Results 141 to 150 of about 147,283 (318)

Refractory Status Epilepticus in Children: Intention to Treat With Continuous Infusions of Midazolam and Pentobarbital*

Pediatric Critical Care Medicine, 2016
R. Tasker, H. Goodkin, Iván Sánchez Fernández, K. Chapman, N. Abend, R. Arya, J. Brenton, J. Carpenter, W. Gaillard, T. Glauser, Joshua L. Goldstein, A. Helseth, M. Jackson, K. Kapur, M. Mikati, K. Peariso, M. Wainwright, A. Wilfong, Korwyn L Williams, T. Loddenkemper   +19 more
semanticscholar   +1 more source

Osteoclast‐Derived SLIT3 Mediates Osteoarthritis Pain and Degenerative Changes

Advanced Science, EarlyView.
In TMJ‐OA, osteoclasts play a significant role in promoting the growth of sensory nerves at the osteochondral interface. In early OA, TRAP+ osteoclast‐derived SLIT3 induces sensory nerve growth into the condylar cartilage. This nerve growth facilitates the development of pain associated with OA.
Weiwei Zhu, Wenpin Qin, Jialu Gao, Yihan Guo, Xiaoxiao Han, Zhangyu Ma, Xiaokang Zhang, Jie He, Jing Liu, Bo Gao, Changjun Li, Lina Niu, Jianfei Yan, Kai Jiao   +13 more
wiley   +1 more source

Model Based Description of the Pharmacokinetic Behavior of Pentobarbital in Fasted Male Volunteers after Oral Administration of 10 mg of Pentobarbital [PDF]

, 2016
Mária Ďurišová
openalex   +1 more source

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

Advanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao, Qingzhou Kong, Haifan Gong, Lixiang Li, Jialu Fu, Boyao Wan, Peizhu Wang, Xiaojuan Li, Yue Wang, Jinghui Zhang, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +14 more
wiley   +1 more source

Influence of nephron GFR on proximal reabsorption in pentobarbital anesthetized rats

, 1974
Kenneth Steven
openalex   +1 more source

Attenuation of ischemic brain edema by pentobarbital after carotid ligation in the gerbil. [PDF]

, 1979
Pablo M. Lawner, J. Laurent, Frederick A. Simeone, Eugene A. Fink, Elliot Rubin   +4 more
openalex   +1 more source

A Biomimetic Norepinephrine‐Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical‐Sized Bone Defects

Advanced Science, EarlyView.
Inspired by the composition and structure of native bone tissue and its complex interplay of biological signals, a norepinephrine‐loaded biomimetic mineralized electrocompacted collagen scaffold (NE‐MEC) is developed capable of simultaneously supporting osteogenesis, neural repair, angiogenesis, and immune modulation.
Zhengyun Ren, Zhaojun Wu, Anhang Wu, Hui Zhang, Jiachen Lu, Jiahao Zhang, Jie Weng, Jinhua Zhang, Song Chen, Huan Tan, Tailin Guo   +10 more
wiley   +1 more source

A Comparison of the Effects of Hypothermia, Pentobarbital, and Isoflurane on Cerebral Energy Stores at the Time of Ischemic Depolarization  [PDF]

, 1995
Marleen Verhaegen, Paul A. Iaizzo, Michael M. Todd   +2 more
openalex   +1 more source

Quantification of sodium pentobarbital residues from equine mortality compost piles.

Journal of Animal Science, 2015
Josh Payne, Rodney Farris, Gene Parker, Jean Bonhotal, M. Schwarz   +4 more
semanticscholar   +1 more source

Macrophage–Derived Ferritin Exacerbates Silica‐Induced Pulmonary Fibrosis via PIK3R2‐Mediated Fibroblast Differentiation

Advanced Science, EarlyView.
This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Liqun Wang, Xuxi Chen, Hongying Quan, Rui Qian, Shuyu Gong, Qiurong He, Ying Gao, Ajia Axi, Manyu Zhao, Qin Zhang, Ling Zhang, Lijun Peng, Xin Sun, Ben Zhang, Yuqin Yao   +14 more
wiley   +1 more source