Results 81 to 90 of about 88,108,181 (162)
Proteoglycan Research, Volume 4, Issue 4, October 2026.ABSTRACT Hyaluronan (HA) is an ubiquitous non‐sulfated glycosaminoglycan with unique physicochemical and biological properties that underpin its essential roles in tissue homeostasis, repair, and diseases. First identified in the vitreous humor of the eye, HA has a long‐standing history in ophthalmology as a key component of ophthalmic visco‐surgical ...
Sudhir Verma +3 more
wiley +1 more source
Prognostic Value of Pentraxin-3 and Procalcitonin in Neonatal Sepsis
Pakistan Armed Forces Medical JournalObjective: To evaluate the prognostic value of Pentraxin-3 and Procalcitonin in neonatal sepsis. Study Design: Prospective observational study. Place and Duration of Study: Neonatal Intensive Care Unit, Pakistan Aeronautical Complex Hospital, Kamra,
Mudassar Rubab +3 more
doaj +1 more source
Cancer Medicine, Volume 15, Issue 9, September 2026.ABSTRACT Studies have demonstrated that the nervous system plays an important role in cancer progression. Nevertheless, the effect of mesenchymal stem cells (MSCs) on cancer has yielded conflicting results. In this study, we discovered that cancer‐derived MSCs (CA‐MSCs) not only exhibit the properties of neural stem cells (NSCs) but also express a ...
Liu Yongjun +11 more
wiley +1 more source
Pentraxin-3 regulates the inflammatory activity of macrophages
Biochemistry and Biophysics Reports, 2016 Pentraxin-3 (PTX3) reportedly has protective roles in atherosclerosis and myocardial infarction, and is a useful biomarker of vascular inflammation. However, the detailed functions of PTX3 in inflammation are yet to be elucidated. This study aimed to investigate the function of PTX3 in macrophages.PMA-treated THP-1 cell line (THP-1 macrophage) and ...
Aya Shiraki +5 more
openaire +3 more sources
Journal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.ABSTRACT Phosphomannomutase deficiency (PMM2‐CDG), the most common congenital disorder of glycosylation (CDG), is characterized by multisystem involvement and a lack of disease‐modifying therapies. While previous transcriptomic studies have uncovered disrupted cellular pathways, the functional consequences of these alterations remain poorly understood.
Diana Gallego +10 more
wiley +1 more source
The Impact of Pentraxin 3 on Crohn’s Disease Phenotype
International Journal of Molecular SciencesPentraxin 3 [PTX3] is an acute-phase protein playing an important role in the regulation of the humoral arm of immune response. As one of the molecules from the conservative family of pentraxins, PTX3 is a soluble mediator involved in the transduction of pro-inflammatory signals between immunocompetent cells. Additionally, recognizing damage-associated
Anna Kofla-Dlubacz +4 more
openaire +3 more sources
Serum interleukin-35 and pentraxin-3 levels in patients with mild acute pancreatitis
, 2019 Introduction Interleukin-35 (IL-35) is a newly defined potent anti-inflammatory cytokine that is predominantly produced by regulatory T cells, and pentraxin-3 belongs to the acute-phase proteins.
Nazlıgül, Yaşar +12 more
core +1 more source
Protein Science, Volume 35, Issue 9, September 2026.Abstract Accurate identification of epitope residues is essential for developing biopharmaceuticals and understanding the mechanisms of immune recognition. However, experimental approaches for residue‐level epitope mapping remain time‐consuming and labor‐intensive, while accurate computational prediction of protein–protein interfaces remains ...
Kihoon Kim +4 more
wiley +1 more source
The inflammatory protein Pentraxin 3 in cardiovascular disease
Immunity & Ageing, 2016 The acute phase protein Pentraxin 3 (PTX3) plays a non-redundant role as a soluble pattern recognition receptor for selected pathogens and it represents a rapid biomarker for primary local activation of innate immunity and inflammation. Recent evidence indicates that PTX3 exerts an important role in modulating the cardiovascular system in humans and ...
Fornai, Francesco +9 more
openaire +2 more sources
Gastric bypass-induced weight loss alters obesity-associated patterns of plasma pentraxin-3 and systemic inflammatory markers [PDF]
, 2016 Systemic inflammation contributes to obesity-associated complications. The short pentraxin C-reactive protein (CRP) is a validated inflammatory marker, whereas long pentraxin-3 (PTX3) limits inflammation and is adaptively stimulated by proinflammatory ...
PALMISANO, SILVIA +9 more
core +1 more source