Results 261 to 270 of about 178,601 (316)

Attenuation of arsenic trioxide‐induced endothelial injury: unveiling the protective role of ginkgolic acid through inhibition of TRPM4 SUMOylation: Evidence from Raman cellular imaging

open access: yesVIEW, EarlyView.
Inhibiting the SUMOylation modification of TRPM4 can prevent the vascular endothelial damage caused by ATO. Inhibition of TRPM4 SUMOylation, either pharmacologically by GA or genetically by the K618R mutation, protects against ATO‐induced vascular endothelial damage.
Ting‐Ting Tong   +18 more
wiley   +1 more source

Multifunctional antimicrobial peptide‐containing electrospun nanofibrous dressings for accelerating wound healing with exposed bone

open access: yesVIEW, EarlyView.
(a) Schematic representation of the chemical cross‐linking of PVB/PCL‐TiO2‐RegIIIγ electrospun nanofibers. (b) Schematic illustration of the biomimetic dressing promoting healing in an exposed bone wound. The treatment of wounds with exposed bone has always been a difficult problem in the clinical treatment of orthopedics.
Chenhao Gong   +6 more
wiley   +1 more source

Study on the Vocal Fold Movement Characteristics of Canine Models With Nerve Paralysis Caused by Different Site Injuries

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To explore the specific effects of unilateral injuries to the vagus nerve (VN), recurrent laryngeal nerve (RLN), and superior laryngeal nerve (SLN) on the vocal fold movement characteristics, and investigate the regulation pattern of current intensity on the vocal fold movement after the injuries.
Meng‐Xuan Shi   +2 more
wiley   +1 more source

Sex‐Specific Involvement of Gut Microbiota in Behavioral and Endocrine Responses to Chronic Predator Odor in Brandt's Voles

open access: yesIntegrative Zoology, EarlyView.
18 days of predator odor exposure altered gut microbiota, increased anxiety‐like behaviors, and elevated hypothalamic–pituitary–adrenal axis activity in Brandt's voles, with males showing behavioral habituation and females remaining sensitive. Cecal microbiota transplantation experiments confirmed that only female recipients of microbiota from predator‐
Chen Gu   +6 more
wiley   +1 more source

Role for Complement C5 in Eosinophilic Inflammation of Severe Asthma

open access: yesAllergy, EarlyView.
Complement activation module, particularly C5, is positively associated with eosinophilic inflammation in severe asthma cohorts. Elevated C5 expression correlates with poor lung function improvement and persistent eosinophilic inflammation. Mouse model studies confirm that C5 exacerbates eosinophilic inflammation, highlighting its potential as a ...
Cong Dong   +217 more
wiley   +1 more source

The antagonism of platelet-activating factor and hyperacute organ rejection [PDF]

open access: yes, 1990
Banner, B   +12 more
core  

Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

open access: yesAllergy, EarlyView.
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng   +20 more
wiley   +1 more source

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