Results 61 to 70 of about 165,661 (337)
Assessment of molecular action of direct gating and allosteric modulatory effects of meprobamate (MiltownRTM) on GABA A receptors [PDF]
, 2016 Meprobamate (tradenames Miltown, Equanil) is a schedule IV anxiolytic and the primary metabolite of the muscle relaxant carisoprodol. Meprobamate modulates GABAA (gamma-aminobutyric acid type A) receptors, and has been described as having barbiturate ...
Kumar, Manish
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Assessment of Neuropharmacological Profile of Ethanolic Extract of Lawsonia Inermis Flowers [PDF]
, 2020 On preliminary basis neuropharmacological profile of ethanolic extract of flowers of Lawsonia inermis was carried out. For assessing the activity of flowers on central nervous system locomotor activity using actophotometer, muscle relaxant activity using
G, Hemalatha +3 more
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Flexible 3D Kirigami Probes for In Vitro and In Vivo Neural Applications
Advanced Materials, EarlyView.A customizable and scalable approach to fabricate flexible 3D kirigami microelectrode arrays (MEAs) featuring up to 128 shanks, including surface and penetrating electrodes designed to interact with the 3D space of neural tissue, is presented. The 3D kirigami MEAs are successfully deployed in several neural applications, both in vitro and in vivo, and ...
Marie Jung +10 more
wiley +1 more source
Upconversion‐Based Remote Deep Brain Modulation for Therapeutic Dissection of Parkinson's Disease
Advanced Therapeutics, EarlyView.An upconversion‐based wireless optogenetic strategy enables an all‐optical deep brain modulation solution for treating Parkinson's disease in rodent animals without using electronics or any tethered cables, providing experimental evidence supporting a therapeutic mechanism of STN‐DBS by disruption of anterograde signal transmission along the indirect ...
Wenchong Zhang +13 more
wiley +1 more source
Advanced Science, EarlyView.This study elucidates the crosstalk between tumor‐associated macrophages (TAMs) and anaplastic thyroid cancer stem cells (ATCSCs). The findings reveal that CCL20 from THP‐1‐M2 activates the IRAK‐1/NF‐κB1/2 pathway in ATCSCs, thereby enhancing CXCL5 secretion.
Qi Liu +11 more
wiley +1 more source
Disruption of Hippocampal Multisynaptic Networks by General Anesthetics. [PDF]
, 2017 BACKGROUND: Previous studies showed that synaptic transmission is affected by general anesthetics, but an anesthetic dose response in freely moving animals has not been done.
Kuo, Min-Ching, Leung, L Stan
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Advanced Science, EarlyView.Lycium barbarum glycopeptide (LBGP), which is further extracted from Lycium barbarum polysaccharides, exhibits significant protective effects against neomycin‐induced hearing dysfunction including oxidative stress in cochlea and loss of key cells in cochlea.
Yunhao Wu +12 more
wiley +1 more source
Stability-Indicating Assay for the Determination of Pentobarbital Sodium in Liquid Formulations
International Journal of Analytical Chemistry, 2015 A stability-indicating assay by reversed-phase high performance liquid chromatography (RP-HPLC) method was developed for the determination of pentobarbital sodium in oral formulations: a drug used for infant sedation in computed tomography (CT) or ...
Myriam Ajemni +6 more
doaj +1 more source
Advanced Science, EarlyView.Selective lesioning of SuM glutamatergic neurons promoted the induction of and delayed emergence from sevoflurane anesthesia and increased sevoflurane sensitivity. Optogenetic stimulation of SuM glutamatergic neurons or the SuM‐MS projection promoted behavioral arousal and cortical activation under steady‐state sevoflurane anesthesia and reduced the ...
Jiayan Li +8 more
wiley +1 more source
Spectroscopic investigations of pentobarbital interaction with human serum albumin [PDF]
, 2010 The interaction between pentobarbital and human serum albumin has been investigated. The basic binding interaction was studied by UV-absorption and fluorescence spectroscopy.
Abu sharkh, Sawsan E. +4 more
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