Results 91 to 100 of about 92,278 (308)

The influence of in vitro gastrointestinal digestion on the chemical composition and antioxidant and enzyme inhibitory capacities of carob liqueurs obtained with different elaboration techniques [PDF]

, 2019
Carob liqueur is a traditional Mediterranean alcoholic beverage obtained via a wide range of production techniques contributing to the different organoleptic attributes of the final product.
Coelho, Natacha, Gonçalves, Sandra, Pérez-Santín, Efrén, Rodríguez Solana, Raquel, Romano, Anabela, Santos-Rufo, Antonio   +5 more
core   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

The reflux symptom score has good screening value for laryngopharyngeal reflux

BMC Gastroenterology
Objective To investigate the consistency between the reflux symptom score (RSS) and the multitemporal salivary pepsin test in screening for laryngopharyngeal reflux (LPR) and the screening value of the RSS for LPR by simultaneously administering daytime ...
Wenbin Guo, Jinhong Zhang, Huijun Yue, Kexing Lyu, Siyu Chen, Bixue Huang, Yiming Wang, Wenbin Lei   +7 more
doaj   +1 more source

Integrated Single‐Cell and Spatial Transcriptomics Reveal Cell‐Type‐Specific Immune Regulatory Networks in Maize Responding to Southern Corn Rust

Advanced Science, EarlyView.
By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang, Xinyan Sun, Yingchao Sun, Zeqiang Cheng, Zixiang Cheng, Shengbo Han, Ying Feng, Wenbo Yang, Huimin Li, Meichen Zhu, Xiaoling Wu, Jinghua Zhang, Jihua Tang, Honglian Li, Yanyong Cao, Canxing Duan, Yan Shi   +16 more
wiley   +1 more source

Aplikasi Enzim Pepsin Lambung Tuna terhadap Karakteristik Protein Daging Sapi

Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan
Pepsin dari lambung ikan tuna merupakan salah satu bentuk pemanfaatan hasil samping berupa enzim proteolitik yang dapat digunakan dalam bidang pangan. Enzim pepsin dapat diaplikasikan pada daging.
Tati Nurhayati, Roni Nugraha, Riki Kurniawan   +2 more
doaj   +1 more source

Human complement factor H [PDF]

, 1986
We isolated cDNA clones coding for the functionally important tryptic N-terminal38- kDa fragment of human complement control protein factor H using polyclonal and monoclonal antibodies to screen a human liver cDNA library cloned in a bacterial expression
Dierich, Manfred P., Schulz, T. F., Schwaeble, W., Stanley, K. K., Weiss, Elisabeth H.   +4 more
core   +1 more source

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

Advanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu, Yuxiang Ren, Tongyue Wang, Hongyong Li, Yue Yao, Lei Liu, Ke Sun, Peilong Lu   +7 more
wiley   +1 more source

The diagnostic value of pepsin detection in saliva for gastro-esophageal reflux disease: a preliminary study from China

BMC Gastroenterology, 2017
Background None of current diagnostic methods has been proven to be a reliable tool for gastro-esophageal reflux disease (GERD). Pepsin in saliva has been proposed as a promising diagnostic biomarker for gastro-esophageal reflux.
Xing Du, Feng Wang, Zhiwei Hu, Jimin Wu, Zhonggao Wang, Chao Yan, Chao Zhang, Juan Tang   +7 more
doaj   +1 more source

Live Imaging of Type I Collagen Assembly Dynamics in Osteoblasts Stably Expressing GFP and mCherry-Tagged Collagen Constructs [PDF]

, 2018
Type I collagen is the most abundant extracellular matrix protein in bone and other connective tissues and plays key roles in normal and pathological bone formation as well as in connective tissue disorders and fibrosis.
Bonewald, Lynda F., Dallas, Sarah L., Dusevich, Vladimir, Grillo, Michael A., Kamel-El Sayed, Suzan A., Lu, Yongbo, Phillips, Charlotte L., Tiede-Lewis, LeAnn M., Veno, Patricia A., Wang, Kun   +9 more
core   +2 more sources

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source