Results 111 to 120 of about 43,421 (258)

A Novel Antioxidant Peptide Cath‐Np Derived from Nanorana parkeri Attenuates UVB‐Induced Skin Photodamage in Mice

Integrative Zoology, EarlyView.
Schematic representation of Cath‐Np as an antioxidant suppressing acute skin damage caused by ultraviolet B (UVB) radiation in mice. Cath‐Np inhibits the activation of p53 and mitogen‐activated protein kinase pathways while it activates the Nrf2 pathway by its strong antioxidant effects, and accordingly suppresses the expression of inflammatory factors
Hang Liao, Xiaoxiao Shen, Jinwei Chai, Kai wang, Jiena Wu, Jianxi Yang, Ming Chen, Guoxiang Mo, Xueqing Xu   +8 more
wiley   +1 more source

Amphibian‐Derived Peptide OA‐AL14 Alleviates UVB‐Induced Skin Photoaging via Autophagy Activation Mediated by the AMPK/mTOR Pathway

Integrative Zoology, EarlyView.
The schematic diagram illustrates that the amphibian‐derived peptide OA‐AL14 protects against UVB‐induced skin photoaging through a dual mechanism: activating the Nrf2 pathway to counteract oxidative stress and modulating the AMPK/mTOR axis to induce protective autophagy. ABSTRACT Skin photoaging, primarily driven by ultraviolet B (UVB) radiation, is a
Ying Peng, Yutong Wu, Zhe Fu, Zijian Kang, Qiuye Jia, Wenbi Zhao, Ziyi Wang, Yuexi Liu, Ruijie Zhang, Yuansheng Li, Zeqiong Ru, Wenrou Su, Naixin Liu, Yilin Li, Saige Yin, Ying Wang, Xinwang Yang   +16 more
wiley   +1 more source

How do visual and conceptual factors predict the object content in typical scene drawings?

British Journal of Psychology, EarlyView.
Abstract Imagine you draw a typical bedroom, your choice of objects is likely to depend on visual occurrence statistics (i.e. the objects present in previously encountered bedrooms) and semantic relations between objects and scenes (i.e. the semantic relationship between the bedroom and its constituent objects).
Gongting Wang, Ilker Duymaz, Matthew J. Foxwell, Micha Engeser, David Pitcher, Radoslaw M. Cichy, Daniel Kaiser   +6 more
wiley   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Feasibility and Efficacy of Culturally Tailored Parenting Programme Delivered In‐Person vs. Zoom for Korean Americans: Towards Equitable Child Development

Child &Family Social Work, EarlyView.
ABSTRACT First‐generation Korean Americans face parenting challenges due to language and cultural differences, impacting children's development. We evaluated the culturally tailored Ottuki Parenting Program, comparing its efficacy in‐person versus via Zoom.
Sou Hyun Jang, Jaeeun Lee, Eunjung Kim, Rachel Lee, Younghee Cho, Claire Jungyoun Han, Joon Ho Yu, Sangho Kim, Jun Rim Park, Young Oak Choi, Jung‐A Chu, Sook Kyung Park   +11 more
wiley   +1 more source

Embedding memory in coarse-grained Hamiltonian systems

Physical Review Research
Memory effects are an unavoidable consequence of coarse-graining Hamiltonian many-body systems. Although Markovian embeddings with auxiliary variables are widely used to approximate such dynamics, their consistency with the exact projected microscopic ...
Pep Español
doaj   +1 more source

Real‐world completion of diabetes self management education and its impact on patient‐reported outcomes: A scoping review

Diabetic Medicine, EarlyView.
Abstract Aims Diabetes self management education (DSME) is recommended for type 2 diabetes, with completion widely accepted as ≥60% engagement. This review utilising PRISMA extension for scoping reviews maps the literature on the impact of full and partial completion of DSME on patient‐reported outcomes (PROMs) versus a control.
Gemma Lewis, David M. Hughes, Greg Irving, John Wilding, Kevin Hardy   +4 more
wiley   +1 more source

Comparative General Relationship Education Classroom Experiences Between Sexual and Gender Diverse and Cisgender Heterosexual Individuals

Family Relations, EarlyView.
ABSTRACT Objective This lesson from the field study describes findings and lessons learned from examining similarities and differences in classroom environments and experiences, and their influence on relationship quality changes for sexual and gender diverse (SGD) and cisgender heterosexual individuals who attended a general Couple Relationship ...
Menglin Wei‐Wise, Francesca Adler‐Baeder, Joshua R. Novak, Julianne M. McGill   +3 more
wiley   +1 more source

Mechanistic insights into HapC: A key enzyme in prodiginine biosynthesis in Hahella chejuensis

The FEBS Journal, EarlyView.
HapC catalyzes prodiginine biosynthesis through coordinated movements of its ATP‐binding, substrate‐binding, and catalytic‐swivel domains. The enzyme shows tolerance toward short‐chain MAP analogs, and docking analyses reveal key residues and structural features underlying its substrate flexibility.
Yueh‐Te Chan, Aden Dhana Rizkita, Hsin‐Ju Hsieh, Shu‐Fang Hsu, Tony Eight Lin, Wei‐Jan Huang, Kai‐Cheng Hsu, Sheila Nathan, Peiching Chang, Andrew H.‐J. Wang, Cheng‐Chung Lee   +10 more
wiley   +1 more source

Common pathways and outliers in glucose catabolism across Trypanosomatidae

The FEBS Journal, EarlyView.
Trypanosomatid parasites, including Trypanosoma sp., Leishmania sp., Phytomonas sp., and Vickermania sp., share a common motif: a metabolism built around the glycosome, a unique peroxisome‐derived organelle housing the first steps of glycolysis. Yet, these organisms have evolved remarkably diverse strategies to catabolize glucose, excreting distinct ...
Fred R. Opperdoes, Mayke B. Alencar, Ariel M. Silber, Ingrid Škodová‐Sveráková, Kristína Záhonová, Vyacheslav Yurchenko   +5 more
wiley   +1 more source