Laryngopharyngeal reflux (LPR) can contribute to chronic rhinosinusitis (CRS). Pepsin is believed to be one of the causes of CRS. Pepsin can be a promising biomarker because it is only produced by gastric parietal cells, so it can explain the correlation of CRS with LPR.
Aditya Wira Buana +2 more
openaire +1 more source
Salivary pepsin is a promising marker for the non-invasive diagnosis of laryngopharyngeal reflux (LPR). For reliable results regarding pepsin in saliva, it is critical to standardize the collection, storage, and pre-processing methods.
Young Ju Lee +5 more
doaj +1 more source
Variability and accuracy of multiple saliva pepsin measurements in laryngopharyngeal reflux patients
Objective To study the variability and diagnostic value of multiple salivary pepsin measurements in the detection of laryngopharyngeal reflux (LPR).
Jerome R. Lechien, Francois Bobin
doaj +1 more source
Extra-Esophageal Pepsin from Stomach Refluxate Promoted Tonsil Hypertrophy. [PDF]
Gastroesophageal reflux is associated with numerous pathologic conditions of the upper aerodigestive tract. Gastric pepsin within reflux contributes to immunologic reactions in the tonsil.
Jin Hyun Kim +7 more
doaj +1 more source
Kinetics of pepsin-induced hydrolysis and the coagulation of milk proteins
: Hydrolysis-induced coagulation of casein micelles by pepsin occurs during the digestion of milk. In this study, the effect of pH (6.7–5.3) and pepsin concentration (0.110–2.75 U/mL) on the hydrolysis of κ-casein and the coagulation of the casein ...
Mengxiao Yang +5 more
doaj +1 more source
The effect of dietary intake, physical activity and posture on pepsin concentrations detected in the saliva of free-living, healthy individuals [PDF]
Introduction: Diet and lifestyle are believed to be major causes of gastric reflux. The occurrence of reflux is associated with a number of respiratory, oesophageal and airways conditions.
Brownlee, Iain +8 more
core +2 more sources
Extraction and characterization of pepsin enzyme from the skipjack vicera (Katsuwonus pelamis) [PDF]
Pepsin is one of the digestive enzymes often used in various fields, especially for industry. Pepsin can be extracted from fish viceras. The aim of this research is to extract pepsin from the stomach of skipjack tuna, purify it, and to characterize ...
Muttaqin Roisul Adi Brilianto +6 more
doaj +1 more source
The use of phenyl-Sepharose for the affinity purification of proteinases [PDF]
Phenyl-Sepharose is most often used as an adsorbent for hydrophobic interaction chromatography (HIC). We report on its effective use for the affinity purification of some extracellular thermostable proteinases from bacterial sources.
Daniel, Roy M. +3 more
core +2 more sources
Binding interaction between (−)-epigallocatechin-3-gallate (EGCG) of green tea and pepsin [PDF]
Analysis of the binding interaction of (−)-epigallocatechin-3-gallate (EGCG) and pepsin is important for understanding the inhibition of digestive enzymes by tea polyphenols.
Feng, Y. +4 more
core +1 more source
High Ionic Strength Enhances the Anti-Pepsin Activity of Titanium Dioxide Nanoparticles
Gastro-esophageal reflux disease (GERD) is a state that evolves when there is a return of acid and pepsin enzyme into the esophagus. Inhibition of pepsin enzyme is one of the strategies used successfully for the treatment of GERD.
Hussein Kadhem Al-Hakeim +1 more
doaj +1 more source

