Results 21 to 30 of about 46,447 (263)

Immunoserologic Pepsin Detection in The Saliva as a Non-Invasive Rapid Diagnostic Test for Laryngopharyngeal Reflux

open access: yesBalkan Medical Journal, 2015
Background: The most common tool for the diagnosis of laryngopharyngeal reflux (LPR) is still 24-hours esophageal pH monitoring; there is lack of non-invasive, less expensive and accurate diagnostic tools for this frequent disease.
Emre Ocak, Gözde Kubat, İrfan Yorulmaz
doaj   +1 more source

Laryngopharyngeal Reflux: Symptoms, Signs, and Presence of Pepsin in Saliva - A Reliable Diagnostic Triad

open access: yesInternational Archives of Otorhinolaryngology, 2021
Introduction Twenty-four-hour multichannel intraluminal impedance with double probe pH monitoring (MII-pH), though considered the most sensitive tool for the diagnosis of gastroesophageal reflux disease (GERD), is invasive, time consuming, not widely ...
Shilpa Divakaran   +4 more
doaj   +1 more source

Label-Free Detection of Salivary Pepsin Using Gold Nanoparticle/Polypyrrole Nanocoral Modified Screen-Printed Electrode

open access: yesSensors, 2018
Detection of salivary pepsin has been given attention as a new diagnostic tool for laryngopharyngeal reflux (LPR) disease, because saliva collection is non-invasive and relatively comfortable.
Doyeon Lee   +3 more
doaj   +1 more source

Association between oropharyngeal ph-monitoring, pepsin saliva concentration and degree of apnea–hypopnea index of obstructive sleep apnea

open access: yesJournal of Otolaryngology - Head and Neck Surgery, 2023
Objective To investigate the association between obstructive sleep apnea (OSA) and laryngopharyngeal reflux (LPR) through oropharyngeal pH-monitoring and pepsin saliva measurements. Design Prospective uncontrolled study.
Francois Bobin, Jérôme R. Lechien
doaj   +1 more source

Diagnostic utility of salivary pepsin in laryngopharyngeal reflux: a systematic review and meta-analysis

open access: yesBrazilian Journal of Otorhinolaryngology, 2023
Objectives: Salivary pepsin has emerged as a biomarker for Laryngopharyngeal Reflux (LPR), which, however, has been questioned for its efficacy due to a lack of supporting medical data.
Wuyang Jing, Wenlong Luo, Lan Lou
doaj   +1 more source

Interactions and effects of food additive dye Allura red on pepsin structure and protease activity; experimental and computational supports

open access: yesResearch in Pharmaceutical Sciences, 2021
Background and purpose: Today, color additives such as Allura red (AR) are widely used in different kinds of food products. Pepsin is a globular protein that is secreted as a digestive protease from the main cells in the stomach. Because of the important
Fatemeh Balaei   +4 more
doaj   +1 more source

Salivary Pepsin as an Intrinsic Marker for Diagnosis of Sub- Types of GERD [PDF]

open access: yesAin Shams Medical Journal
Background: A stomach-based protease called pepsin has been linked to the etiology of GERD and may function as aprospective biomarker for disease evaluation.Aim: Our study's objective is to evaluate salivary pepsin's diagnostic accuracy as an intrinsic ...
sarah el nakeep   +4 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Diagnostic Value of Fasting and Bedtime Saliva Pepsin Measurements in Laryngopharyngeal Reflux

open access: yesBiomedicines
Background: The pepsin test is an emerging non-invasive diagnostic approach for laryngopharyngeal reflux (LPR). The aim of this study was to investigate the diagnostic value of multiple salivary pepsin tests for detecting LPR.
Jerome R. Lechien, Francois Bobin
doaj   +1 more source

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