Results 1 to 10 of about 371 (121)

Insights into the autotrophic CO2 fixation pathway of the archaeon Ignicoccus hospitalis: comprehensive analysis of the central carbon metabolism. [PDF]

J Bacteriol, 2007
Ignicoccus hospitalis is an autotrophic hyperthermophilic archaeon that serves as a host for another parasitic/symbiotic archaeon, Nanoarchaeum equitans. In this study, the biosynthetic pathways of I.
Jahn U, Huber H, Eisenreich W, Hügler M, Fuchs G.   +4 more
europepmc   +2 more sources

Histone H4 lysine 16 acetylation controls central carbon metabolism and diet-induced obesity in mice [PDF]

, 2021
Noncommunicable diseases (NCDs) account for over 70% of deaths world-wide. Previous work has linked NCDs such as type 2 diabetes (T2D) to disruption of chromatin regulators. However, the exact molecular origins of these chronic conditions remain elusive.
Akhtar, A., Chatterjee, A., Pessoa Rodrigues, C., Shvedunova, M., Stehle, T., Szymanski, W., Wiese, M.   +6 more
core   +2 more sources

Differential sensitivity of metabolic pathways in sugar beet roots to combined salt, heat, and light stress

Physiologia Plantarum, Volume 174, Issue 5, September/October 2022., 2022
Abstract Plants in nature commonly encounter combined stress scenarios. The response to combined stressors is often unpredictable from the response to single stresses. To address stress interference in roots, we applied salinity, heat, and high light to hydroponically grown sugar beet. Two main patterns of metabolomic acclimation were apparent.
Pedro García‐Caparrós, Lara Vogelsang, Marcus Persicke, Markus Wirtz, Vijay Kumar, Karl‐Josef Dietz   +5 more
wiley   +1 more source

Automatisierte Probenfiltration zur Analyse intrazellulärer Metaboliten bei höheren Biomassekonzentrationen Automated Fast Filtration for the Analysis of Intracellular Metabolites at Higher Biomass Concentrations

Chemie Ingenieur Technik, Volume 94, Issue 6, Page 864-872, June 2022., 2022
Eine automatisierte Anlage zur Schnellfiltration ermöglicht die Bestimmung intrazellulärer Metaboliten bei höheren Biomassekonzentrationen für Stoffwechseluntersuchungen, beispielhaft dargestellt anhand der Untersuchung einer Modifikation der Aspartokinase in Corynebacterium glutamicum. Zudem weist sie den Weg zu einer Filtration im Sekundenbereich für
Enrico Hans, An‐Ping Zeng
wiley   +1 more source

GC/MS‐Based Urine Metabolomics Study on the Ameliorative Effect of Xanthoceras sorbifolia Extract on Alzheimer’s Disease in Mice

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
The cause of Alzheimer’s disease, the most common type of dementia today, is still unclear, and in current research, there are no drugs that work relatively well. Therefore, the study for new drugs to treat Alzheimer’s disease is an urgent research need. Research on the improvement of Alzheimer’s disease with extracts of Xanthoceras sorbifolia has been
Rui Han, Min Wang, Li Wang, Yichen Zhang, Xin Li, Yijun Hou, Jing Yan, Xiaojing Pan, M. Maulidiani   +8 more
wiley   +1 more source

Is serum biotinidase enzyme activity a potential marker of perturbed glucose and lipid metabolism?

JIMD Reports, Volume 57, Issue 1, Page 58-66, January 2021., 2021
Abstract Glycogen storage diseases (GSDs) belong to the group of inborn errors of carbohydrate metabolism. Hepatic GSDs predominantly involve the liver and most present with hepatomegaly. Biochemically they show known disturbances in glucose and fatty acids metabolism, namely fasting hypoglycaemia and increased triglycerides.
Patrick Forny, Patricie Burda, Peter Bode, Marianne Rohrbach   +3 more
wiley   +1 more source

A model of photosynthetic CO2 assimilation in C-3 leaves accounting for respiration and energy recycling by the plastidial oxidative pentose phosphate pathway [PDF]

, 2023
circle Recently, we reported estimates of anaplerotic carbon flux through the oxidative pentose phosphate pathway (OPPP) in chloroplasts into the Calvin- Benson cycle.
Augusti, Angela, Schleucher, Juergen, Wieloch, Thomas   +2 more
core  

TIGAR regulates DNA damage and repair through pentosephosphate pathway and Cdk5-ATM pathway [PDF]

Scientific Reports, 2015
AbstractPrevious study revealed that the protective effect of TIGAR in cell survival is mediated through the increase in PPP (pentose phosphate pathway) flux. However, it remains unexplored if TIGAR plays an important role in DNA damage and repair. This study investigated the role of TIGAR in DNA damage response (DDR) induced by genotoxic drugs and ...
Hong-Pei Yu, Jia-Ming Xie, Bin Li, Yi-Hui Sun, Quan-Geng Gao, Zhi-Hui Ding, Hao-Rong Wu, Zheng-Hong Qin   +7 more
openaire   +2 more sources

Clostridium sticklandii, a specialist in amino acid degradation:revisiting its metabolism through its genome sequence [PDF]

, 2010
Background Clostridium sticklandii belongs to a cluster of non-pathogenic proteolytic clostridia which utilize amino acids as carbon and energy sources. Isolated by T.C.
Nuria Fonknechten, Sébastien Chaussonnerie, Sabine Tricot, Aurélie Lajus, Jan R Andreesen, Nadia Perchat, Eric Pelletier, Michel Gouyvenoux, Valérie Barbe, Marcel Salanoubat, Denis Le Paslier, Jean Weissenbach, Georges N Cohen, Annett Kreimeyer   +13 more
core   +2 more sources

Glucose‐6‐Phosphate Dehydrogenase of Trypanosomatids: Characterization, Target Validation, and Drug Discovery

Molecular Biology International, Volume 2011, Issue 1, 2011., 2011
In trypanosomatids, glucose‐6‐phosphate dehydrogenase (G6PDH), the first enzyme of the pentosephosphate pathway, is essential for the defense of the parasite against oxidative stress. Trypanosoma brucei, Trypanosoma cruzi, and Leishmania mexicana G6PDHs have been characterized.
Shreedhara Gupta, Mariana Igoillo-Esteve, Paul A. M. Michels, Artur T. Cordeiro, Hemanta K. Majumder   +4 more
wiley   +1 more source