, 2016 Background . The consumption of energy drinks (ED) is popular among young people. There are concerns that it could be harmful for their health. Objectives.
Barbara Nieradko-Iwanicka +2 more
core +1 more source
Periodontology 2000, Volume 95, Issue 1, Page 87-101, June 2024.Abstract Radiographic examination has been an essential part of the diagnostic workflow in periodontology and implant dentistry. However, radiographic examination unavoidably involves ionizing radiation and its associated risks. Clinicians and researchers have invested considerable efforts in assessing the feasibility and capability of utilizing ...
Andy Wai Kan Yeung +5 more
wiley +1 more source
The Mechanism of Low Levels of Nitrogen Dioxide Reaction With Unsaturated Fatty Acid Esters. [PDF]
, 1990 Nitrogen Dioxide is a toxic air pollutant that exists at less than 0.5 ppm in the atmosphere. This toxic compound is known to initiate autoxidation of unsaturated fatty acids both in vivo and in vitro.
Gallon, Aris Ann
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Managing antibody stability: Effects of stressors on Ipilimumab from the commercial formulation to diluted solutions [PDF]
, 2022 The stability of the monoclonal antibody Ipilimumab, the active ingredient of Yervoy®, used for the treatment of different types of cancer, has been investigated.
Benedetta Fongaro +5 more
core +2 more sources
Drug Repurposing for the Treatment of Bacterial and Fungal Infections [PDF]
, 2019 Multidrug-resistant (MDR) pathogens pose a well-recognized global health threat that demands effective solutions; the situation is deemed a global priority by the World Health Organization and the European Centre for Disease Prevention and Control ...
Andrea Miró-Canturri +2 more
core +1 more source
Conformational Stability Effect of Polymeric Iron Chelators [PDF]
, 2020 This work is licensed under a Creative Commons Attribution 4.0 International License.The design and synthesis of metal chelators with extraordinary metal affinities is a basic and challenging scientific problem of both fundamental and practical ...
Berkland, Cory, Qian, Jian
core +1 more source
Poly (L-glutamic acid)-Paclitaxel Conjugates for Cancer Treatment [PDF]
, 2012 Non
Shuang-Qing Zhang
core +2 more sources