Kinetics of pepsin-induced hydrolysis and the coagulation of milk proteins
Journal of Dairy Science, 2022 : Hydrolysis-induced coagulation of casein micelles by pepsin occurs during the digestion of milk. In this study, the effect of pH (6.7–5.3) and pepsin concentration (0.110–2.75 U/mL) on the hydrolysis of κ-casein and the coagulation of the casein ...
Mengxiao Yang +5 more
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PLoS ONE, 2020 Pepsin plays an important role in laryngopharyngeal reflux (LPR), a risk factor for the development of hypopharyngeal squamous cell carcinomas (HPSCC). However, the role of pepsin in HPSCC is not clear.
Kai Niu +8 more
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Sensors, 2020 Salivary pepsin is a promising marker for the non-invasive diagnosis of laryngopharyngeal reflux (LPR). For reliable results regarding pepsin in saliva, it is critical to standardize the collection, storage, and pre-processing methods.
Young Ju Lee +5 more
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Research note: Extraction, purification, physicochemical, and biochemical properties of pepsin isolated from geese forestomachs fed under intensive and extensive conditions [PDF]
Poultry ScienceThis Research Note reports the isolation and basic characterization of pepsin obtained from the forestomach of geese raised under intensive and extensive rearing systems.
Pelin Beyazgul +7 more
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Pepsin promotes IL-8 signaling-induced epithelial–mesenchymal transition in laryngeal carcinoma
Cancer Cell International, 2019 Background Laryngopharyngeal reflux (LPR), with its increasing morbidity, is attracting considerable attention. In recent years, the causal role between LPR and laryngeal carcinoma has been debated.
Jia-Jie Tan +5 more
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Combined laryngopharyngeal reflux and obstructive sleep apnea (CLOSA) – Salivary pepsin test for laryngopharyngeal reflux in obstructive sleep apnea patients [PDF]
Tzu Chi Medical JournalObjectives: Reflux disease including gastroesophageal reflux and laryngopharyngeal reflux (LPR) is often found in obstructive sleep apnea (OSA) patients. Endoscopic examination is a gold standard diagnosis for reflux disease.
Shih-Chieh Shen +8 more
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Revisiting the enzymatic kinetics of pepsin using isothermal titration calorimetry
Food Chemistry, 2018 Pepsin is the first protease that food proteins encounter in the digestive tract. However, most of the previous studies on the enzymatic kinetics of pepsin were based on the hydrolysis of small synthetic peptides, due to the limitations in methodology ...
Qi Luo, Anja E M Janssen
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Pepsin diffusivity in whey protein gels and its effect on gastric digestion
Food Hydrocolloids, 2017 Protein is essential to human health, but its digestion kinetics in varied structures are not yet well understood. We previously found different kinetics of protein hydrolysis in solution and in gels, and we hypothesized that the difference stemmed from ...
Qi Luo
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Food & Function, 2021 The activity of pepsin, the gastric protease, is generally considered to be negligible for pH ≥ 4, based on the results obtained with a few purified globular proteins.
Lea Salelles +2 more
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The In Vitro Effect of Acidic-Pepsin on Nuclear Factor KappaB Activation and Its Related Oncogenic Effect on Normal Human Hypopharyngeal Cells. [PDF]
PLoS ONE, 2016 Extra-esophageal carcinogenesis has been widely discussed in relation to the chronic effects of laryngopharyngeal reflux and most prominently with pepsin historically central to this discussion.
Clarence T Sasaki +2 more
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