Results 41 to 50 of about 147,283 (318)

The Study of Improvement in Sleep Function with Compounded Formulations of Ziziphus jujuba Extract, Longan Lour Extract, γ-Amino Butyric Acid, and Casein Hydrolysate

Shipin gongye ke-ji, 2023
In this paper, through the direct sleep experiment, the experiment of prolonging the sleep time of pentobarbital sodium, the hypnosis experiment of subthreshold dose of pentobarbital sodium and the sleep latency experiment of pentobarbital sodium, the ...
Yujing YAO, Shumin ZHANG, Yanyan REN, Zhao YANG, Jiajia HUANG   +4 more
doaj   +1 more source

Genes ingenuity pathway analysis unveils smoothelin‐like 1 (SMTNL1) as a key regulatory protein involved in sodium pentobarbital‐induced growth inhibition in breast cancer

Pharmacology Research & Perspectives, 2023
We previously reported that sodium pentobarbital inhibited the growth of the breast cancer associated with the normalization of microcirculatory hemodynamics and oxygenation.
Bingwei Li, Xiaoyan Zhang, Xueting Liu, Ailing Li, Jianqun Han   +4 more
doaj   +1 more source

Effects of pentobarbital, isoflurane, or medetomidine-midazolam-butorphanol anesthesia on bronchoalveolar lavage fluid and blood chemistry in rats.

Journal of Toxicological Sciences, 2016
Bronchoalveolar lavage fluid (BALF) is commonly examined for pulmonary toxicity in animal studies. Two common means of anesthesia before euthanasia and bronchoalveolar lavage in rats are intraperitoneal injection of pentobarbital and inhalation of ...
Y. Tsubokura, Toshio Kobayashi, Y. Oshima, N. Hashizume, M. Nakai, Shozo Ajimi, N. Imatanaka   +6 more
semanticscholar   +1 more source

Renal function and histology after acute hemorrhage in rats under dexmedetomidine action Função e histologia renais após hemorragia aguda em ratos sob ação da dexmedetomidina

Acta Cirúrgica Brasileira, 2007
PURPOSE: About 50 % of indications for dialysis in acute renal failure are related to problems originated during the perioperative period. Intraoperative hemodynamic changes lead to renal vasoconstriction and hypoperfusion.
Marco Aurelio Marangoni, Alex Hausch, Pedro Thadeu Galvão Vianna, José Reinaldo Cerqueira Braz, Rosa Marlene Viero, Yara Marcondes Machado Castiglia   +5 more
doaj   +1 more source

Is pentobarbital safe and efficacious in the treatment of super-refractory status epilepticus: a cohort study

Critical Care, 2014
IntroductionSeizures refractory to third-line therapy are also labeled super-refractory status epilepticus (SRSE). These seizures are extremely difficult to control and associated with poor outcome.
D. Pugin, B. Foreman, Gian Marco De Marchis, A. Fernández, J. M. Schmidt, B. Czeisler, S. Mayer, S. Agarwal, C. Lesch, Hector Lantigua, J. Claassen   +10 more
semanticscholar   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Changes in breathing pattern during severe hypothermia and autoresuscitation from hypothermic respiratory arrest in anesthetized mice

Physiological Reports, 2021
Some evidence suggests that both hypothermia and anesthesia can exert similar effects on metabolism and ventilation. This study examined the synergistic effects of anesthesia and hypothermia on ventilation in spontaneously breathing adult mice under ...
Saki Taiji, Takashi Nishino, Hisayo Jin, Norihiro Shinozuka, Natsuko Nozaki‐Taguchi, Shiroh Isono   +5 more
doaj   +1 more source

Pachymic Acid Enhances Pentobarbital-Induced Sleeping Behaviors via GABAA-ergic Systems in Mice

Biomolecules & Therapeutics, 2014
This study was investigated to know whether pachymic acid (PA), one of the predominant triterpenoids in Poria cocos (Hoelen) has the sedative-hypnotic effects, and underlying mechanisms are mediated via γ-aminobutyric acid (GABA)-ergic systems.
V. K. Shah, Jae Joon Choi, Jin-Yi Han, M. Lee, J. Hong, K. Oh   +5 more
semanticscholar   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Assessment of Carbon Dioxide, Carbon Dioxide/Oxygen, Isoflurane and Pentobarbital Killing Methods in Adult Female Sprague-Dawley Rats. [PDF]

PLoS ONE, 2016
Exposure to carbon dioxide (CO2) gas as a killing method is aversive and exposure to high concentrations is likely to be painful. Bradycardia during exposure to CO2 is associated with nociception and pain.
Jessica M Chisholm, Daniel S J Pang
doaj   +1 more source