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Antimicrobial
Biofilms are widely involved in human lives, such as in medical infection, environmental remediation, and industrial processes. However, the control of the biofilm has still been a challenge because of its strong drug resistance. Here, we designed and synthesized an amphipathic antimicrobial peptide (Ac-DKDHDHDQDKDLDVDFDFDADK-NH2 (KKd-11)) that was ...
Zhen Guo +5 more
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Self-healing cyclic peptide hydrogels
Journal of Materials Chemistry B, 2023The structural design principles of cyclic peptides-based hydrogels are introduced. The resulting soft materials exhibited self-healing capabilities.
Alfonso Bayón-Fernández +4 more
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Peptide hydrogels: mimicking the extracellular matrix
Bioinspired, Biomimetic and Nanobiomaterials, 2012The extracellular matrix (ECM) is a complex and dynamic three-dimensional (3D) environment consisting largely of a variety of collagenous and non-collagenous fibres, non-fibrous proteins and proteoglycans. Other components often overlooked include various growth factors and other signalling molecules which can diffuse through and bind to various ...
Gough, JE; id_orcid 0000-0002-1270-0616 +2 more
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Mechanics of single peptide hydrogelator fibrils
Nanoscale, 2015The rigidity of peptide fibers is essential for their chemical and biological functions, despite that it remains largely unexplored.
Ying, Li +4 more
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Branched peptides for enzymatic supramolecular hydrogelation
Chemical Communications, 2018The use of protease ( e.g. , enterokinase) to cut branched peptides generates supramolecular hydrogels, opening a new way to explore soft materials for biomedicine.
Hongjian He +4 more
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Hybrid Peptide–Agarose Hydrogels for 3D Immunoassays
2022Recent advances in biosensing analytical platforms have brought relevant outcomes for novel diagnostic and therapy-oriented applications. In this context, 3D droplet microarrays, where hydrogels are used as matrices to stably entrap biomolecules onto analytical surfaces, potentially provide relevant advantages over conventional 2D assays, such as ...
Angelo Musicò +6 more
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Short peptide based hydrogels: incorporation of graphene into the hydrogel
Soft Matter, 2011Stable supramolecular hydrogels were obtained from Fmoc (N-fluorenyl-9-methoxycarbonyl) protected synthetic dipeptides, Fmoc-Xaa-Asp-OH (Xaa = Tyr, Phe). These hydrogels were characterized by various methods including transmission electron microscopy (TEM), field-emission scanning electron microscopy (FE-SEM), atomic force microscopy (AFM ...
Bimalendu Adhikari, Arindam Banerjee
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Langmuir, 2014
We have investigated the effect of doping the self-assembling octapeptide FEFEFKFK (F, phenylalanine; E, glutamic acid; K, lysine) hydrogels with various amounts of thermoresponsive conjugate of FEFEFKFK and poly(N-isopropylacrylamide) (PNIPAAm) in order to create novel hydrogels.
Maslovskis, A +5 more
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We have investigated the effect of doping the self-assembling octapeptide FEFEFKFK (F, phenylalanine; E, glutamic acid; K, lysine) hydrogels with various amounts of thermoresponsive conjugate of FEFEFKFK and poly(N-isopropylacrylamide) (PNIPAAm) in order to create novel hydrogels.
Maslovskis, A +5 more
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Minimal Peptide Motif for Non-covalent Peptide–Heparin Hydrogels
Journal of the American Chemical Society, 2013Reduction of complexity of the extracellular matrix (ECM) to a non-covalent structure with minimal chemically defined components represents an attractive avenue for understanding the biology of the ECM. The resulting system could lead to the design of tailor-made biomaterials that incorporate varying functionalities.
Robert, Wieduwild +8 more
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