Results 61 to 70 of about 92,278 (308)

Antibacterial activity of a pepsin‐derived bovine hemoglobin fragment [PDF]

FEBS Letters, 2001
Peptic digestion of bovine hemoglobin yields a fragment with antibacterial activity. This peptide was purified to homogeneity by a two‐step procedure including anion exchange chromatography and preparative reversed‐phase HPLC. Mass determination and fragmentation indicated that this peptide corresponded to the 1–23 fragment of the α chain of hemoglobin.
Froidevaux, R., Krier, F., Nedjar-Arroume, N., Vercaigne-Marko, D., Kosciarz, E., Ruckebusch, C., Dhulster, P., Guillochon, D.   +7 more
openaire   +2 more sources

A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair

Advanced Healthcare Materials, EarlyView.
An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret, Ryan M. Friedman, Gautham Nair, Stephanie L. Fung, Dana D. Ragbirsingh, John Germiller, Riccardo Gottardi   +6 more
wiley   +1 more source

Diagnostic value of the pepsin concentration in saliva and induced sputum for gastroesophageal reflux-induced chronic cough: a prospective clinical study

ERJ Open Research
Background Finding a simple, effective and rapid diagnostic method to improve the diagnosis of gastroesophageal reflux-induced chronic cough (GERC) is indicated.
Wenhua Gu, Wei Chen, Tongyangzi Zhang, Yiqing Zhu, Wanzhen Li, Wenbo Shi, Na Li, Shengyuan Wang, Xianghuai Xu, Li Yu   +9 more
doaj   +1 more source

Aneusomy of chromosomes 7 and 17 predicts the recurrence of transitional cell carcinoma of the urinary bladder [PDF]

, 2000
Objective To determine if changes in chromosome 7 and 17 copy number can be used to predict recurrence in patients with primary noninvasive (pTa) or superficially invasive (pT1) transitional cell carcinoma (TCC) of the urinary bladder.
A.D. Watters, Bartlett, Bartlett, Cordon-cardo, Corless, Foresman, J.J. Going, J.M.S. Bartlett, K.M. Grigor, Kallioniemi, Knowles, McCredie, Murphy, Ozen, Povey, Pycha, Qureshi, S.A. Ballantyne, Sandberg, Saran, Sauter, Sauter, Sauter, Tolley, Underwood, Waldman, Yokogi   +26 more
core   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

Evaluation of the binding affinity and antioxidant activity of phlorizin to pepsin and trypsin

Food Science and Human Wellness
Phlorizin (PHL) is a natural compound with strong antioxidant properties mainly found in apples. In this paper, the interaction mechanism of PHL with pepsin and trypsin was comparatively evaluated by computer simulation, fluorescence spectra, circular ...
Jing Zhang, Di Wu, Lan Tang, Xia Hu, Zhen Zeng, Wen Wu, Fang Geng, Hui Li   +7 more
doaj   +1 more source

Cytotoxicity and Induction of Inflammation by Pepsin in Acid in Bronchial Epithelial Cells

International Journal of Inflammation, 2011
Introduction. Gastroesophageal reflux has been associated with chronic inflammatory diseases and may be a cause of airway remodelling. Aspiration of gastric fluids may cause damage to airway epithelial cells, not only because acidity is toxic to ...
Erik Bathoorn, Paul Daly, Birgit Gaiser, Karl Sternad, Craig Poland, William MacNee, Ellen M. Drost   +6 more
doaj   +1 more source

Identification and characterization of immunomodulatory peptides from pepsin–soy protein hydrolysates

Bioresources and Bioprocessing, 2022
To obtain immunomodulatory peptides from isolated soy protein (ISP), pepsin was selected to prepare hydrolysates and 4-h treatment (Pepsin-ISPH4h) showed the highest yield and immunomodulatory activities.
Lu-Sheng Hsieh, Ming-Shing Lu, Wen-Dee Chiang   +2 more
doaj   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Application of pepsin enzyme from yellowfin tuna gastrics on the physical and histological characteristics of beef [PDF]

BIO Web of Conferences
The increase in tuna production in Indonesia has introduced waste-management challenges. Utilizing pepsin from tuna stomachs for beef tenderization is a potential solution for the food industry.
Kurniawan Riki, Izzati Syifa Azmi Nurul, Nurhayati Tati, Jacoeb Agoes Mardiono   +3 more
doaj   +1 more source