Results 231 to 240 of about 3,438,161 (393)

Enhancing the selectivity and conditional sensitivity of an antimicrobial peptide through cleavage simulations and homoarginine incorporation to combat drug-resistant bacteria. [PDF]

Sci Rep
Yao K, Liu J, Sun R, Wang Y, Jiang Y, Wang T, Chen X, Ma C, Chen T, Shaw C, Zhou M, Wang L.   +11 more
europepmc   +1 more source

Mass Spectrometry Imaging Demonstrates the Regional Brain Distribution Patterns of Three First-Line Antiretroviral Drugs

ACS Omega, 2019
Sphamandla Ntshangase, Sipho Mdanda, Sanil D. Singh, Tricia Naicker, Hendrik G. Kruger, Sooraj Baijnath, Thavendran Govender   +6 more
doaj   +1 more source

Peptide Antimicrobial Agents

Clinical Microbiology Reviews, 2006
H. Jenssen, P. Hamill, R. Hancock
semanticscholar   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Antimicrobial Peptides Design Using Deep Learning and Rational Modifications: Activity in Bacteria, Candida albicans, and Cancer Cells. [PDF]

Curr Microbiol
Mesa A, Orrego A, Branch-Bedoya JW, Mera-Banguero C, Orduz S.   +4 more
europepmc   +1 more source

Elastomeric peptide

, 2018
It is here claimed an oligopeptide of sequence SJXXZGXP (SEQ ID no. 7), where S is a serine, J is a serine or it is absent, X is independently any desired amino acid, Z is selected from tyrosine, histidine, phenylalanine or tryptophan, G is a glycine and P is a proline, characterized by the fact that at least the residue Z is substituted with at least ...
P. Metrangolo, F. Baldelli, A. Pizzi, M. Linder, M. Pezhman   +4 more
openaire   +2 more sources

Stable, Easy‐to‐Handle, Fully Autologous Electrospun Polymer‐Peptide Skin Equivalent for Severe Burn Injuries

Advanced Functional Materials, EarlyView.
A bioengineered skin equivalent composed of electrospun poly(ε‐caprolactone) (PCL) and the bioactive peptide Fmoc‐FRGD is developed for severe burn treatment. This scaffold promotes full‐thickness skin regeneration by supporting cellular adhesion and integration. In‐vitro and in‐vivo studies show enhanced mechanical stability, accelerated wound closure,
Dana Cohen‐Gerassi, Marina BenShoshan, Adi Liiani, Tomer Reuveni, Offir Loboda, Moti Harats, Josef Haik, Itzhak Binderman, Yosi Shacham‐Diamand, Amit Sitt, Ayelet Di Segni, Lihi Adler‐Abramovich   +11 more
wiley   +1 more source

Peptide-Drug Conjugates: A New Hope for Cancer. [PDF]

J Pept Sci
Armstrong A, Coburn F, Nsereko Y, Al Musaimi O.   +3 more
europepmc   +1 more source

THE CONJUGATED, NON-PROTEIN, AMINO ACIDS OF PLASMA. IV. A DIFFERENCE IN THE UTILIZATION OF THE PEPTIDES OF HYDROLYSATES OF FIBRIN AND CASEIN [PDF]

, 1947
Halvor N. Christensen, Eleanor L. Lynch, David G. Decker, John H. Powers   +3 more
openalex   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source