Results 261 to 270 of about 1,752,184 (298)
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The Quarterly Journal of Nuclear Medicine and Molecular Imaging, 2020
In recent years, the introduction of theranostic twins for specific diagnosis and treatment in patients with neuroendocrine tumors became a nuclear medicine success story. 64Cu/18F labeled prostate specific membrane antigen (PSMA) for molecular imaging with PET-CT and peptide radioligand therapy with 177Lu labeled PSMA inhibitors will favorably become ...
Siroos, Mirzaei, Rainer W, Lipp
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In recent years, the introduction of theranostic twins for specific diagnosis and treatment in patients with neuroendocrine tumors became a nuclear medicine success story. 64Cu/18F labeled prostate specific membrane antigen (PSMA) for molecular imaging with PET-CT and peptide radioligand therapy with 177Lu labeled PSMA inhibitors will favorably become ...
Siroos, Mirzaei, Rainer W, Lipp
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Journal of Peptide Science, 2005
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Petr, Niederhafner +2 more
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AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Petr, Niederhafner +2 more
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Peptide Vaccines and Peptide Libraries
Biological Chemistry, 2001Synthetic immunogens, containing built-in adjuvanticity, B cell, T helper cell and CTL epitopes or mimotopes, are ideal and invaluable tools to study the immune response with respect to antigen processing and presentation. This serves as a basis for the development of complete and minimal vaccines which do not need large carrier proteins, further ...
K H, Wiesmüller +2 more
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Peptide chemistry toolbox – Transforming natural peptides into peptide therapeutics
Bioorganic & Medicinal Chemistry, 2018The development of solid phase peptide synthesis has released tremendous opportunities for using synthetic peptides in medicinal applications. In the last decades, peptide therapeutics became an emerging market in pharmaceutical industry. The need for synthetic strategies in order to improve peptidic properties, such as longer half-life, higher ...
Miloš, Erak +3 more
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Journal of the American Chemical Society, 2002
Electrospraying a mixture of Ac-(GA)7K and Ac-A(GA)7K (Ac = acetyl, G = glycine, A = alanine, and K = lysine) peptides produces strong signals for unsolvated dimers and trimers. The conformations of these multimers have been examined with use of ion mobility measurements in conjunction with molecular dynamics simulations.
David T, Kaleta, Martin F, Jarrold
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Electrospraying a mixture of Ac-(GA)7K and Ac-A(GA)7K (Ac = acetyl, G = glycine, A = alanine, and K = lysine) peptides produces strong signals for unsolvated dimers and trimers. The conformations of these multimers have been examined with use of ion mobility measurements in conjunction with molecular dynamics simulations.
David T, Kaleta, Martin F, Jarrold
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1995
If we include beta-lactam antibiotics on the grounds that they have the same biosynthetic origin, peptides remain commercially the most important group of pharmaceuticals. However, our increasing knowledge of the genetic and enzymic background to biosynthesis, and of the regulation of metabolite production, will eventually bring a more unified approach
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If we include beta-lactam antibiotics on the grounds that they have the same biosynthetic origin, peptides remain commercially the most important group of pharmaceuticals. However, our increasing knowledge of the genetic and enzymic background to biosynthesis, and of the regulation of metabolite production, will eventually bring a more unified approach
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The FASEB Journal, 1995
Although most short, linear peptide fragments of proteins are unstructured in aqueous solution, a number of immunogenic and antigenic peptides have been shown to have conformational preferences for structured forms. By using mainly NMR and CD spectroscopy, it has been possible to detect and quantify quite small populations of β ...
H J, Dyson, P E, Wright
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Although most short, linear peptide fragments of proteins are unstructured in aqueous solution, a number of immunogenic and antigenic peptides have been shown to have conformational preferences for structured forms. By using mainly NMR and CD spectroscopy, it has been possible to detect and quantify quite small populations of β ...
H J, Dyson, P E, Wright
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Surgical Infections, 2018
Bacterial resistance to available antibiotics has resulted in enhanced efforts at antibiotic stewardship but also has led to investigation into alternative methods for managing surgical infections. Antimicrobial peptides (AMPs) are naturally occurring compounds produced by all prokaryotic and eukaryotic cells that have potential as an alternative to ...
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Bacterial resistance to available antibiotics has resulted in enhanced efforts at antibiotic stewardship but also has led to investigation into alternative methods for managing surgical infections. Antimicrobial peptides (AMPs) are naturally occurring compounds produced by all prokaryotic and eukaryotic cells that have potential as an alternative to ...
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Baillière's Clinical Gastroenterology, 1996
There is a growing body of evidence supporting the hypothesis that members of the trefoil peptide family are involved actively in maintaining the integrity of the gastrointestinal mucosa and facilitating its repair. To date, three trefoil peptides are known in man: pS2, ITF and SP.
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There is a growing body of evidence supporting the hypothesis that members of the trefoil peptide family are involved actively in maintaining the integrity of the gastrointestinal mucosa and facilitating its repair. To date, three trefoil peptides are known in man: pS2, ITF and SP.
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Peptides: Locally Active Peptides (“Vasoactive Peptides”)
1982Angiotensin may be considered the prototype of the so-called vasoactive peptides inasmuch as its predominant effect is on vascular smooth muscle, which is constricted by both direct and indirect effects of the peptide. However, angiotensin may affect contractility of much extravascular smooth muscle with a predominantly, if not exclusively, stimulatory
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