Results 51 to 60 of about 26,526,867 (295)

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

How patterns of injecting drug use evolve in a cohort of people who inject drugs [PDF]

, 2015
This research found an overall movement away from street based drug purchasing and drug use, towards more activity in private settings, which has important implications for the harms experienced by people who inject drugs.
Alison Ritter, Jonathan P. Caulkins, Nick Scott, Paul Dietze   +3 more
core  

Managing tuberculosis in people who use and inject illicit drugs

Bulletin of the World Health Organization, 2013
People who use and inject illicit drugs are at high risk of contracting tuberculosis, whether or not they are infected with the human immunodeficiency virus (HIV). Studies conducted before and after the emergence of HIV infection show that, when compared with the general population, people who use illicit drugs have a higher risk not just of getting ...
Haileyesus Getahun, Annabel Baddeley, Mario Raviglione   +2 more
openaire   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A mixed-methods analysis of risk-reduction strategies adopted by syringe services program participants and non-syringe services program participants in New York City

Harm Reduction Journal, 2023
Background Since the emergence of fentanyl in the drug market, syringe services programs (SSPs) have been at the forefront of providing life-saving tools such as naloxone and fentanyl test strips to people who use drugs (PWUD).
Nisha Beharie, Adelya Urmanche, Alex Harocopos   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Patterns of e-cigarette use among a sample of people who regularly use ecstasy and related drugs in Sydney NSW, 2014-2022 [PDF]

, 2023
The Ecstasy and Related Drug Reporting System (EDRS) has been monitoring patterns of e-cigarette use and behaviour since 2014. Thus, this bulletin aims to examine the past six-month use of any e-cigarettes (prescribed and non-prescribed) among a sample ...
Chandrasena, Udesha, Sutherland, Rachel ; https://orcid.org/   +1 more
core   +1 more source

Another frontier for harm reduction: contraceptive needs of females who inject drugs in Estonia, a cross-sectional study

Harm Reduction Journal, 2018
Background Despite increasing contraceptive availability, unintended pregnancy remains a global problem. Developing strategies to reverse this trend and increasing occurrence of withdrawal syndrome among newborn children of females currently injecting ...
Anneli Uusküla, Mait Raag, Sigrid Vorobjov, Don Des Jarlais   +3 more
doaj   +1 more source

Stimulant safe supply: a potential opportunity to respond to the overdose epidemic

Harm Reduction Journal, 2020
Background Occurring against the backdrop of an overdose crisis, stimulant use and stimulant-involved deaths in North America are increasing at an alarming rate.
Taylor Fleming, Allison Barker, Andrew Ivsins, Sheila Vakharia, Ryan McNeil   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source