Results 201 to 210 of about 572,875 (296)

Molecular Mechanisms of Programmed Cell Death During Somatic Embryo Detachment from Callus in Indirect Somatic Embryogenesis. [PDF]

Int J Mol Sci
Huang H, Ma Z, Sun T, Wang F.
europepmc   +1 more source

Proteostasis in the regulation of pancreatic islet cell plasticity

Journal of Diabetes Investigation, EarlyView.
Adaptive proteostasis integrates protein synthesis, folding, trafficking, and degradation through ISR, UPR, ER stress responses, autophagy, and proteasomal degradation. In pancreatic islet cells, this coordinated network preserves protein quality, secretory function, proliferation, and survival, enabling adaptation to metabolic stress and aging while ...
Jun Shirakawa
wiley   +1 more source

Structure-Guided Extremophile Genome Mining Expands the PETase Landscape and Reveals PET-Hydrolysing True Lipase Lineages. [PDF]

Microb Biotechnol
Muñoz-Tafalla R, González-Romero JM, Vidal P, Fernandez-Lopez L, Robles-Martín A, Almendral D, Gonzalez-Alfonso JL, Plou FJ, Ferrer M, Guallar V, Bargiela R.   +10 more
europepmc   +1 more source

Structural organization of the rat acyl-peptide hydrolase gene

Nucleic Acids Research, 1989
L W, Lin, F J, Lee, J A, Smith
openaire   +3 more sources

The TaRNS4–TaPP2C10 module regulates wheat resistance to stripe rust through RNA degradation and MAPK cascades

Journal of Integrative Plant Biology, EarlyView.
In wheat, phosphorylation of the S‐like RNase TaRNS4 mediated by the kinase TaRLK5 promotes its degradation of Puccinia striiformis f. sp. tritici RNA in the apoplast, enhancing resistance to stripe rust. TaRNS4 can hijack phosphatase TaPP2C10 to relieve its dephosphorylation of TaMAPK6, thereby activating MAPK‐mediated immune responses. ABSTRACT RNase
Qiao Wang, Hongxu Zuo, Mantong Lu, Ying Li, Juan Li, Ming Qin, Peng Cheng, Qiang Li, Baotong Wang   +8 more
wiley   +1 more source

How AFM has contributed to the understanding of bacterial cell wall peptidoglycan structure

Journal of Microscopy, EarlyView.
Abstract The bacterial cell wall is an essential exoskeleton that plays a major role in conferring cell shape, serving as the primary stress‐bearing layer, resisting the several atmospheres turgor pressure created by the imbalance in molecular concentrations between the cell interior and the surrounding medium, while also playing a central role in host‐
Abimbola Feyisara Adedeji‐Olulana, Ankita Ray, Timothy Chester‐Parsons, Alexander Knight, Alexander I. Tartakovskii, Simon Foster, Jamie K. Hobbs   +6 more
wiley   +1 more source

Specificity and recognition of the ADP-ribosyl-ubiquitin modification in the DNA damage response. [PDF]

PLoS Biol
Chatrin C, Zhu K, Simmons MDR, Maginn L, Schützenhofer K, Lu Y, Đukić N, Wijngaarden S, Kloet MS, Kliza KW, Heden van Noort GJV, Filippov DV, Ahel D, Smith R, Ahel I.   +14 more
europepmc   +1 more source

Microbiome‐Dependent Modulation of Trichomonas vaginalis Cytotoxicity and Remodeling of the Parasite Secretome

Molecular Microbiology, EarlyView.
Our study shows that vaginal bacteria can either suppress or amplify the pathogenic behavior of the protozoan parasite Trichomonas vaginalis. A protective Lactobacillus‐dominated microbiome in eubiosis reduces parasite‐induced damage, whereas dysbiotic bacteria enhance cytotoxicity, followed by changes in the profile of the parasite's secreted proteins.
Bailey S. Dickson, Ann‐Katrein Bär, Augusto Simoes‐Barbosa   +2 more
wiley   +1 more source

Membrane-targeting antimicrobials trigger lysis in Bacillus subtilis by disturbing the MreB-dependent regulation of peptidoglycan hydrolases

Seistrup KH, Koh A, Strahl H.
europepmc   +1 more source

The crystal structure of human transport and Golgi organization 2 homolog (TANGO2) suggests a cysteine N-terminal nucleophile (Ntn) hydrolase. [PDF]

Acta Crystallogr D Struct Biol
Zhou D, Chen L, Rose J, Wang BC.
europepmc   +1 more source