Results 101 to 110 of about 43,421 (258)
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Accurate modeling of the structures of protein–protein complexes and other biomolecular interactions represents a longstanding and important challenge for computational biology. The Critical Assessment of PRedicted Interactions (CAPRI) experiment has served for over two decades as a key means to assess and compare current approaches and ...
Ragul Gowthaman +4 more
wiley +1 more source
Performance of pyDock in 8th CAPRI: Energy‐Based Scoring Applied to Docking and AlphaFold Models
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT The 8th CAPRI edition has shown a significant evolution in the field of protein–protein complex structure prediction. We have participated in all 11 targets proposed in this edition, involving domain‐domain, protein–protein, protein‐peptide, and protein‐DNA interactions, including homo‐ and hetero‐meric interfaces.
Luis Angel Rodríguez‐Lumbreras +5 more
wiley +1 more source
Sustainable Development, EarlyView.ABSTRACT Digitalisation has become an increasingly prominent topic in research on regional sustainable development. As academic attention to its relationship with Sustainable Development Goals expands, the thematic configuration and structural evolution of this research domain remain fragmented.
Georgiana Alina Crisan +3 more
wiley +1 more source
Small, EarlyView.A multifunctional nanodiamond conjugate carrying a blue light‐activated carbon monoxide‐releasing molecule and an EGFR‐targeting peptide enables efficient, targeted CO delivery in vitro and in vivo. Upon photoactivation, the particles induce cancer‐specific cytotoxicity and significantly suppress tumor growth and lymph node metastasis in a head and ...
Harsh Nitin Dongre +12 more
wiley +1 more source
Smart Molecules, EarlyView.The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou +4 more
wiley +1 more source
IEEJ Transactions on Electrical and Electronic Engineering, EarlyView.Most countries, including Japan, are focused on achieving net‐zero greenhouse gas (GHG) emissions by 2050, which requires quick action. Despite the increasing level of renewable power generation in power grids, fossil fuel power plants still have a significant role in producing GHG emissions, causing serious environmental issues.
Kadyrbek Kozhobekov +4 more
wiley +1 more source
Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity
VIEW, EarlyView.Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin +3 more
wiley +1 more source
The UK Clean Air Act at 70: An interdisciplinary analysis of historical air quality change
Weather, EarlyView.2026 marks the 70th anniversary of the first UK Clean Air Act, a pivotal moment for air quality in modern British history. Previous narratives on this legislation have largely centred on pollution in London and monodisciplinary perspectives. This article integrates historical research with reconstructed estimates of PM2.5 concentrations to spotlight ...
Kathy Davies +2 more
wiley +1 more source
Journal of Synchrotron Radiation, EarlyView.A 4D X‐ray computed tomography experimental campaign was carried out on a porous carbonate rock to investigate the link between initial porosity and deformation modes. This paper presents the experiment and the methods used to explore this relationship.The study of the mechanical behaviour of carbonate rocks has benefited from the evolution of ...
Catherine Doré-Ossipyan +7 more
wiley +1 more source