Results 101 to 110 of about 166,295 (311)

Impact of long-term feeding a high level of Spirulina combined with enzymes on growth performance, carcass traits and meat quality in broiler chickens

Frontiers in Veterinary Science
This study evaluates the effect of prolonged feeding with a high inclusion level of Spirulina, combined with peptidases, on broiler chicken’s growth performance, digesta viscosity, carcass attributes and meat quality.
Maria P. Spínola, Maria P. Spínola, Mónica M. Costa, Mónica M. Costa, Beatriz Tavares, José M. Pestana, José M. Pestana, João C. Tavares, Cátia F. Martins, Cristina M. Alfaia, Cristina M. Alfaia, Verena Maciel, Verena Maciel, Daniela F. P. Carvalho, Miguel P. Mourato, Madalena M. Lordelo, José A. M. Prates, José A. M. Prates   +17 more
doaj   +1 more source

The Enhancing Effects of Peptidase Inhibitors on the Antinociceptive Action of [Met5]Enkephalin-Arg6-Phe7 in Rats

Journal of Pharmacological Sciences, 2007
Previous in vitro studies have shown that the degradation of [Met5]enkephalin-Arg6-Phe7 during incubation with cerebral membrane preparations is largely prevented by a mixture of three peptidase inhibitors: amastatin, captopril, and phosphoramidon.
Shigeru Takahashi, Xing Lu Jin, Kenya Kosaka, Masanobu Yoshikawa, Hiroyuki Kobayashi, Tetsuo Oka   +5 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Matrix processing peptidase of mitochondria [PDF]

, 1990
The mitochondrial processing peptidase (MPP) and the processing enhancing protein (PEP) cooperate in the proteolytic cleavage of matrix targeting sequences from nuclear-encoded mitochondrial precursor proteins.
Schneider, Helmut, Wachter, Elmar, Neupert, Walter, Arretz, Michael   +3 more
core  

The peptidase activity of human serum butyrylcholinesterase: studies using monoclonal antibodies and characterization of the peptidase

, 1993
Purified human serum butyrylcholinesterase, which exhibits cholinesterase, aryl acylamidase, and peptidase activities, was cross-reacted with two different monoclonal antibodies raised against human serum butyrylcholinesterase.
Rao, Rammohan V., Aiylam S. Balasubramanian, Balasubramanian, Aiylam S., Rammohan V. Rao   +3 more
core   +1 more source

Discrimination based on Gly and Arg/Ser at position 673 between dipeptidyl-peptidase (DPP) 7 and DPP11, widely distributed DPPs in pathogenic and environmental gram-negative bacteria [PDF]

, 2012
Porphyromonas gingivalis, an asaccharolytic gram-negative rod-shaped bacterium, expresses the novel Asp/Glu-specific dipeptidyl-peptidase (DPP) 11 (Ohara-Nemoto, Y. et al. (2011) J. Biol. Chem. 286, 38115–38127), which has been categorized as a member of
Rouf, Shakh M.A., Ohara-Nemoto, Yuko, Fujiwara, Taku, Hoshino, Tomonori, Ono, Toshio, Nemoto, Takayuki K.   +5 more
core   +1 more source

Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia

Journal of Neuroinflammation, 2012
Background Cerebral inflammation is a hallmark of neuronal degeneration. Dipeptidyl peptidase IV, aminopeptidase N as well as the dipeptidyl peptidases II, 8 and 9 and cytosolic alanyl-aminopeptidase are involved in the regulation of autoimmunity and ...
Röhnert Peter, Schmidt Werner, Emmerlich Patrick, Goihl Alexander, Wrenger Sabine, Bank Ute, Nordhoff Karsten, Täger Michael, Ansorge Siegfried, Reinhold Dirk, Striggow Frank   +10 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Peptidase activity in bovine growth hormone preparations

, 1967
Peptidase activity was detected in bovine growth hormone preparations supplied by the Endocrinology Study Section, National Institutes of Health. Two distinct protein peaks were obtained upon gel nitration of bovine growth hormone; peptidase activity was
Padayatty, Joseph D., Kley, Harold Van
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source