Results 201 to 210 of about 173,723 (335)

Local Cerebral Glucose Utilization during Nitrous Oxide and Pentobarbital Anesthesia in Rats [PDF]

open access: bronze, 1985
Takefumi Sakabe   +4 more
openalex   +1 more source

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

open access: yesAdvanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song   +17 more
wiley   +1 more source

Inhibition of Macrophage ARID3A Alleviates Myocardial Ischemia‐Reperfusion Injury After Heart Transplantation by Reducing THBS1/CD47 Signaling‐Mediated Neutrophil Extracellular Traps Formation

open access: yesAdvanced Science, EarlyView.
This study reveals that ARID3A in macrophages can transcriptionally regulate the THBS1‐CD47 axis after heart transplantation (HT), thereby inducing activated neutrophils to release NETs through the p38 MAPK signaling pathway. The itaconate derivative 4‐OI can inhibit ARID3A in macrophages and promote the accumulation of antioxidant factors, thereby ...
Hao Tian   +7 more
wiley   +1 more source

Hippocampal Transcriptome Analysis in a Mouse Model of Chronic Unpredictable Stress Insomnia. [PDF]

open access: yesBiomedicines
Zhang S   +8 more
europepmc   +1 more source

Virulence‐Selective Trap–Capture–Kill Antibacterial Nanostructures With Immune–Metabolic Regulation for Treating Implant‐Associated Infections

open access: yesAdvanced Science, EarlyView.
A virulence‐selective antibacterial system based on fascaplysin derivative 14‐modified TiO2 nanostructure (F‐14‐TNA) is developed for treating implant‐associated infections. F‐14‐TNA selectively traps hyperpathogenic bacteria via chemotaxis, captures them electrostatically, and kills them via reactive oxygen species‐mediated pathways.
Xiaodong Hu   +9 more
wiley   +1 more source

A Multifunctional Molecular Probe for Multimodal Imaging‐Guided Potent Photothermal/Photodynamic Therapy of Endometriosis

open access: yesAdvanced Science, EarlyView.
The cRGD‐ILD molecular probe integrates clinically available components: a cRGD peptide (integrin αvβ3 targeting), ICG (for fluorescence/photoacoustic imaging and phototherapy), and Gd‐DTPA (MRI contrast). Utilizing small size and receptor targeting, it achieves selective lesion accumulation.
Qiyu Zhong   +9 more
wiley   +1 more source

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