European Archives of Oto-Rhino-Laryngology, 2021 Laryngopharyngeal reflux disease (LPRD) is a general term for the reflux of gastroduodenal contents into the laryngopharynx, oropharynx and even the nasopharynx, causing a series of symptoms and signs.
Yading Li +12 more
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Effects of pepsin and pepstatin on reflux tonsil hypertrophy in vitro. [PDF]
PLoS ONE, 2018 There is evidence that pepsin can aggravate tonsil hypertrophy. Pepstatin is a potent inhibitor of pepsin activity and could protect patients against reflux tonsil hypertrophy by inhibiting pepsin.
Jin Hyun Kim +4 more
doaj +1 more source
Analyzing pepsin degradation assay conditions used for allergenicity assessments to ensure that pepsin susceptible and pepsin resistant dietary proteins are distinguishable. [PDF]
PLoS ONE, 2017 The susceptibility of a dietary protein to proteolytic degradation by digestive enzymes, such as gastric pepsin, provides information on the likelihood of systemic exposure to a structurally intact and biologically active macromolecule, thus informing on
Rong Wang +8 more
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Variability and accuracy of multiple saliva pepsin measurements in laryngopharyngeal reflux patients
Journal of Otolaryngology - Head and Neck Surgery, 2023 Objective To study the variability and diagnostic value of multiple salivary pepsin measurements in the detection of laryngopharyngeal reflux (LPR).
Jerome R. Lechien, Francois Bobin
doaj +1 more source
Extra-Esophageal Pepsin from Stomach Refluxate Promoted Tonsil Hypertrophy. [PDF]
PLoS ONE, 2016 Gastroesophageal reflux is associated with numerous pathologic conditions of the upper aerodigestive tract. Gastric pepsin within reflux contributes to immunologic reactions in the tonsil.
Jin Hyun Kim +7 more
doaj +1 more source
Separation of pepsin I, pepsin II A, pepsin II B, and pepsin III from human gastric mucosa [PDF]
American Journal of Physiology-Legacy Content, 1963 Extracts of human gastric mucosa have been fractionated on diethylaminoethyl cellulose to yield three precursors of proteolytic enzymes active at low pH which have been called pepsinogen I, pepsinogen II, and pepsinogen III. Pepsinogen I has been found in the mucosa from all parts of the stomach examined as well as in the proximal duodenum. Pepsinogen
M J, SEIJFFERS, H L, SEGAL, L L, MILLER
openaire +2 more sources
Protein acidification and hydrolysis by pepsin ensure efficient trypsin-catalyzed hydrolysis.
Food & Function, 2021 Enzyme-catalysed hydrolysis is important in protein digestion. Protein hydrolysis is initiated by pepsin at low pH in the stomach. However, pepsin action and acidification happen simultaneously to gastric emptying, especially for liquid meals. Therefore,
Andrea Rivera Del Rio +3 more
semanticscholar +1 more source
Investigation of antifungal activity of lactic acid bacteria isolated from sorghum, corn and barley sour doughs against Aspergillus flavus, Penicillium expansum and Rhizopus coriniformis molds [PDF]
مجله بیوتکنولوژی کشاورزی, 2022 Objective: In recent years, the use of biological methods to control the activity of molds with the help of lactic acid bacteria and their metabolites has received much attention.
Barat Ali Zarei Yam +3 more
doaj +1 more source
THE ESTIMATION OF PEPSIN, TRYPSIN, PAPAIN, AND CATHEPSIN WITH HEMOGLOBIN
The Journal of General Physiology, 1938 In the hemoglobin method for the estimation of proteinase, denatured hemoglobin is digested under standard conditions, the undigested hemoglobin is precipitated with trichloracetic acid, and the amount of unprecipitated protein split products, which is a
M. L. Anson
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International Journal of Molecular Sciences, 2021 Pepsin refluxate is considered a risk factor for laryngopharyngeal carcinogenesis. Non-acidic pepsin was previously linked to an inflammatory and tumorigenic effect on laryngopharyngeal cells in vitro.
P. Doukas +3 more
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