Results 61 to 70 of about 1,466,572 (302)

Observational study on the consumption of recreational drugs and alcohol by Swiss travelers. [PDF]

, 2014
BACKGROUND: Studies carried out on specific travelers' groups such as students describe an increase in the consumption of alcohol and drugs during travel and vacation time.
de Vallière, S., Genton, B., Klunge-de Luze, C., Senn, N.   +3 more
core   +3 more sources

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Prevalence and correlates of violence among sexual and injecting partners of people who inject drugs living with HIV in Kenya: a cross-sectional study

Harm Reduction Journal, 2023
Background In Kenya, violence is common among people who inject drugs (PWID) living with HIV and their sexual and injecting partners and may lead to decreased uptake of HIV services, increased HIV risk behaviors, and increased HIV transmission.
Sai Win Kyaw Htet Aung, Hanley Kingston, Loice W. Mbogo, Betsy Sambai, Aliza Monroe-Wise, Natasha T. Ludwig-Barron, David Bukusi, William Sinkele, Esther Gitau, Sarah Masyuko, Joshua T. Herbeck, Carey Farquhar, Brandon L. Guthrie   +12 more
doaj   +1 more source

(Re)politicizing harm reduction: Poststructuralist thinking to challenge the medicalization of harms among people who use drugs

Aporia, 2021
Poststructuralism, with its critical interpretations of knowledge, discourse, truth, and power, offers a set of compelling analytic tools for disentangling and deconstructing the ways in which health-related phenomena exist and are understood. This paper
Trevor Goodyear
doaj   +1 more source

Fentanyl self-testing outside supervised injection settings to prevent opioid overdose: Do we know enough to promote it? [PDF]

, 2018
Since 2013, North America has experienced a sharp increase in unintentional fatal overdoses: fentanyl, and its analogues, are believed to be primarily responsible.
Australian Injecting & Illicit Drug Users League, Catherine R. McGowan, Centers for Disease Control and Prevention, Ciccarone, Ciccarone, Ciccarone, Clark, Compton, Cressman, Daniulaityte, European Monitoring Centre for Drugs and Drug Addiction, Fairbairn, Frank, Friedman, Gladden, Harris, Human Rights Watch, Johns Hopkins Bloomberg School of Public Health, Jozaghi, Lucy Platt, Lysyshyn, Magdalena Harris, Marshall, Massey, McGowan, Messac, Mounteney, Murray, Neira-Leon, O'Donnell, Quest, Rhodes, Rhodes, Rhodes, Rhodes, Schneider, Seth, Shaheen, Socias, Stewart, The Vancouver Sun, Tim Rhodes, United Nations Office on Drugs and Crime, United States Drug Enforcement Administration, United States Drug Enforcement Administration, Vivian Hope, Winstock   +46 more
core   +2 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

National and Regional Estimates of the Prevalence of Opiate and/or Crack Cocaine use 2008-09: A summary of key findings [PDF]

, 2010
<p>This report summarises the results of a follow-up study to a three year project to estimate the prevalence of ‘problem drug use’ (defined as use of opiates and/or crack cocaine) nationally (England only), regionally and locally.
Casey, J., Gannon, M., Hay, G., Millar, T.   +3 more
core  

Managing tuberculosis in people who use and inject illicit drugs

Bulletin of the World Health Organization, 2013
People who use and inject illicit drugs are at high risk of contracting tuberculosis, whether or not they are infected with the human immunodeficiency virus (HIV). Studies conducted before and after the emergence of HIV infection show that, when compared with the general population, people who use illicit drugs have a higher risk not just of getting ...
Haileyesus Getahun, Annabel Baddeley, Mario Raviglione   +2 more
openaire   +4 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Benefits and barriers: a rapid-ethnographic study on the perspectives of potential and actual clients of Athens’ drug consumption room

Harm Reduction Journal
Background In April 2022, a new Drug Consumption Room (DCR) opened in Athens’ city centre. To date, no qualitative research has evaluated the operational strengths and weaknesses of the site from the viewpoint of people who use drugs locally, including ...
Benjamin D. Scher, Nikolaos Poulopoulos, Christos Anastasiou, Benjamin W. Chrisinger, David K. Humphreys, Gillian W. Shorter   +5 more
doaj   +1 more source