Results 151 to 160 of about 52,401 (289)

Effects of Anesthesia with Pentobarbital/Ketamine on Mitochondrial Permeability Transition Pore Opening and Ischemic Brain Damage

Biomedicines
Background and Objective: The alteration of mitochondrial functions, especially the opening of the mitochondrial permeability transition pore (mPTP), has been proposed as a key mechanism in the development of lesions in cerebral ischemia, wherefore it is
Evelina Rekuviene, Laima Ivanoviene, Vilmante Borutaite, Ramune Morkuniene   +3 more
doaj   +1 more source

Amniotic-Fluid Ingestion Enhances the Central\ud Analgesic Effect of Morphine [PDF]

, 1991
Amniotic fluid and placenta contain a substance (POEF) that when ingested enhances opioid-mediated analgesia produced by several agents (morphine injection, vaginal/cervical stimulation, late pregnancy, footshock), but not that produced by aspirin ...
DiPirro, Jean M., Kristal, Dr. Mark B., Thompson, Alexis C.   +2 more
core  

Targeted Delivery of α‐ketoglutarate to Macrophages in Bone: A Novel Therapeutic Strategy for Improving Fracture Healing in Type 2 Diabetes

Advanced Science, EarlyView.
The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang, Jiahao Cao, Siqi Zhang, Hongli Chen, Xuebing Yu, Xinli Wang, Tianji Wang, Wei Cao, Wengang Dong, Xinsen Lin, Jia Li, Wei Lei, Yafei Feng   +12 more
wiley   +1 more source

INTERACTION BETWEEN PENTOBARBITAL AND DECREASED CALCIUM ION ON GUINEA PIG ATRIA

, 1966
TY N. SMITH, ALDO N. CORBASCIO
openalex   +2 more sources

Acid‐Triggered Dual‐Functional Hydrogel Platform for Enhanced Bone Regeneration

Advanced Science, Volume 12, Issue 11, March 20, 2025.
In this study, HG‐AA1:1‐SDF‐1α composite hydrogel can respond to the acidic microenvironment to continuously release SDF‐1α, which recruited endogenous mesenchymal stem cells (MSCs) and immediately metabolize Arg‐CDs into the bioactive nitric oxide (NO) in the presence of Ca2+, activating NO/cyclic guanosine monophosphate (cGMP) signaling pathway to ...
Yao Xiao, Jinjin Ma, Xiaonan Yuan, Huan Wang, Fengyu Ma, Jun Wu, Qianglong Chen, Jie Hu, Lijie Wang, Zhendong Zhang, Chao Wang, Jiaying Li, Weishan Wang, Bin Li   +13 more
wiley   +1 more source

Potentiation of Pentobarbital Anesthesia by Competitive Protein Binding [PDF]

, 1963
Elliott C. Lasser, Gonzalo Elizondo-Martel, Richard C. Granke   +2 more
openalex   +1 more source

An Off‐the‐Shelf Artificial Proregenerative Macrophage for Pressure Ulcer Treatment

Advanced Science, EarlyView.
Artificial macrophages (artM) by encapsulating M2 lysates into biodegradable PLGA microspheres and coated with macrophage membrane, are engineered as new therapeutics against skin pressure ulcer. In mouse models, the artM exhibited robust tissue repair through cell recruitment and microenvironment modulation, showing great therapeutic potential for ...
Qi Su, Jingrong Wang, Yini Huangfu, Rui Gao, Pengxu Kong, Yu Gao, Huijuan Song, Ju Zhang, Pingsheng Huang, Chuangnian Zhang, Zujian Feng, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Sodium Pentobarbital and Scopolamin Analgesia in Labor*

, 1934
ALICE MCNEAL, Carl Philip Bauer, Hayworth Sanford   +2 more
openalex   +1 more source

Trifunctional Sialylation‐Based SF‐ZIF@NA Hydrogel for Selective Osteoclast Inhibition and Enhanced Bone‐Vessel Regeneration in Osteoporotic Bone Defects

Advanced Science, EarlyView.
This study introduces the SF‐ZIF@NA hydrogel system for osteoporotic bone defect treatment. The hydrogel inhibits osteoclast fusion by removing sialic acid and preserves the anabolic function of precursor osteoclasts (pOCs). It also releases Zn2⁺ in acidic conditions, promoting osteogenesis and angiogenesis.
Zhengrong Chen, Wenxin Yang, Yong Tang, Qianqian Dong, Kui Huang, Jiulin Tan, Jie Zhang, Juan Cai, Qixiu Yu, Qijie Dai, Jianzhong Xu, Shuquan Guo, Ce Dou, Fei Luo   +13 more
wiley   +1 more source

Influences of Tridione on Actions of Central stimulants in Pentobarbital-anesthetized Mice

, 1959
Rieko Ikeda
openalex   +2 more sources