Results 161 to 170 of about 589,641 (293)

On-chip engineering of EDC-crosslinked antimicrobial peptide hydrogels for enhanced eradication of MRSA infections. [PDF]

RSC Adv
Huang D, Lin F, Yang N, Qian X, Li J, Su M, Hu R, Tian Y, Han F, Guo G.   +9 more
europepmc   +1 more source

Enzyme-triggered self-assembly of peptide hydrogels via reversed hydrolysis

, 2008
Enzyme-triggered self-assembly of peptide hydrogels via reversed ...
Richard Williams (13100049), RV Ulijn (14539211)   +1 more
core  

Matrix Stiffness Orchestrates Mesenchymal Stem Cell Lineage Commitment Toward Osteogenesis and Adipogenesis Through the PIEZO1/SP1/STC2 Axis

Advanced Science, EarlyView.
Matrix stiffness directs mesenchymal stem cell lineage commitment through PIEZO1‐dependent activation of the SP1/STC2 pathway. Stiff matrices favor osteogenesis and suppress adipogenesis, whereas the loss of PIEZO1 function impairs early bone formation. STC2 retains lineage‐regulatory activity even when PIEZO1 is inactive.
Shuo Zhang, Siteng Li, Wenzhong Chen, Qingcheng Song, Haiyue Zhao, Peng Wang, Yiran Zhang, Wenquan Liang, Shaowei Zheng, Juan Wang, Wei Chen, Yanbin Zhu, Yingze Zhang   +12 more
wiley   +1 more source

Injectable dual-affinity self-assembling peptide hydrogels for local controlled delivery of therapeutic antibodies. [PDF]

Asian J Pharm Sci
Cui W, Zhang L, Yang C, He B, Zhang H, Wang X, Zhang Z, Zhang Q, Dai W.   +8 more
europepmc   +1 more source

Peptide-functionalized hydrogels for three-dimensional cell culture

, 2016
University of Minnesota Ph.D. dissertation. June 2016. Major: Biomedical Engineering. Advisor: Efrosini Kokkoli. 1 computer file (PDF); ix, 100 pages.Biomimetic scaffolds have played a major role in the advancements in tissue engineering. In addition to
Scott, Carolyn
core  

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

Artificial intelligence-assisted design of self-assembling peptide hydrogels for neural regeneration: Principles and opportunities. [PDF]

Bioact Mater
Zhou Y, Jiang X, Zhang X, Yao X, Gao Z, Chen X, Gong L, Jie J, Yang Y, Yang P.   +9 more
europepmc   +1 more source

Sequential Patterning of Photoresponsive Hydrogels Directs Crypt Fission and Reveals the Role of Epithelial Curvature on Fission Symmetry

Advanced Science, EarlyView.
Deterministic crypt fission is achieved in intestinal organoids using photopatternable hydrogels with spatiotemporal control. Daughter‐crypt symmetry is shown to depend on parent‐crypt geometry and epithelial curvature, while myosin‐dependent mechanosensing links tissue shape to regenerative outcomes.
Delaney L. McNally, Kaustav Bera, Nolan R. Petrich, Alex Khang, Marilyne Coulombe, David Castillo‐Azofeifa, Ophir D. Klein, Peter J. Dempsey, Kristi S. Anseth   +8 more
wiley   +1 more source

Mechanically Enhanced Ultrashort Peptide Hydrogels for pH-Triggered Release. [PDF]

ACS Polym Au
Scognamiglio PL, Diaferia C, Pizzella M, Accardo A, Morelli G, Tesauro D.   +5 more
europepmc   +1 more source

Restoration of m6A‐Modified circPSMB1 Suppresses Chordoma Progression and Enables Local Nanotherapeutic Intervention

Advanced Science, EarlyView.
An m6A‐modified circRNA, circPSMB1, is identified as a tumor suppressor in chordoma. METTL3‐dependent m6A promotes circPSMB1 interaction with HNRNPA2B1, limiting c‐MYC expression and malignant progression. An injectable HMnO2‐based nanohydrogel enables local circPSMB1 delivery and tumor microenvironment‐responsive therapy, offering a promising strategy
Yingchuang Tang, Liang Qiu, Xingbang Ruan, Yihan Shi, Ye Wang, Hanwen Li, Kai Zhang, Kangwu Chen   +7 more
wiley   +1 more source