Results 11 to 20 of about 147,283 (318)

Unexpected epileptogenic effect of lethal doses of pentobarbital: a case report [PDF]

Journal of Neurocritical Care, 2023
Background Barbiturate poisoning is rare but potentially fatal. Case Report We reported a case of barbiturate poisoning in a 28-year-old woman who recovered from lethal pentobarbital deliberate self-poisoning.
Amélie Giudicelli-Bailly, Chiara Della Badia, Marc Augsburger, Hervé Quintard, Raphaël Giraud, Pia De Stefano   +5 more
doaj   +1 more source

Thermal Response of Laboratory Rats (Rattus norvegicus) during the Application of Six Methods of Euthanasia Assessed by Infrared Thermography

Animals, 2023
Refinement is one of the principles aiming to promote welfare in research animals. The techniques used during an experimental protocol, including euthanasia selection, must prevent and minimize suffering.
Adriana Domínguez-Oliva, Ismael Hernández-Ávalos, Adriana Olmos-Hernández, Juan Villegas-Juache, Antonio Verduzco-Mendoza, Daniel Mota-Rojas   +5 more
doaj   +1 more source

A literature review on current practices, knowledge, and viewpoints on pentobarbital euthanasia performed by veterinarians and animal remains disposal in the United States.

Journal of the American Veterinary Medical Association, 2023
Sodium pentobarbital and pentobarbital combination products are commonly used by veterinarians throughout the US for euthanasia of their animal patients.
Nathaniel S Kollias, Warren J Hess, Cia L. Johnson, M. Murphy, G. Golab   +4 more
semanticscholar   +1 more source

Comparisons of α2-Adrenergic Agents, Medetomidine and Xylazine, with Pentobarbital for Anesthesia: Important Pitfalls in Diabetic and Nondiabetic Rats

Journal of Ocular Pharmacology and Therapeutics, 2021
Purpose: Anesthesia is necessary to conduct rodent electroretinograms (ERGs). We evaluated utility of the α2-agonist medetomidine versus xylazine for ERG studies in nondiabetic and diabetic rats. Pentobarbital was included as a comparator.
A. Connell, Michelle B. Hookham, Dongxu Fu, D. Brazil, T. Lyons, Jeremy Y Yu   +5 more
semanticscholar   +1 more source

Development and Stability of a New Formulation of Pentobarbital Suppositories for Paediatric Procedural Sedation

Pharmaceutics, 2023
Pentobarbital is a drug of choice to limit motion in children during paediatric procedural sedations (PPSs). However, despite the rectal route being preferred for infants and children, no pentobarbital suppositories are marketed, and therefore they must ...
Matthieu Lebrat, Yassine Bouattour, Coralie Gaudet, Mouloud Yessaad, Mireille Jouannet, Mathieu Wasiak, Imen Dhifallah, Eric Beyssac, Ghislain Garrait, Philip Chennell, Valérie Sautou   +10 more
doaj   +1 more source

A Comparison of Epileptogenic Effect of Status Epilepticus Treated With Diazepam, Midazolam, and Pentobarbital in the Mouse Pilocarpine Model of Epilepsy

Frontiers in Neurology, 2022
Status epilepticus (SE) is a medical emergency associated with acute severe systemic damage and high mortality. Moreover, symptomatic SE is one of the highest risk factors for epileptogenesis.
Xiangzhen Tong, Zizhu Zhang, Jianping Zhu, Shuji Li, Shaogang Qu, Bing Qin, Yanwu Guo, Rongqing Chen, Rongqing Chen, Rongqing Chen   +9 more
doaj   +1 more source

Tanacetum parthenium enhances pentobarbital-induced sleeping behaviors [PDF]

Avicenna Journal of Phytomedicine, 2019
Objective: Sleep disorders are among the most common psychiatric and medical conditions. In the present study, the hypnotic effect of Tanacetum parthenium was studied in mice.  Material and Methods: The hydro-alcoholic extract (HAE) of T.
Fatemeh Forouzanfar, Hamed Ghazavi, Mohammad Mahdi Vahedi, Kimia Tarah, Zahra Yavari, Azar Hosseini, Azita Aghaee, Hasan Rakhshandeh   +7 more
doaj   +1 more source

Defining a “Good Death”: Exploring Veterinarians’ Perceptions of Companion Animal Euthanasia

Animals, 2023
This study was designed to determine how veterinarians define a good euthanasia experience. This information is used to generate a working definition of companion animal euthanasia that aligns with animal welfare standards and pet owners’ expectations ...
Lori R. Kogan, Kathleen A. Cooney
doaj   +1 more source

Review of Intraperitoneal Injection of Sodium Pentobarbital as a Method of Euthanasia in Laboratory Rodents.

Journal of the American Association for Laboratory Animal Science, 2020
Euthanasia is one of the most commonly performed procedures in biomedical research, involving tens of millions of animals in North America and Europe every year.
Colin A Laferriere, D. Pang
semanticscholar   +1 more source

Comparison of the effects of propofol and pentobarbital on hydrogen peroxide-stimulated hepatic SNU761 cells [PDF]

Korean Journal of Anesthesiology, 2010
BackgroundPropofol and barbiturates are both known to protect cells of several organs against ischemia/reperfusion injury, but there are few reports on any possible protective effects on human hepatocytes. We investigated the activities of both agents on
Ji Yeon Lee, Jin-Woo Shin, Eun Ho Lee, Seung-Hye Baek, Seung Woo Ku, Joung Uk Kim   +5 more
doaj   +1 more source