Results 21 to 30 of about 88,108,181 (162)

The Role of Pentraxin 3 in Aspergillosis: Reality and Prospects [PDF]

Mycobiology, 2020
Pentraxin 3 (PTX3) is a soluble pattern recognition receptor (PRR), which is produced by several kinds of cells, such as neutrophils, dendritic cells, macrophages, and epithelial cells.
Yuening Kang, Yuetian Yu, Liangjing Lu
doaj   +3 more sources

Diagnostic Value of Pentraxin-3 in COVID-19 Pediatric Patients [PDF]

Bagcilar Medical Bulletin
Objective: Many studies have investigated the relationship of hematological, biochemical, immunological, and inflammatory markers with clinical severity during severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection.
Didem Öcal Topçu, Kamil Şahin, Murat Elevli, İbrahim Yılmaz, Gülşen Akkoç   +4 more
doaj   +2 more sources

Pentraxin-3 as a novel biomarker in predicting outcomes of nosocomial pneumonia: a prospective observational study [PDF]

Monaldi Archives for Chest Disease
Pneumonia, among all nosocomial infections, is known for its dismal prognosis, imposing substantial morbidity and mortality. While the diagnostic performance of various blood biomarkers has undergone scrutiny, their prognostic implications remain ...
Isha Garg, Nishant Kumar Chauhan, Harsh Vardhan, Shrimanjunath Sankanagoudar, Naveen Dutt, Gopal Durgeshwar, Hariharan Iyer, Nikhil Kothari, Ravisekhar Gadepalli, Deepak Kumar   +9 more
doaj   +2 more sources

Pentraxin-3 and the pathogenesis of preeclampsia [PDF]

Hypertension Research, 2020
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Angeli, Fabio, Angeli, Enrica, Trapasso, Monica, Verdecchia, Paolo   +3 more
openaire   +3 more sources

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Hepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli, Silvia Marchianò, Cristina di Giorgio, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Bianca Fiorillo, Valentina Sepe, Bruno Catalanotti, Chiara Cassiano, Maria Chiara Monti, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +13 more
wiley   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source

Perbedaan Kadar Pentraxin 3 pada Penderita Hepatitis B Kronis dengan Cirrosis dan Tanpa Cirrosis [PDF]

, 2023
This study aims to see differences in pentraxin 3 levels in chronic hepatitis B sufferers with cirrosis and without cirrosis. The method uses cross sectional consecutive sampling.
Loesnihari, Ricke, Sasmita, Afrianda Wira, Sungkar, Taufik   +2 more
core   +1 more source

The Role of Pentraxin 3 in Gastrointestinal Cancers

Cancers, 2023
Gastrointestinal cancers have become a huge problem worldwide as the number of new cases continues to increase. Due to the growing need to explore new biomarkers and therapeutic targets for the detection and treatment of cancerous lesions, we sought to elucidate the role of Pentraxin-3 in the progression of cancerous lesions, as it is involved in the ...
Monika Zajkowska, Barbara Mroczko
openaire   +2 more sources

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Regulation of pentraxin-3 by antioxidants [PDF]

British Journal of Anaesthesia, 2009
Pentraxin-3 (PTX3) may be a useful biomarker in sepsis, but its regulatory mechanisms are still unclear. Oxidative stress is well defined in patients with sepsis and has a role in regulation of inflammatory pathways which may include PTX3. We undertook an in vitro study of the effect of antioxidants on regulation of PTX3 in endothelial cells combined ...
Hill, A L, Lowes, D A, Webster, N R, Sheth, C C, Gow, N A R, Galley, H F   +5 more
openaire   +3 more sources