Results 231 to 240 of about 3,672,746 (390)

Elastomeric peptide

open access: yes, 2018
It is here claimed an oligopeptide of sequence SJXXZGXP (SEQ ID no. 7), where S is a serine, J is a serine or it is absent, X is independently any desired amino acid, Z is selected from tyrosine, histidine, phenylalanine or tryptophan, G is a glycine and P is a proline, characterized by the fact that at least the residue Z is substituted with at least ...
P. Metrangolo   +4 more
openaire   +2 more sources

Bioorthogonal Engineering of Cellular Microenvironments Using Isonitrile Ligations

open access: yesAdvanced Functional Materials, EarlyView.
Highly selective chemistries are required for fabrication and post‐cross–linking modification of cell‐encapsulating hydrogels used in tissue engineering applications. Isonitrile ligation reactions represent a promising class of bioorthogonal chemistries for engineering hydrogel‐based cellular microenvironments. Isonitrile‐based hydrogels are stable and
Ping Zhou   +2 more
wiley   +1 more source

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

open access: yesAdvanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham   +9 more
wiley   +1 more source

Poloxamer-based thermosensitive injectable hydrogels containing a self-assembling peptide for <i>In situ</i> gelation. [PDF]

open access: yesComput Struct Biotechnol J
Sayedipour SS   +8 more
europepmc   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer   +10 more
wiley   +1 more source

The Oxidation of Electron-Rich Arenes Using a H2O2–Proline System

open access: yesACS Omega
Lloyd C. Chetty   +5 more
doaj   +1 more source

Mass Spectrometry Imaging Demonstrates the Regional Brain Distribution Patterns of Three First-Line Antiretroviral Drugs

open access: yesACS Omega, 2019
Sphamandla Ntshangase   +6 more
doaj   +1 more source

Accurate affinity models for SH2 domains from peptide binding assays and free-energy regression. [PDF]

open access: yesProtein Sci
Gagoski D   +7 more
europepmc   +1 more source

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