Results 61 to 70 of about 178,601 (316)

Astrocyte‐Guided Maturation of Neural Constructs in a Modular Biosynthetic Hydrogel for Biohybrid Neurotechnologies

open access: yesAdvanced Functional Materials, EarlyView.
A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta   +4 more
wiley   +1 more source

Spike timing rigidity is maintained in bursting neurons under pentobarbital-induced anesthetic conditions

open access: yesFrontiers in Neural Circuits, 2016
Pentobarbital potentiates γ-aminobutyric acid (GABA)-mediated inhibitory synaptic transmission by prolonging the open time of GABAA receptors. However, it is unknown how pentobarbital regulates cortical neuronal activities via local circuits in vivo.
Risako Kato   +4 more
doaj   +1 more source

Effects of anesthetics on the renal sympathetic response to anaphylactic hypotension in rats. [PDF]

open access: yesPLoS ONE, 2014
The autonomic nervous system plays an important role in rat anaphylactic hypotension. It is well known that sympathetic nerve activity and cardiovascular function are affected by anesthetics.
Lingling Sun   +5 more
doaj   +1 more source

In vitro identification and in silico utilization of interspecies sequence similarities using GeneChip(® )technology [PDF]

open access: yes, 2005
BACKGROUND: Genomic approaches in large animal models (canine, ovine etc) are challenging due to insufficient genomic information for these species and the lack of availability of corresponding microarray platforms. To address this problem, we speculated
Garcia, Joe GN   +5 more
core   +3 more sources

Gold Nanoclusters as Dual Agents for Engineering Tumor Vascular Leakiness and Performing Photothermal Therapy

open access: yesAdvanced Functional Materials, EarlyView.
Many cancer nanotherapeutics, while potent, suffer from the inability to escape from the tumor vasculature, especially in the absence of endothelial permeability. In this work, ultrasmall gold nanoclusters could engineer nanomaterials induced endothelial leakiness (NanoEL) and harness strong NIR induced photothermal characteristics to suppress tumor ...
Nengyi Ni   +8 more
wiley   +1 more source

The Daily Texan [PDF]

open access: yes, 2013
Texas Student ...
University of Texas at Austin
core  

An Innovative “Tooth‐On‐Chip” Microfluidic Device Emulating the Structure and Physiology of the Dental Pulp Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
This work presents a “tooth‐on‐chip” device that mimics dental pulp tissue. By co‐culturing key cell types, it recreates vascular networks, stem cell niches, the odontoblast/dentine interface, and trigeminal innervation. This innovative platform provides a unique model of dental pulp structure and physiology, with significant potential for accelerating
Alessandro Cordiale   +6 more
wiley   +1 more source

Pentobarbital-Induced Myocardial Stunning in Status Epilepticus Requiring Extracorporeal Membrane Oxygenation: A Case Report and Literature Review

open access: yesCase Reports in Critical Care, 2016
Introduction. Mild hypotension is a well-recognized complication of intravenous pentobarbital; however fulminant cardiopulmonary failure has not been previously reported. Case Report.
Tapan Kavi   +4 more
doaj   +1 more source

Effects of Propofol on Electrocardiogram Measures in Mice

open access: yesJournal of Pharmacological Sciences, 2014
.: We investigated the anesthetic effects of propofol on the electrocardiogram (ECG) in mice. We also compared the effects of isoflurane (2%) inhalation anesthesia, intraperitoneal propofol (50 or 100 mg/kg), and pentobarbital (50 mg/kg) on ECG in mice ...
Tomohiro Shintaku   +10 more
doaj   +1 more source

Effects of Methotrexate on IL-6alphar, VCAM-1 and NF Kappa B Expression in a Rat Model of Metabolic Syndrome [PDF]

open access: yes, 2016
Background: In this study, we used Methotrexate (Mtx) to examine the role of immunomodulation on the activation of IL-6 and VCAM-1, which could generate a microenvironment that supports cardiovascular remodelling.Methods: Male WKY and SHR rats were ...
Diez, Emiliano Raúl   +4 more
core   +1 more source

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