Results 11 to 20 of about 52,516 (291)
Unexpected epileptogenic effect of lethal doses of pentobarbital: a case report [PDF]
Background Barbiturate poisoning is rare but potentially fatal. Case Report We reported a case of barbiturate poisoning in a 28-year-old woman who recovered from lethal pentobarbital deliberate self-poisoning.
Amélie Giudicelli-Bailly+5 more
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Refinement is one of the principles aiming to promote welfare in research animals. The techniques used during an experimental protocol, including euthanasia selection, must prevent and minimize suffering.
Adriana Domínguez-Oliva+5 more
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Status epilepticus (SE) is a medical emergency associated with acute severe systemic damage and high mortality. Moreover, symptomatic SE is one of the highest risk factors for epileptogenesis.
Xiangzhen Tong+9 more
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Defining a “Good Death”: Exploring Veterinarians’ Perceptions of Companion Animal Euthanasia
This study was designed to determine how veterinarians define a good euthanasia experience. This information is used to generate a working definition of companion animal euthanasia that aligns with animal welfare standards and pet owners’ expectations ...
Lori R. Kogan, Kathleen A. Cooney
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Tanacetum parthenium enhances pentobarbital-induced sleeping behaviors [PDF]
Objective: Sleep disorders are among the most common psychiatric and medical conditions. In the present study, the hypnotic effect of Tanacetum parthenium was studied in mice. Material and Methods: The hydro-alcoholic extract (HAE) of T.
Fatemeh Forouzanfar+7 more
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Pentobarbital is a drug of choice to limit motion in children during paediatric procedural sedations (PPSs). However, despite the rectal route being preferred for infants and children, no pentobarbital suppositories are marketed, and therefore they must ...
Matthieu Lebrat+10 more
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Comparison of the effects of propofol and pentobarbital on hydrogen peroxide-stimulated hepatic SNU761 cells [PDF]
BackgroundPropofol and barbiturates are both known to protect cells of several organs against ischemia/reperfusion injury, but there are few reports on any possible protective effects on human hepatocytes. We investigated the activities of both agents on
Ji Yeon Lee+5 more
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Correction for Inhibition Leads to an Allosteric Co-Agonist Model for Pentobarbital Modulation and Activation of α1β3γ2L GABAA Receptors. [PDF]
BACKGROUND:Pentobarbital, like propofol and etomidate, produces important general anesthetic effects through GABAA receptors. Photolabeling also indicates that pentobarbital binds to some of the same sites where propofol and etomidate act.
Alexis M Ziemba, Stuart A Forman
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Case report: Fatal poisoning caused by additive effects of two barbiturates
A case of fatal poisoning involving multiple psychotropic drugs is presented. Quantitative toxicological analysis showed femoral blood concentrations of pentobarbital, phenobarbital, duloxetine, acetaminophen and tramadol were 10.39, 22.57, 0.22, 0.61 ...
Sella Takei+9 more
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Pentobarbital Anesthesia Suppresses the Glucose Response to Acute Intermittent Hypoxia in Rat
A key feature of sleep disordered breathing syndromes, such as obstructive sleep apnea is intermittent hypoxia. Intermittent hypoxia is well accepted to drive the sympathoexcitation that is frequently associated with hypertension and diabetes, with ...
Polina E. Nedoboy+5 more
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