Evaluation of the binding affinity and antioxidant activity of phlorizin to pepsin and trypsin [PDF]
Food Science and Human Wellness, 2023 Phlorizin (PHL) is a natural compound with strong antioxidant properties mainly found in apples. In this paper, the interaction mechanism of PHL with pepsin and trypsin was comparatively evaluated by computer simulation, fluorescence spectra, circular ...
Jing Zhang +7 more
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Combined laryngopharyngeal reflux and obstructive sleep apnea (CLOSA) - Salivary pepsin test for laryngopharyngeal reflux in obstructive sleep apnea patients. [PDF]
Tzu Chi Med JObjectives: Reflux disease including gastroesophageal reflux and laryngopharyngeal reflux (LPR) is often found in obstructive sleep apnea (OSA) patients. Endoscopic examination is a gold standard diagnosis for reflux disease.
Shen SC +8 more
europepmc +2 more sources
Pepsin Digestion for Proteomic Studies of the Human Hair Shaft. [PDF]
Rapid Commun Mass SpectromYee DH +4 more
europepmc +3 more sources
Analyzing pepsin degradation assay conditions used for allergenicity assessments to ensure that pepsin susceptible and pepsin resistant dietary proteins are distinguishable. [PDF]
PLoS ONE, 2017 The susceptibility of a dietary protein to proteolytic degradation by digestive enzymes, such as gastric pepsin, provides information on the likelihood of systemic exposure to a structurally intact and biologically active macromolecule, thus informing on
Rong Wang +8 more
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Effects of pepsin and pepstatin on reflux tonsil hypertrophy in vitro. [PDF]
PLoS ONE, 2018 There is evidence that pepsin can aggravate tonsil hypertrophy. Pepstatin is a potent inhibitor of pepsin activity and could protect patients against reflux tonsil hypertrophy by inhibiting pepsin.
Jin Hyun Kim +4 more
doaj +1 more source
PLoS ONE, 2020 Pepsin plays an important role in laryngopharyngeal reflux (LPR), a risk factor for the development of hypopharyngeal squamous cell carcinomas (HPSCC). However, the role of pepsin in HPSCC is not clear.
Kai Niu +8 more
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The In Vitro Effect of Acidic-Pepsin on Nuclear Factor KappaB Activation and Its Related Oncogenic Effect on Normal Human Hypopharyngeal Cells. [PDF]
PLoS ONE, 2016 Extra-esophageal carcinogenesis has been widely discussed in relation to the chronic effects of laryngopharyngeal reflux and most prominently with pepsin historically central to this discussion.
Clarence T Sasaki +2 more
doaj +1 more source
Sensors, 2020 Salivary pepsin is a promising marker for the non-invasive diagnosis of laryngopharyngeal reflux (LPR). For reliable results regarding pepsin in saliva, it is critical to standardize the collection, storage, and pre-processing methods.
Young Ju Lee +5 more
doaj +1 more source
Variability and accuracy of multiple saliva pepsin measurements in laryngopharyngeal reflux patients
Journal of Otolaryngology - Head and Neck Surgery, 2023 Objective To study the variability and diagnostic value of multiple salivary pepsin measurements in the detection of laryngopharyngeal reflux (LPR).
Jerome R. Lechien, Francois Bobin
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Extra-Esophageal Pepsin from Stomach Refluxate Promoted Tonsil Hypertrophy. [PDF]
PLoS ONE, 2016 Gastroesophageal reflux is associated with numerous pathologic conditions of the upper aerodigestive tract. Gastric pepsin within reflux contributes to immunologic reactions in the tonsil.
Jin Hyun Kim +7 more
doaj +1 more source