Results 71 to 80 of about 3,707,949 (340)

Increased serum levels of procollagen type III peptide in severely injured patients [PDF]

open access: yes, 1993
Objectives: To determine the serum concentrations of procollagen type in peptide in severely injured patients with different outcomes and to evaluate the relationship between serum procollagen type III peptide concentrations, sources of increased ...
Duswald, Karl-Heimo   +6 more
core  

Quantification of gliadin levels to the picogram level by flow cytometry [PDF]

open access: yes, 2005
Celiac disease is a widely prevalent enteropathy caused by intolerance to gliadin, one of the gluten proteins. We developed two methods for the analysis of gliadin levels. Both methods use flow cytometry and rat antibodies against a 16-residue peptide of
CAPPARELLI R   +3 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Apex Peptide Elution Chain Selection: A New Strategy for Selecting Precursors in 2D-LC-MALDI-TOF/TOF Experiments on Complex Biological Samples [PDF]

open access: yes, 2010
LC-MALDI provides an often overlooked opportunity to exploit the separation between LC-MS and MS/MS stages of a 2D-LC-MS-based proteomics experiment, that is, by making a smarter selection for precursor fragmentation. Apex Peptide Elution Chain Selection
Breitling, Rainer,   +5 more
core   +3 more sources

Crystal structure of butyl 2-(3,5-dimethyl-1,1-dioxido-2H-1,2,6-thiadiazin-4-yl)benzoate, C16H20N2O4S

open access: yesZeitschrift für Kristallographie - New Crystal Structures, 2016
C16H20N2O4S, monoclinic, P21/n (no. 14), a = 9.229(2) Å, b = 16.995(4) Å, c = 11.084(3) Å, β = 99.985(11)°, V = 1712.3(8) Å3, Z = 4, Rgt(F) = 0.0393, wRref(F2) = 0.1081, T = 173.
Bhatt Nilay   +5 more
doaj   +1 more source

Naturally Occurring Oxazole-Containing Peptides

open access: yesMarine Drugs, 2020
Oxazole-containing peptides are mostly of marine origin and they form an intriguing family with a broad range of biological activities. Here we classify these peptides on the basis of their chemical structure and discuss a number of representatives of ...
Jessica T. Mhlongo   +3 more
doaj   +1 more source

An antitumor peptide RS17‐targeted CD47, design, synthesis, and antitumor activity

open access: yesCancer Medicine, 2021
Background CD47 is a widely expressed transmembrane protein located on the surface of somatic cells. It mediates a variety of cellular processes including apoptosis, proliferation, adhesion, and migration.
Xinmin Wang   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Thermodynamics and Kinetics of Folding of a Small Peptide

open access: yes, 2001
We study the thermodynamics and kinetics of folding for a small peptide. Our data rely on Monte Carlo simulations where the interactions among all atoms are taken into account.
Hansmann, Ulrich H. E., Onuchic, Jose N.
core   +2 more sources

Microprotein-encoding RNA regulation in cells treated with pro-inflammatory and pro-fibrotic stimuli

open access: yesBMC Genomics
Background Recent analysis of the human proteome via proteogenomics and ribosome profiling of the transcriptome revealed the existence of thousands of previously unannotated microprotein-coding small open reading frames (smORFs).
Victor J. Pai   +13 more
doaj   +1 more source

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