Results 51 to 60 of about 165,661 (337)

Autonomic Nervous System under Ketamine/xylazine and Pentobarbital Anaesthesia in a Wistar Rat Model: A Chronobiological View

open access: yesPrague Medical Report, 2013
The aim of the present study was to determine the effect of ketamine/xylazine and pentobarbital anaesthesia on heart rate variability as a marker of autonomic nervous system activity. The experiments were performed in ketamine/xylazine (10 mg/kg/15 mg/kg)
Pavol Švorc, Jr.   +3 more
doaj   +1 more source

Assessment of Carbon Dioxide, Carbon Dioxide/Oxygen, Isoflurane and Pentobarbital Killing Methods in Adult Female Sprague-Dawley Rats. [PDF]

open access: yesPLoS ONE, 2016
Exposure to carbon dioxide (CO2) gas as a killing method is aversive and exposure to high concentrations is likely to be painful. Bradycardia during exposure to CO2 is associated with nociception and pain.
Jessica M Chisholm, Daniel S J Pang
doaj   +1 more source

Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration

open access: yesAdvanced Functional Materials, EarlyView.
A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo   +10 more
wiley   +1 more source

Spectroscopic Investigations of Pentobarbital Interaction with Transthyretin

open access: yesJournal of Spectroscopy, 2013
Transthyretin (TTR) aggregation has been characterized to be responsible for several amyloid diseases. Fourier transform infrared (FTIR) spectroscopy, fluorescence, and atomic force microscopy (AFM) are used to investigate secondary structure changes in ...
Saqer M. Darwish   +4 more
doaj   +1 more source

Spike timing rigidity is maintained in bursting neurons under pentobarbital-induced anesthetic conditions

open access: yesFrontiers in Neural Circuits, 2016
Pentobarbital potentiates γ-aminobutyric acid (GABA)-mediated inhibitory synaptic transmission by prolonging the open time of GABAA receptors. However, it is unknown how pentobarbital regulates cortical neuronal activities via local circuits in vivo.
Risako Kato   +4 more
doaj   +1 more source

Lycium‐Barbarum Polysaccharide‐Loaded Dual‐Crosslinked Rigid Hydrogel Enhances Bone Healing in Diabetic Bone Defects by Scavenging Reactive Oxygen Species

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel hydrogel (HLBP) incorporating natural polysaccharides from goji berries is developed to enhance diabetic bone defect healing. The hydrogel efficiently scavenges ROS, improves osteogenic differentiation, and promotes in vivo bone regeneration. This strategy offers a biocompatible and localized approach, overcoming the challenges of traditional ...
Wenjie Zhong   +9 more
wiley   +1 more source

Effects of anesthetics on the renal sympathetic response to anaphylactic hypotension in rats. [PDF]

open access: yesPLoS ONE, 2014
The autonomic nervous system plays an important role in rat anaphylactic hypotension. It is well known that sympathetic nerve activity and cardiovascular function are affected by anesthetics.
Lingling Sun   +5 more
doaj   +1 more source

Antinociceptive activity of Thyme (Thymus vulgaris L.) and interactions with neurotropics and analgesics

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2021
The plant world represents an important source of potential therapeutic agents, but concomitant administration of herbal and conventional medications may result in interactions with subsequent beneficial or adverse effects.
Aleksandar Lazar Rašković   +7 more
doaj   +1 more source

Cardiac Organoid Model Inspired Micro‐Robot Smart Patch to Treat Myocardial Infarction

open access: yesAdvanced Materials, EarlyView.
The heart organoid model exhibits the acidic microenvironment characteristic of myocardial infarction, which emerges as a pivotal force propelling the movement of micro‐robots. These micro‐robots, administered through microneedles, can penetrate deep into the tissue, effectively delivering therapeutic payloads to facilitate heart repair.
Fangfang Wang   +12 more
wiley   +1 more source

Pentobarbital-Induced Myocardial Stunning in Status Epilepticus Requiring Extracorporeal Membrane Oxygenation: A Case Report and Literature Review

open access: yesCase Reports in Critical Care, 2016
Introduction. Mild hypotension is a well-recognized complication of intravenous pentobarbital; however fulminant cardiopulmonary failure has not been previously reported. Case Report.
Tapan Kavi   +4 more
doaj   +1 more source

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