Results 61 to 70 of about 95,493,239 (211)

Pentraxin-3 – a potential biomarker in ANCA-associated vasculitis

Scandinavian Journal of Rheumatology, 2022
The aim of this study was to investigate pentraxin-3 (PTX3) as a potential biomarker of inflammatory activity in patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) at baseline and 6 month follow-up in a longitudinal cohort.Plasma PTX3 levels were measured in 79 newly diagnosed or relapsing AAV patients at baseline and
AD Jonasdottir, A Antovic, AR Qureshi, A Nordin, V Malmström, I Gunnarsson, A Bruchfeld   +6 more
openaire   +3 more sources

In silico analysis revealed high-risk single nucleotide polymorphisms in human pentraxin-3 gene and their impact on innate immune response against microbial pathogens

Frontiers in Microbiology, 2016
Pentraxin-3 (PTX-3) protein is an evolutionary conserved protein that acts as a soluble pattern-recognition receptor for pathogens and plays important role in innate immune response.
Raman eThakur, Jata eShankar
doaj   +1 more source

Local Low‐Frequency Vibration Enhances Wound‐Healing and Modulates Cellular Senescence in Tissues and Exudates in a Hyperglycemic Rat Model

The Journal of Dermatology, EarlyView.
ABSTRACT Hard‐to‐heal wounds, such as diabetic foot ulcers and pressure injuries, pose major clinical challenges due to chronic inflammation and cellular senescence. Cellular senescence‐associated mechanisms, including stress‐responsive p53/p21 signaling and senescence‐associated secretory phenotype‐related inflammation, contribute to impaired wound ...
Daijiro Haba, Chihiro Takizawa, Qi Qin, Sanai Tomida, Ai Horinouchi, Hiromi Sanada, Gojiro Nakagami   +6 more
wiley   +1 more source

Plasma pentraxin 3 levels in preeclamptic patients

Clinical and Experimental Obstetrics & Gynecology, 2015
The authors evaluated plasma pentraxin 3 (PTX 3) levels in preeclamptic patients and determined the relationship between albuminuria and plasma PTX 3 levels. During a period of one year, 29 patients with severe or mild preeclampsia and 49 healthy pregnant women were included in the cross-sectional study. The two groups were compared each other with PTX
O, Turkmen, S, Mollaoglu, G, Goynumer, B, Isbilen   +3 more
openaire   +2 more sources

Shared dysregulation of complement and phosphorylation pathways in the cerebrospinal fluid of encephalitis, Aicardi–Goutières syndrome, and autism

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To identify shared and disorder‐specific molecular alterations across encephalitis, Aicardi–Goutières syndrome (AGS), and autism spectrum disorder (ASD) using cerebrospinal fluid (CSF) proteomics. Method In this cross‐sectional case–control study, mass‐spectrometry‐based proteomics was performed on archived CSF samples collected between ...
Omar H. Shadid, Peter G. Hains, Velda X. Han, Jingya Yan, Michael Griffiths, Ignatius Pang, Sushil Bandodkar, Phillip J. Robinson, Russell C. Dale   +8 more
wiley   +1 more source

The Long Pentraxin 3 contributes to triple negative breast cancer stemness tumorigenicity.

, 2021
The Long Pentraxin 3 contributes to triple negative breast cancer stemness tumorigenicity.The Long Pentraxin 3 contributes to triple negative breast cancer stemness ...
CHURRUCA SCHUIND, ANDER
core  

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Evaluation of serum pentraxin–3 (PTX–3) levels in cats with neoplasia

Revista Científica
Pentraxin–3 is a multifunctional protein implicated in human oncology due to its roles in regulating inflammation, angiogenesis, and tumor progression. However, its potential as a biomarker in feline oncology remains insufficiently investigated.
Nihan Avci, Melek Aydemir, Fehmiye Gumus-Ozdil , Orhan Yavuz, Hidayet Metin Erdogan   +4 more
doaj   +1 more source

Microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases

Periodontology 2000, EarlyView.
Abstract Objectives To critically evaluate the current evidence on microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases, with emphasis on their biological relevance, potential clinical utility, and current translational limitations.
Su Sheng Quach, Ausra Ramanauskaite, Sašo Ivanovski, Pingping Han, Frank Schwarz, Emilio A. Cafferata   +5 more
wiley   +1 more source

The Long Pentraxin 3 and Its Role in Autoimmunity

Seminars in Arthritis and Rheumatism, 2009
To review the physiological and physiopathological roles of pentraxin 3 (PTX3), focusing on autoimmunity and vascular pathology.A systematic literature review using the keywords "pentraxin 3," "innate immunity," "apoptosis," "autoimmunity," and "endothelial dysfunction" from 1990 to 2007 was performed.
Ortega-Hernandez, Oscar-Danilo, Bassi, Nicola, Shoenfeld, Yehuda, Anaya, Juan-Manuel   +3 more
openaire   +2 more sources