Results 241 to 250 of about 31,169 (289)
Some of the next articles are maybe not open access.
Peptidases in the Asthmatic Airways
2002Studies on the role of peptidases in the pathogenesis of asthma have not been able to convincingly demonstrate a dysfunction of these enzymes in the airways of stable asthmatics. Although asthmatic airways are more responsive to tachykinin-induced bronchoconstriction and nasal congestion (Joos et al 1987, Joos et al 1994), no apparent reduction in NEP ...
van der Velden, Vincent +5 more
openaire +3 more sources
INCREASE OF ENDO-PEPTIDASES AND EXO-PEPTIDASES IN THYROID-TUMORS
Oncology Reports, 1994Production of proteolytic enzymes is important for the invasive properties of malignant tumours. In this series of 43 cases of various non-neoplastic and neoplastic thyroid lesions, the activity of dipeptidyl peptidase I and dipeptidyl peptidase IV was increased in papillary carcinomas. In addition, cathepsin B and cathepsin L were markedly elevated in
L, Akslen +3 more
openaire +2 more sources
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1997
Proline is unique among the 20 amino acids due to its cyclic structure. This specific conformation imposes many restrictions on the structural aspects of peptides and proteins and confers particular biological properties upon a wide range of physiologically important biomolecules.
D F, Cunningham, B, O'Connor
openaire +2 more sources
Proline is unique among the 20 amino acids due to its cyclic structure. This specific conformation imposes many restrictions on the structural aspects of peptides and proteins and confers particular biological properties upon a wide range of physiologically important biomolecules.
D F, Cunningham, B, O'Connor
openaire +2 more sources
Methods in enzymology, 1994
This chapter highlights acylaminoacyl-peptidase enzyme, which catalyzes the removal of a blocked amino acid from a blocked peptide. The products of the reaction are an acyl amino acid and a peptide with a free N terminus shortened by one amino acid. The enzyme acts on a variety of substrates, including peptides with different N-terminal acyl groups ...
JONES WM, SCALONI A, MANNING JM
openaire +2 more sources
This chapter highlights acylaminoacyl-peptidase enzyme, which catalyzes the removal of a blocked amino acid from a blocked peptide. The products of the reaction are an acyl amino acid and a peptide with a free N terminus shortened by one amino acid. The enzyme acts on a variety of substrates, including peptides with different N-terminal acyl groups ...
JONES WM, SCALONI A, MANNING JM
openaire +2 more sources
2019
Signal peptidases are the membrane bound enzymes that cleave off the amino-terminal signal peptide from secretory preproteins . There are two types of bacterial signal peptidases . Type I signal peptidase utilizes a serine/lysine catalytic dyad mechanism and is the major signal peptidase in most bacteria.
openaire +2 more sources
Signal peptidases are the membrane bound enzymes that cleave off the amino-terminal signal peptide from secretory preproteins . There are two types of bacterial signal peptidases . Type I signal peptidase utilizes a serine/lysine catalytic dyad mechanism and is the major signal peptidase in most bacteria.
openaire +2 more sources